Signa Vitae
Print ISSN: 1334-5605 | Online ISSN: 1845-206X
Official journal of the International Women in Intensive and critical care Network (iWIN, https://www.iwinideal.com/home/)
Signa Vitae (SV) is a peer-reviewed, open-access journal whose Latin name means “Signs of Life.” It serves as an unbiased and permanent forum for Emergency Medicine, Intensive Care Medicine, Anesthesia and Pain Medicine, dedicated to the recognition, monitoring, intervention, nursing, and improvement of vital signs. The journal places particular emphasis on acute conditions requiring immediate intervention to stabilize vital signs, as well as various traumas and injuries; critical conditions; anesthetic techniques, pharmacological agents, monitoring, perioperative management and associated complications; and multimodal assessment and treatment of pain (with emphasis on acute/critical/perioperative pain, while also covering severe chronic pain).
The journal welcomes submissions of research closely related to the above fields, including risk factors, etiology, pathophysiology and molecular mechanisms of diseases, prognostic assessment and outcome improvement, disease management, healthcare professionals’ well-being (e.g., psychological stress, burnout, etc.), facilities and equipment, education and training (including simulation), and others—especially manuscripts with practical impact on patient vital sign stabilization, clinical practice, or medical care quality.
Articles
Shortening the path to perfusion: why every link in the chain of survival shapes ECPR outcomes
Shortening the path to perfusion: why every link in the chain of survival shapes ECPR outcomes
DOI: 10.22514/sv.2026.022
Are emergency departments useful for quitting smoking? A narrative review
Are emergency departments useful for quitting smoking? A narrative review
DOI: 10.22514/sv.2026.008
Continuous renal replacement therapy and neurological dysfunction in septic acute kidney injury
Continuous renal replacement therapy and neurological dysfunction in septic acute kidney injury
DOI: 10.22514/sv.2026.028
Dose of continuous renal replacement therapy for acute kidney injury in critically ill patients
Dose of continuous renal replacement therapy for acute kidney injury in critically ill patients
DOI: 10.22514/sv.2026.029
Approach to and management of acute diarrhea in adults in the emergency department setting
Approach to and management of acute diarrhea in adults in the emergency department setting
DOI: 10.22514/sv.2026.030
Blind caudal epidural injection for sciatica in resource-limited practice: a narrative review
Blind caudal epidural injection for sciatica in resource-limited practice: a narrative review
DOI: 10.22514/sv.2026.024
Early non-invasive ventilation for the management of patients with acute respiratory failure: a systematic review and meta-analysis
Early non-invasive ventilation for the management of patients with acute respiratory failure: a systematic review and meta-analysis
DOI: 10.22514/sv.2026.025
Impact of the interval between cardiopulmonary resuscitation and veno-arterial extracorporeal membrane oxygenation on in-hospital mortality in adult patients after cardiac arrest
Impact of the interval between cardiopulmonary resuscitation and veno-arterial extracorporeal membrane oxygenation on in-hospital mortality in adult patients after cardiac arrest
DOI: 10.22514/sv.2025.197
Epidemiological and clinical characteristics of acute ischemic stroke patients in a war zone
Epidemiological and clinical characteristics of acute ischemic stroke patients in a war zone
DOI: 10.22514/sv.2026.020
Impact of tranexamic acid on intraoperative fluid intake in patients undergoing posterior spine fixation: a retrospective cohort study
Impact of tranexamic acid on intraoperative fluid intake in patients undergoing posterior spine fixation: a retrospective cohort study
DOI: 10.22514/sv.2026.021
Early management of out-of-hospital respiratory distress: an interdisciplinary consensus guidance
Early management of out-of-hospital respiratory distress: an interdisciplinary consensus guidance
DOI: 10.22514/sv.2026.023
The association of temperature, humidity, pressure, air pollution and dusty days with emergency department visits for upper respiratory complaints
