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Signa Vitae

A Journal In Intensive Care And Emergency Medicine

Category: Articles (Page 1 of 80)

Admission to NICU in air is more likely if nasal High Flow is used for stabilisation in preterm babies compared to face mask CPAP


Objective. To examine the success of stabilisation and the short term outcomes from the routine use of nasal high flow (nHF) on an unselected cohort of babies in the delivery room (DR).

Design. Retrospective single-centre study

Setting. Single-centre neonatal intensive care unit (NICU)

Patients. Infants born at < 32 weeks gestation

Interventions. Stabilisation and transfer to NICU of an unselected cohort of babies using nHF

Main outcome measures. Success of stabilisation defined by successful transfer on nHF and clinical measures of stability at admission to NICU, including oxygen requirement, admission temperature, surfactant requirement, short term outcomes and whether infants were sustained on nHF by 72 hours of age.

Results. There were 133 eligible babies. 54 were commenced on nHF in the DR (Group A), 47 were stabilised by face mask CPAP (continuous positive airway pressure) (Group B), 26 were intubated (Group C); 6 required only minimal respiratory support (Group D). Median maturity varied between the groups (Group A 27+5 weeks, Group B 30 weeks, Group C 26+2 weeks, Group D 31+5). 72% of Group A and 75% of Group B remained on nHF for 72 hours (P=0.82). Fewer babies received surfactant in Group A versus Group B (29% vs 35%; P=0.67), however groups were not matched for maturity differences and Group A were significantly less mature and of lower birthweight (both P<0.001). Group A were significantly more likely to be in air at admission than Group B (P=0.03).

Conclusion. Preterm babies can be successfully stabilised and sustained on nHF. The use of nHF for immediate stabilisation appears to be effective and, in this study, led to significantly more babies being in air on admission to the NICU compared to face mask CPAP stabilisation.

Key words: nasal High Flow cannula, delivery room, stabilisation, premature

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A case report of pulmonary vascular air embolism in elbw premature neonate


Pulmonary vascular air embolism is a rare and almost fatal complication of positive pressure ventilation  in premature neonates with respiratory distress syndrome

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 The human microbiome in health and disease

Humans consist only of our own somatic cells until birth, but over the first several years of life, our bodies, including the skin surface, mammary glands, placenta, seminal fluid, uterus, ovarian follicles, lung, saliva, oral mucosa, conjuctiva and gastrointestinal tracts are colonized by an enormous variety of bacteria, archaea, protists, fungi and viruses, which form a community collectively known as the human microbiota. The human microbiome refers specifically to the collective genomes of resident microorganisms.

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2nd South Eastern European Joint Meeting of Thoracic Anesthesiologists and Surgeons (Book of abstracts)

Slovenia, Ljubljana, 12-13 April, 2017


University Medical Centre Ljubljana

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Early VATS for Blunt Chest Trauma


The role of Video-Assisted Thoracoscopic Surgery (VATS) is still being defined in the management of thoracic trauma. We reported our isolated blunt chest trauma cases managed by VATS and reviewed the role of VATS in the management of this kind of thoracic trauma.

Keywords: blunt thoracic trauma, haemothorax, Video-Assisted Thoracoscopic Surgery.

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