RT  - Signa Vitae
ID  - 10.22514/SV151.042019.6
T1  - Using age, arterial lactate level and sequential organ failure assessment score in risk stratification of sepsis syndromes
A1  - AMR ELMORSI
A1  - AMR DAHROUG
A1  - ENAL FAHMY
A1  - ISLAM AHMED
K1  - Emergency
K1  - Critical
K1  - Sepsis
K1  - SOFA
K1  - Arterial Lactate
K1  - Stratification
YR  - 2019
SP  - 46
AB  - <p>Introduction: In low income countries, ICU places are limited and not all sepsis patients will benefit from ICU admission. Stratification is an important step to iden-tify patients who require ICU treatment from patients who can be treated on gen-eral ward setting. Improper stratification results in increased length of stay, costs, morbidity and mortality. Objective: The aim of this study was to stratify the risk of mortality in patients with sepsis syn-drome using age, arterial lactate level and SOFA score. Methods: In this prospective observational study, 250 patients with sepsis were enrolled and followed up un-til discharge. They were categorized into 2 groups according to 7-days mortality. Re-sults: SOFA score (≥5) was the only good tool (AUC=0.722) while age (≥65 years) (AUC=0.650) and arterial lactate (≥3.25 mmol/L) (0.690) were fair tools to predict 7-days mortality. A new score “ALSOFA score” (≥10) was an excellent tool for pre-diction (AUC =0.912, 95%CI: 0.851 to 0.940, p&lt;0.0001). It showed an excellent sensitivity (90.9%) and specificity (85.1%). Conclusion: In critically ill patients with sepsis syndromes, age, arterial lactate and SOFA score are fair tools of stratification. No single marker/score can be used alone to stratify such patients.</p>