Aims and scope

The aim of Signa Vitae (SV) is to be an unbiased and permanent forum for clinical anesthesia, intensive care, emergency and pain medicine. It serves professionals dedicated to all these relevant fields, as a tool for easier and more effective experiences and science sharing, with the ultimate goal to improve patients’ outcome. The scope of Signa Vitae is broad. It encompasses all aspects of clinical practice and fundamental research at the basis of anesthesia, intensive care, emergency and pain medicine, both in children and adults. It will better inform and educate the global scientific and medical community on the advancements in the fields at the basis of survival and a better quality of life, as stated in the appealing Latin version of its name: "Signs of life". 


Open Access

How challenges made us stronger

Giustino Varrassi

DOI: 10.22514/sv.2022.001

Abstract ( 313 ) PDF (300.47 KB) ( 153 )

Open Access Special Issue

From preclinical to clinical models of acute respiratory distress syndrome

Ruoyang Zhai,Woodys Lenga Ma Bonda,Gustavo Matute-Bello,Matthieu Jabaudon

DOI: 10.22514/sv.2021.228

Abstract ( 693 ) PDF (968.05 KB) ( 203 )

Open Access Special Issue

Herding cats: ethics in prehospital triage

Hasan Erbay

DOI: 10.22514/sv.2021.056

Abstract ( 1018 ) PDF (206.08 KB) ( 221 )

Open Access Special Issue

Machine learning techniques as an efficient alternative diagnostic tool for COVID-19 cases

Nicolás Bustos,Manuel Tello,Guillermo Droppelmann,Nicolás García,Felipe Feijoo,Víctor Leiva

DOI: 10.22514/sv.2021.110

Abstract ( 1744 ) PDF (6.72 MB) ( 341 )

Open Access

Prevention of temporary emergency medical center closure through isolation zone and screening triage in COVID-19 outbreak

Sin-Youl Park,Kyung Woo Lee,Suk Hee Lee,Jong Kun Kim,Jae Wan Cho,Jae Cheon Jeon,Jae Chul Cho

DOI: 10.22514/sv.2021.111

Abstract ( 610 ) PDF (697.15 KB) ( 173 )

Open Access

Quality of life and psychological assessment in patients with Fibromyalgia Syndrome during COVID-19 pandemic in Italy: prospective observational study

Vittorio Schweiger,Erica Secchettin,Giovanni Perini,Alvise Martini,Katia Donadello,Leonardo Gottin,Giovanna Del Balzo,Giustino Varrassi,Enrico Polati

DOI: 10.22514/sv.2021.127

Abstract ( 682 ) PDF (186.85 KB) ( 195 )

Open Access Special Issue

Factors associated with readmission to the Emergency Department in a cohort of COVID-19 hospitalized patients

Álvaro Romero-Duarte,Mario Rivera-Izquierdo,Antonio Jesús Láinez-Ramos-Bossini,Pablo Redruello-Guerrero,Antonio Cárdenas-Cruz

DOI: 10.22514/sv.2021.106

Abstract ( 660 ) PDF (646.93 KB) ( 167 )

Open Access Special Issue

Diagnostic accuracy of bedside ultrasonography in COVID-19 suspected patients admitted to the emergency department

Ramazan Guven,Ramazan Unal,Burcu Genc Yavuz,Ertugrul Ak,Gokhan Eyupoglu,Salih Fettahoglu,Basar Cander

DOI: 10.22514/sv.2021.116

Abstract ( 628 ) PDF (861.51 KB) ( 167 )

Open Access

COVID-19 pharmacy student perceptions: pharmacists' impact during the COVID-19 pandemic

Bryan Zhang,Justina Refela,Frank Breve,Peter Magnusson,Joseph Pergolizzi

DOI: 10.22514/sv.2021.208

Abstract ( 1081 ) PDF (175.69 KB) ( 157 )

Open Access

Topical 5% lidocaine patches for treating postherpetic neuralgia: a survey among nurses and patients

Joseph V. Pergolizzi Jr.,Sri Nalamachu,Kailyn Mitchell,Antonella Paladini,Robert Taylor Jr.,Giustino Varrassi

DOI: 10.22514/sv.2021.114

Abstract ( 725 ) PDF (983.4 KB) ( 170 )

Open Access

Computed tomography for patients with drug- or substance-induced seizures: a retrospective analysis

Shao-Feng Liao,Ming-Nan Huang,Cheng-Hsien Hsieh,Chun-Kuei Chen,Po-Cheng Chen,Chen-June Seak,Hsien-Yi Chen

DOI: 10.22514/sv.2021.117

Abstract ( 553 ) PDF (321.25 KB) ( 155 )

Open Access

The effectiveness of the cadaver-based educational seminar for trauma surgery (C-BEST) for residents

Hiroshi Homma,Jun Oda,Hidefumi Sano,Shinichi Kawata,Masahiro Itoh

DOI: 10.22514/sv.2021.140

Abstract ( 498 ) PDF (1.11 MB) ( 159 )

Open Access

Clinical features of isolated superior mesenteric artery dissection in the emergency department: a single center retrospective study

