RT  - Signa Vitae
ID  - 10.22514/SV101.062015.9
T1  - Indications for blood transfusions in critical illness
A1  - ROBERT BARONICA
A1  - DINKO TONKOVIĆ
A1  - BOJANA ĐUROVIĆ MRŽLJAK
A1  - LOREDANA ĐURIĆ
A1  - TIHOMIR KUŠIĆ
A1  - KAROLINA REŽEK
K1  - haemoglobin concentration
K1  - global oxygenation parameters
K1  - transfusion
K1  - critical illness
YR  - 2015
SP  - 35
AB  - <p>Transfusion of blood products should improve tissue oxygenation and reduce negative consequences of anaemia. At the same time, adverse effects of transfusion, such as infections, immunologic reactions and mistransfusion, could be deleterious. Most transfusion guidelines suggest look-ing at the combination of haemoglobin or haematocrit levels in addition to clinical signs in the decision making process for a blood transfusion. The problem with such indications is that the clinical evaluation may be misleading in severely ill patients and haemoglobin levels that impair oxy-gen delivery cannot be determined easily. Many studies attempted to establish more convenient parameters, such as oxygen saturation from mixed and central ve-nous blood, tissue oxygen extraction and other methods. Although the results from these studies are conflicting, it appears that global oxygenation parameters are a good indicator for a blood transfusion in some categories of critically ill patients.</p>