Hospitals are critical infrastructures that must remain operational during disasters, yet they often become disaster targets themselves. This study offers a global retrospective analysis of hospital disasters from 1976 to 2023, drawing on data from the Emergency Events Database (EM-DAT). Our methodology combines a historical data review with an evaluation of the impact of technological advancements, community awareness, governmental policies, and psychological support mechanisms on disaster mitigation. By categorizing disasters into collapses, explosions, and fires, we specifically examine incidents leading to significant human casualties and property damage. This retrospective study employs quantitative analysis to identify trends and patterns in hospital disasters, utilizing statistical methods to assess data categorization by EM-DAT and to evaluate the frequency, severity and geographical disparities of these incidents. A notable increase in hospital fires highlights an urgent need for improved safety standards and preparedness. Our analysis also reveals significant regional differences in hospital safety protocols, advocating for tailored preparedness strategies. Enhanced safety standards and disaster preparedness within healthcare facilities are imperative. We propose the development of comprehensive, region-specific preparedness strategies, informed by our findings, to mitigate the impact of future hospital disasters. Addressing these challenges necessitates a global, collaborative approach, emphasizing the role of international cooperation in fostering safer healthcare environments.