Xiang-Min Li,Guo-Qing Huang,Li-Ping Zhou,Xiao-Ye Mo,Ai-Min Wang,Fang-Jie Zhang

DOI: 10.22514/sv.2021.225

Abstract ( 390 ) PDF (3.35 MB) ( 141 )

Open Access

Acute heart failure from a rapidly progressing large tumor in the right atrium

I-Hsin Chang,Lian-Jie Lin,Ren-Chieh Wu

DOI: 10.22514/sv.2021.095

Abstract ( 595 ) PDF (1.65 MB) ( 149 )

Open Access

Angel or devil? Speech disorder after dexamethasone injection for sore throat

Sarper Yilmaz,Ozgur Karcioglu,Rohat Ak,Nihat Mujdat Hokenek

DOI: 10.22514/sv.2021.123

Abstract ( 627 ) PDF (165.65 KB) ( 154 )

Published Ahead of Print

Open Access

Dexmedetomidine versus fentanyl on stress response and pain control in adult patients undergoing laparoscopic surgery

Marian Greiss,Bassem Boulos Ghobrial,Waleed Mohamed Abd Elmageed,Dalia Mahmoud Elfawy,Raham Hasan Mostafa

Online publish date: 20 January 2022

DOI: 10.22514/sv.2022.007

Abstract ( 200 ) PDF (2.49 MB) ( 134 )

Open Access

Nonspecific abdominal pain: Do I have to allocate a specific diagnosis for every patient?

Ozgur Karcioglu

Online publish date: 13 January 2022

DOI: 10.22514/sv.2022.005

Abstract ( 308 ) PDF (160.24 KB) ( 151 )

Open Access Special Issue

Impact of the COVID-19 pandemic on osteoporotic vertebral fracture incidence and follow-up at the emergency department. A retrospective study of a tertiary hospital in southern Spain

Antonio J. Láinez Ramos-Bossini,Bárbara Láinez Millán,Fernando Ruiz Santiago,Mario Rivera-Izquierdo

Online publish date: 05 January 2022

DOI: 10.22514/sv.2022.002

Abstract ( 256 ) PDF (384.67 KB) ( 149 )

Special Issues

Special issue title:

Sex-related differences in peri-operative and in critically ill patients

Keywords: Sex and gender differences, Peri-operative patients, Critically ill patients, Emergency department, Intensive care unit

Editor: Prof. Giovanni Landoni, MD

Submission deadline: 09 June 2022

Special issue title:

Impact of COVID-19 on Dentistry

Keywords: COVID-19, dental practice, dental education, infection control, clinical practice, dental operatory, dental profession

Editor: Dr. Sreekanth Kumar Mallineni

Submission deadline: 30 March 2022

Special issue title:

Advances in critical emergency medicine during COVID19 pandemic

Keywords: critical emergency medicine, covid19, ARDS, artificial intelligence, triage

Editor: George Karlis

Submission deadline: 25 October 2022

Special issue title:

Emergency Management of Polytrauma

Keywords: Polytrauma, Trauma, Emergency management, Golden hour, Advanced Trauma Life Support, ABCDE approach, Airway management, cervical spine protection, Glasgow coma scale, hemorrhage, trauma team, survey and management

Editor: Naresh Kaul, MBBS, MD, FICA

Submission deadline: 30 September 2022

Special issue title:

Postoperative analgesia for spine surgery

Keywords: spine surgery, postoperative pain management, multimodal analgesia, opioid, erector spinae plane block, retrolaminar block

Editor: Prof. Joho Tokumine, MD, PhD

Submission deadline: 30 September 2022

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 11 March 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Inter-Professional Teamwork Challenges - intensive care of preterm infants

Keywords: preterm infants, respiratory distress syndrome, severe infection, necrotizing enterocolitis, bronchopulmonary dysplasia, extrauterine growth retardation, hemorrhagic-ischemic cerebral injury, milk protein allergy

Editor: Jinrong Li, MD, PhD,Li-Na Qiao, MD, PhD,Jing Shi, MD, PhD

Submission deadline: 09 June 2022

Special issue title:

Neurocritical care in pandemic and beyond

Keywords: Neurocritical Care, Stroke, Neurotrauma

Editor: Luis Rafael Moscote- Salazar, MD ,Tariq Janjua, MD

Submission deadline: 01 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Featured Article

A Novel Objective Approach Towards Physicians' Knowledge and Practice Patterns to Optimize Central Venous Catheter Placement: A Cross-sectional Study. DOI: 10.22514/sv.2020.16.0052

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You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (both editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Giustino Varrassi

Professor Giustino Varrassi, MD, PhD is Professor and former Chairman of the Department of Anesthesia and Pain Medicine, University of L'Aquila, Italy. At the moment, he is president of the Paolo Procacci Foundation, Roma, Italy. His scientific interest is mainly in Pain Medicine as shown by the many initiatives he has organized in his career: Founding Member (1993) and Past-President of the European Pain Federation (EFIC), where he has served in the Executive Board for 21 years; Past-President of the Italian Association for the Study of Pain, where he has served in the Council for over 30 years. In these positions, he has organized over 40 international and national congresses. Moreover, he has an intense publishing activity on Pain Medicine and other aspects of his medical specialty. More recently, he has joined NEMA Research Group. as Senior Consultant.