Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

Signa Vitae (SV) is a peer-reviewed, open-access journal that aims be an unbiased and permanent forum for the fields of emergency medicine, intensive care medicine, anesthesia and pain medicine. It focuses on the latest research advances in these fields, including Disease prevention, diagnose, treatment and prognosis, Disease etiology, pathophysiology, and molecular mechanisms, Health care, Medical personnel health, Facilities and equipment, Teaching and training, Organization and management, Information and techniques, Drug application, etc. As a tool for easier and more effective experiences and science sharing, SV aims to provide professionals dedicated to all these relevant fields with cutting-edge techniques and information.


Open Access

Extracorporeal membrane oxygenation for refractory septic shock in children

Yufan Yang,Xiangni Wang,Jiaotian Huang,Xiulan Lu,Zhenghui Xiao

DOI: 10.22514/sv.2024.051

Abstract ( 555 ) PDF (820.48 kB) ( 142 ) Full Text

Open Access

The role of Asprosin in the diagnosis of diabetic and non-diabetic patients with sepsis

Semra Aytürk Salt,Nurettin Aydoğdu,Ömer Salt,Nihayet Fırat,Necdet Süt

DOI: 10.22514/sv.2024.056

Abstract ( 540 ) PDF (192.15 kB) ( 140 ) Full Text

Open Access

The epidemiology of poisoning and overdose in Saudi Arabia: exposures, risks, management and outcomes

Bader Alyahya,Musa Alfaifi,Abdulaziz Alalshaikh,Mohammed Arafat,Abdulrahman Aldhabib,Abdulaziz Al Hosaini,Ali Alsultan,Amash Al Harbi,Reem Alwaibah,Ghada Alajmi,Muath Alhumud,Mohammed Alswoaiegh,Abdulrahman Altalasi,Saad Alhaddab,Ghaida Almutairi,Maria Zadah,Nawfal Aljerian

DOI: 10.22514/sv.2024.035

Abstract ( 898 ) PDF (6.12 MB) ( 165 ) Full Text

Open Access

Factors associated with psychological distress in emergency medicine residents: findings from a single-center study

Tareq A. Al-Salamah,Fathima F. Farook,AbdulAziz AlKanhal,Amer Almutairi,Mohammad AlGhofili,AbdulRahman Banaeem

DOI: 10.22514/sv.2024.060

Abstract ( 544 ) PDF (427.61 kB) ( 122 ) Full Text

Published Ahead of Print

Open Access

The role of test results in the emergency department in the evaluation of major torso injury patients

Chun-Chih Cheng,Shih-Ching Kang,Pei-Hua Li,Chien-Hung Liao,Chi-Hsun Hsieh,Yu-Chi Kuo,Ting-An Hsu,Chih-Yuan Fu

Online publish date: 15 May 2024

DOI: 10.22514/sv.2024.064

Abstract ( 255 ) PDF (3.63 MB) ( 119 ) Full Text

Open Access Special Issue

Enhancing EMS readiness: a pilot evaluation of CPR proficiency and training dynamics among paramedics in Poland

Łukasz Maciejewski,Katarzyna Naylor,Konrad Szast,Ahmed M. Al-Wathinani,Mohammed Aljuaid,Krzysztof Goniewicz

Online publish date: 14 May 2024

DOI: 10.22514/sv.2024.063

(This article belongs to the Special Issue Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research)

Abstract ( 442 ) PDF (562.47 kB) ( 125 ) Full Text

Open Access

Application of opioid-free general anesthesia in laparoscopy: a meta-analysis of randomized controlled studies

Mei-hui Gao,Jin Meng,Xu-ming Hu,Jie Liu

Online publish date: 26 April 2024

DOI: 10.22514/sv.2024.050

Abstract ( 543 ) PDF (7.52 MB) ( 112 ) Full Text

Open Access

Success of the emergency physician to recognize pathological diffusion-weighted magnetic resonance imaging in acute stroke patients

Mehmet Nuri Bozdemir,Mehmet Uynaz,Ahmet Celik,Bulent Cekic,Mehmet Berk Eyinc,Mehmet Akcimen

Online publish date: 23 April 2024

DOI: 10.22514/sv.2024.048

Abstract ( 759 ) PDF (424.77 kB) ( 120 ) Full Text

Open Access

Sympathetic nerve entrapment point injection for intractable nausea and vomiting in pregnancy: a case report

Sungwoo Choi,Kangho Kim,Sangun Nah,Sechan Kim,Sangsoo Han

Online publish date: 19 December 2023

DOI: 10.22514/sv.2023.122

Abstract ( 1599 ) PDF (975.22 kB) ( 161 ) Full Text

Special Issues

Special issue title:

Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research

Keywords: Emergency Medical Services; Interdisciplinary Research in EMS; Pre-hospital Care Technologies; Crisis Management in Healthcare; Psychological Aspects of EMS; Public Health and Emergency Services

Editor: Prof. Dr. Krzysztof Goniewicz, PhD,Prof. Dr. Ahmed M. Al-Wathinani, PhD

Submission deadline: 28 February 2025

Special issue title:

AI Horizons: Revolutionizing Anesthesia, Critical Care, and Pain Medicine

Keywords: Anesthesia; Critical Care Medicine; Pain Medicine; Artificial Intelligence; Large Language Models; Natural Language Processing; Big Data; Data Science; Machine Learning

Editor: Prof. Marco Cascella

Submission deadline: 31 December 2024

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 December 2023

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 30 November 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Special issue title:

21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care

Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens

Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA

Submission deadline: 27 May 2022

Special issue title:

Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021

Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome

Editor: Prof. Won Young Kim, MD, PhD

Submission deadline: 01 June 2022

Special issue title:

Spinal Cord Injury

Keywords: Spinal cord injury (SCI), Damage mechanisms, Primary and secondary medullary lesions, Neurorehabilitation, Neurorestoration

Editor: Lecturer dr. Constantin Munteanu, PhD,Prof. Dr. Gelu Onose,Associate Prof. Dr. Mariana Rotariu, PhD,Assistant Prof. Dr. Gabriela Dogaru, PhD,Associate Prof. Dr. Elena Valentiana IONESCU, PhD,Assistant Prof. Dr. Cristina Daia, PhD

Submission deadline: 31 March 2022

Special issue title:

Outcome Measures and Assessment Tools in Spinal Cord Injury

Keywords: Spinal Cord Injury, Rehabilitation, Assessment Tools

Editor: Dr. Giovanni Galeoto

Submission deadline: 10 December 2021

To Be a Reviewer

If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

Review for SV

Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

Join Editorial Board


Prof. Giovanni Landoni, MD

Prof Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals.