Surfactant replacement therapy is the mainstay treatment for preterm infants with respiratory distress syndrome. In recent years, the growing interest in non-invasive ventilation has led to a variety of novel approaches of surfactant administration (intra-amniotic instillation, pharyngeal instillation, administration via laryngeal mask airway, administration via thin endotracheal catheter without IPPV, aerosolized/nebulized surfactant administration in spontaneously breathing infants). In our Centre last year a number of preterm infants with RDS were treated using MIST technique, in which surfactant is administered using a thin feeding tube inserted below the vocal cords. In the paper we describe our experience with the novel technique and report short term outcomes.

Darjan Kardum,
Neonatal Intensive Care Unit, Department of Paediatrics,
University Hospital Osijek, J. Huttlera 4, 31000 Osijek, Croatia

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