RT - Signa Vitae ID - 10.22514/SV101.062015.29 T1 - Toxicological screening - Experience from University Hospital Centre Zagreb Emergency Medical Service A1 - ANDRIJANA ŠČAVNIČAR A1 - PAULA GRANIĆ A1 - MILA LOVRIĆ A1 - DUNJA ROGIĆ K1 - gas chromatography K1 - mass spec-trometry K1 - toxicological screening YR - 2015 SP - 92 AB -

The aim of toxicological screening is to de-tect drugs of abuse and other drugs, or to demonstrate that they have not been taken. It is performed with a variety of tests capa-ble to detect certain substance or a group of substances. Urine is a sample of choice for toxicological screening because of less invasive sampling and the prolonged de-tection time of substances in urine. The Department of Laboratory Diagnostics at the University Hospital Centre Zagreb used to perform screening with thin-layer chromatography and confirm results with GC-MS analysis. Since September 2014, the Department has been using GC-MS for toxicological screening 24 hours a day. Compared to the previous period, the ex-perience acquired so far has shown that there are a significantly lower number of samples with unknown substances that cannot be confirmed with certainty.