The association of temperature, humidity, pressure, air pollution and dusty days with emergency department visits for upper respiratory complaints
DOI: 10.22514/sv.2026.031
Effect of rescuer–dispatcher communication on chest compression quality during simulated cardiac arrest
Effect of rescuer–dispatcher communication on chest compression quality during simulated cardiac arrest
DOI: 10.22514/sv.2026.032
Prognostic utility of the inflammatory burden index for early mortality prediction in heart failure: a retrospective cohort study using the MIMIC-IV database
Prognostic utility of the inflammatory burden index for early mortality prediction in heart failure: a retrospective cohort study using the MIMIC-IV database
DOI: 10.22514/sv.2026.033
A simplified formula for rapid dilution of catecholamines in initial emergency and critical care resuscitation
A simplified formula for rapid dilution of catecholamines in initial emergency and critical care resuscitation
DOI: 10.22514/sv.2026.026
Correction: Application of damage control orthopaedics in treatment of massive hemorrhage in severe traumatic fractures
Correction: Application of damage control orthopaedics in treatment of massive hemorrhage in severe traumatic fractures
DOI: 10.22514/sv.2026.034
Correction: The effects of perioperative low-dose magnesium sulfate infusion on postoperative pain in lumbar surgery
Correction: The effects of perioperative low-dose magnesium sulfate infusion on postoperative pain in lumbar surgery
DOI: 10.22514/sv.2026.035
Correction: Emergency treatment for iatrogenic lumbar arterial injury occurred during posterior lumbar interbody fusion: a case report
Correction: Emergency treatment for iatrogenic lumbar arterial injury occurred during posterior lumbar interbody fusion: a case report
DOI: 10.22514/sv.2026.036
Correction: An early presentation of neurogenic pulmonary edema in acute subarachnoid hemorrhage
Correction: An early presentation of neurogenic pulmonary edema in acute subarachnoid hemorrhage
DOI: 10.22514/sv.2026.037
Correction: Recognizing the usage of analgesics among Saudi women with primary dysmenorrhea
Correction: Recognizing the usage of analgesics among Saudi women with primary dysmenorrhea
DOI: 10.22514/sv.2026.038
Correction: Ursolic acid inhibits NLRP3 inflammasome activation and alleviates vascular smooth muscle injury in Kawasaki disease
Correction: Ursolic acid inhibits NLRP3 inflammasome activation and alleviates vascular smooth muscle injury in Kawasaki disease
DOI: 10.22514/sv.2026.039
Correction: Efficacy observation of erythropoietin on sepsis complicated with acute respiratory distress syndrome
Correction: Efficacy observation of erythropoietin on sepsis complicated with acute respiratory distress syndrome
DOI: 10.22514/sv.2026.040
Correction: The role of Asprosin in the diagnosis of diabetic and non-diabetic patients with sepsis
Correction: The role of Asprosin in the diagnosis of diabetic and non-diabetic patients with sepsis
DOI: 10.22514/sv.2026.041
Correction: Curcumin exerts anti-inflammatory, antioxidant and anti-ferroptotic effects through the Nrf2/HO-1 pathway to protect cardiomyocytes against sepsis
Correction: Curcumin exerts anti-inflammatory, antioxidant and anti-ferroptotic effects through the Nrf2/HO-1 pathway to protect cardiomyocytes against sepsis
DOI: 10.22514/sv.2026.042
Correction: Effects of immediate and delayed infusion of residual physical blood on coagulation function, intraoperative bleeding, and hemostasis time in aortic dissection surgery under cardiopulmonary bypass
Correction: Effects of immediate and delayed infusion of residual physical blood on coagulation function, intraoperative bleeding, and hemostasis time in aortic dissection surgery under cardiopulmonary bypass
DOI: 10.22514/sv.2026.043
Correction: Enhancing EMS readiness: a pilot evaluation of CPR proficiency and training dynamics among paramedics in Poland
Correction: Enhancing EMS readiness: a pilot evaluation of CPR proficiency and training dynamics among paramedics in Poland
DOI: 10.22514/sv.2026.044
Correction: Angioembolization for geriatric stable pelvic fracture with active bleeding—the possibility of massive hemorrhage due to corona mortis
Correction: Angioembolization for geriatric stable pelvic fracture with active bleeding—the possibility of massive hemorrhage due to corona mortis
