We showed the case of a sixty-five-year-old woman who developed refractory septic shock as a result of endocarditis of the native mitral valve with maintained neat systolic function of the left ventricle and moderate mitral regurgitation. Streptococcus sanguinis was isolated from hemoculture. The patient did not have clearly known predisposing factors for the development of endocarditis, nor had elevated temperature. She died 32 hours after being admitted to the hospital.

Key words: endocarditis, native mitral valve, refractory septic shock

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