Article Data

  • Views 967
  • Dowloads 125

Review

Open Access

Be careful what you eat and drink; Coprinic and Kounis syndrome in a patient with the Samter`s triad

  • JOAQUÍN VALLE ALONSO1
  • ELISA LOPERA LOPERA1
  • YELDA HERNÁNDEZ MONTES1
  • CARMEN NAVARRO2
  • PEDRO CEBALLOS GARCÍA1
  • JOSÉ TEJEDA1

1Department of Emergency Medicine, Hospital Valle de los Pedroches

2Department of Cardiology, Hospital Valle de los pedroches

DOI: 10.22514/SV101.042015.15 Vol.10,Issue 1,April 2015 pp.136-143

Published: 30 April 2015

*Corresponding Author(s): JOAQUÍN VALLE ALONSO E-mail: joa51274@hotmail.com

Abstract

Allergic reactions to chemicals, food products or even insect bites are encountered all over the world with a variety of manifestations. Symptoms range from the development of a minor rash to life threatening anaphylactic reactions. Sometimes, acute coronary syndrome (ACS) can be registered in such patients, which may have a serious impact on the course and management of the allergic reaction. Mushroom poisoning constitutes the main portion of plant toxicities in Spain. Depending on the type of mushroom, the adverse effects range from mild gastrointestinal (GI) symptoms to major cytotoxic effects resulting in organ failure and death. Coprinopsis atramentaria poisoning is rare but with serious consequences. We report a case of a 27 year old patient with a previous history of mild persistent asthma, nasal polyps and aspirin allergy that arrived to the Emergency Department with dizziness and temor after consuming beer at a party. On arrival to the hospital, the patient suddenly collapsed, with an electrocardiogram (ECG) showing ST elevation in the inferior leads and 3rd degree atrioventricular (AV) block accompanied by urticarial-like lesions. After administration of treatment, the patient and ECG abnormalities improved. A detailed medical history showed that the patient had eaten scrambled mushrooms and beer. Expert analysis demonstrated that the combined consumption of Coprinopsis atramentaria and alcoholic beverages produced a disulfiram-like reaction (Coprinic syndrome) and type I Kounis syndrome. No case like this has been previously reported.

Keywords

Kounis syndrome, Coreopsis atramentaria, acute coronary syndrome

Cite and Share

JOAQUÍN VALLE ALONSO,ELISA LOPERA LOPERA,YELDA HERNÁNDEZ MONTES,CARMEN NAVARRO,PEDRO CEBALLOS GARCÍA,JOSÉ TEJEDA. Be careful what you eat and drink; Coprinic and Kounis syndrome in a patient with the Samter`s triad. Signa Vitae. 2015. 10(1);136-143.

References

1. Goldfrank, LR. Mushrooms. In: Nelson LS, Lewin NA, Howland MA, Hoffman RS, Goldfrank LR, Flomenbaum NE, editor. Goldfrank’s Toxicologic Emergencies. 9th ed. New York: McGraw Hill; 2010. p. 1522.

2. Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH, Giffin SL. 2008 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 26th Annual Report. Clin Toxicol (Phila) 2009;47:911.

3. Brent, J, Palmer, RB. Mushrooms. In: Shannon, MW, Borron, SW, Burns MJ, editors. Haddad and Winchester’s Clinical Management of Poisoning and Drug Overdose. 4th ed. Philadelphia (PA): Saunders Elsevier; 2007. p. 455.

4. Michelot D. Poisoning by Coprinus atramentarius. Nat Toxins 1992;1:73.

5. Haberl B, Pfab R, Berndt S, Greifenhagen C, Zilker T. Case series: Alcohol intolerance with Coprine-like syndrome after consumption of the mushroom Lepiota aspera (Pers.:Fr.) Quél., 1886 (Freckled Dapperling). Clin Toxicol (Phila) 2011;49:113.

6. Pfister CW, Plice SG. Acute myocardial infarction during a prolonged allergic reaction to penicillin. Am Heart J 1950;40:945–7.

7. Kounis NG, Zavras GM. Histamine-induced coronary artery spasm: the concept of allergic angina. Br J Clin Pract 1991;45:121–8.

8. Kounis NG, Zavras GM. Allergic angina and allergic myocardial infarction. Circulation 1996;94:1789.

9. Yanagawa Y, Nishi K, Tomiharu N, Kawaguchi T. A case of takotsubo cardiomyopathy associated with Kounis syndrome. Int J Cardiol 2009;132:65-7.

10. Kounis GN, Kounis SA, Hahalis G, Kounis NG. Coronary artery spasm associated with eosinophilia: another manifestation of Kounis syndrome? Heart Lung Circ 2009;18:163-4.

11. Nikolaidis LA, Kounis NG, Grandman AH. Allergic angina and allergic

myocardial infarction: a new twist on an old syndrome. Can J Cardiol 2002;18:508–11.

12. Biteker M. A new classification of Kounis syndrome. Int J Cardiol 2010;145:553.

13. Cevik C, Nugent K, Shome GP, Kounis NG. Treatment of Kounis syndrome. Int J Cardiol 2010;143(3):223–6.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.

IndexCopernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.

Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.

Scopus: CiteScore 0.5(2021) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.

Submission Turnaround Time

Conferences

Top