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Signa Vitae

Journal of Anaesthesia, Intensive Care and Emergency Medicine

Quality of life in lung cancer patients due to treatment


Lung cancer is the second most common cancer in men and women. Survival has not significantly improved despite new therapeutic possibilities. Therefore, in patients with end-stage disease, the primary goal is to preserve the quality of life as long as possible.

The study included patients divided into four groups depending on the treatment: treated with chemotherapy, radiotherapy, a combination of chemotherapy and radiotherapy and patients treated with symptomatic therapy. Each group consists of 30 subjects. We measured quality of life using a questionnaire of the European Association for the Study and Treatment of Cancer in addition of no.13 for lung cancer (EORTC QLQ C30 + LC13), which is validated and translated in the native language and includes 43 questions.

Patients who are on symptomatic therapy have the worst quality of life, and all aspects of normal functioning are the most disturbed when compared to patients treated with other therapeutic modalities. Quality of life is best for patients who are treated with chemotherapy. Any modality of treatment, especially chemotherapy, is superior to the use of only symptomatic treatment.

Key words: lung cancer, quality of life, chemotherapy

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Nonintubated video-assisted thoracoscopic surgery (VATS)


Video –assisted thoracoscopic surgery (VATS) has become common and globally accepted surgical approach for a variety of thoracis diseases. Conventionally, it is performed under tracheal intubation with double lumen tube or bronchial blocker to achieve single lung ventilation. Nonintubated video-assisted thoracoscopic surgery (VATS) has been reported to be safe and feasible for patients with various thoracic diseases, including those who have respiratory dysfunction. VATS without tracheal intubation is safe in a series of VATS procedures, including management of pneumothorax, wedge resection of pulmonary tumors, excision of mediastinal tumors, lung volume reduction surgery, segmentectomy and lobectomy. Patiens undergoing nonintubated VATS are anesthetized using regional anesthesia in a spontaneously single lung breathing status after iatrogenic open pneumothorax. Therefore, we need to minimize the patients physical and psyichological discomfort by using sedation or intrathoracic vagal blockade on the surgical side, if analgesia and sedation are inadequate, conversion to intubated general anesthesia may be required. The early outcomes of nonintubated VATS include faster postoperative recovery and less complication rate comparing with its counterpart of intubated general anesthesia.

Key words: Nonintubated video-assisted thoracoscopic  surgery (VATS), regional anesthesia, lung cancer, analgesia and sedation

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The use of a smartphone application for fast lung cancer risk assessment


The early detection of NSCLC cases is still the key point of the surgical treatment of lung cancer, but 75% of the cases are still diagnosed in an advanced, inoperable stage. Screening with ldCT of the high risk population can improve the early diagnosis, but it might be aggravated by the complex task of risk group selection and recruitment. The modern communication path of the mobile devices are enabling us a complete new communication and selection method wich can effectively simplify the risk group identification and the suggestion of screening by the Screening Centers. The aim of our study was to determine the effectivity of a lung cancer risk assessment mobile application (LungScreen) in a localised setting.

Key words: lung cancer, screening, VATS lobectomy

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