DOI: 10.22514/sv.2026.046
Correction: Risk factors of post-intubation hypotension in severe pneumonia patients
Correction: Risk factors of post-intubation hypotension in severe pneumonia patients
DOI: 10.22514/sv.2026.047
Correction: Moscatilin inhibits sevoflurane-induced inflammatory and oxidative stress injury in hippocampal neuronal HT22 cells
Correction: Moscatilin inhibits sevoflurane-induced inflammatory and oxidative stress injury in hippocampal neuronal HT22 cells
DOI: 10.22514/sv.2026.048
Published Ahead of Print
Characteristics, etiologies and outcomes of cardiac arrest in the emergency department
Characteristics, etiologies and outcomes of cardiac arrest in the emergency department
Online publish date: 06 January 2026
DOI: 10.22514/sv.2026.001
Health disparities in emergency department patients with severe mental illness and non-traumatic hollow organ perforation
Health disparities in emergency department patients with severe mental illness and non-traumatic hollow organ perforation
Online publish date: 11 December 2025
DOI: 10.22514/sv.2025.196
Measurement of the diameter and area of the inferior vena cava using computed tomography and its relationship with intravascular volume
Measurement of the diameter and area of the inferior vena cava using computed tomography and its relationship with intravascular volume
Online publish date: 30 October 2025
DOI: 10.22514/sv.2025.164
QT interval prolongation during carbon monoxide poisoning is a predictor of late cardiac and neurological complications
QT interval prolongation during carbon monoxide poisoning is a predictor of late cardiac and neurological complications
Online publish date: 13 October 2025
DOI: 10.22514/sv.2025.154
Special Issues
Acute Trauma: Immediate Interventions, Long-Term Impacts, Advancements, and Medico-legal Evaluation
Keywords: EMS; Trauma Management; Healthcare System Preparedness; Medico-Legal Evaluation
Editor: Prof. Dr. Giuseppe Basile, MD, Dr. Luca Bianco Prevot, MD, Dr. Vittorio Bolcato, MD
Submission deadline: 31 July 2026
Advances in the Diagnosis and Management of Sepsis and Septic Shock
Keywords: Diagnosis; Management; Sepsis; Septic Shock; Lactate Hypotension; Vasopressors
Editor: Prof. Dr. Ozgur Karcioglu, MD, Assoc. Prof. Dr. Feride Sinem AKGUN, MD, Assist. Prof. Dr. Betul AKBUGA OZEL, MD
Submission deadline: 31 May 2027
2025 Annual Meeting of Taiwanese Society of Regional Anesthesia & Pain Management (TSRA-PM) in Conjunction with International Symposium of Regional Anesthesia Asia (RA Asia)
Keywords: Regional Anesthesia; Pain Medicine; Anatomy
Editor: Assoc. Prof. Dr. Jui-An Lin, MD, PhD, Assist. Prof. Dr. Kuo-Chuan Hung, MD, Enoch Yi-No Kang, Prof. Dr. Ke-Vin Chang, MD, PhD, CIPS, RMSK, ASRA-PMUC, Assoc. Prof. Dr. Wu Shao Chun, MD, Dr. Shang-Ru Yeoh, MD, MSc
Submission deadline: 01 August 2026
Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research
Keywords: Emergency Medical Services; Interdisciplinary Research in EMS; Pre-hospital Care Technologies; Crisis Management in Healthcare; Psychological Aspects of EMS; Public Health and Emergency Services
Editor: Prof. Dr. Krzysztof Goniewicz, PhD, Prof. Dr. Ahmed M. Al-Wathinani, PhD
Submission deadline: 28 February 2025
Advances in Obstetric Anaesthesia
Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia
Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA
Submission deadline: 31 December 2023
Cardiothoracic anaesthesia and intensive care: current challenges and novelties
Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges
Editor: Dr. Marko Zdravkovic, MD, PhD
Submission deadline: 30 November 2022
Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022
Keywords: Emergency medicine
Editor: Kyungwon Lee, MD, PhD, Young Duck Cho, MD, PhD
Submission deadline: 31 December 2022
Medical Simulation - success in education, future of science
Keywords: medical simulation, emergency medicine, medical education
Editor: Tomasz Kłosiewicz, MD, MSc, Mateusz Puślecki, PhD
Submission deadline: 31 December 2022
21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care
Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens
Editor: Dr. Ioanna Siafaka, MD, PhD, Dr. Maria Kokolaki, MD, PhD, Dr. Athina Vadalouca, MD, PhD, FIPP, Dr. Evmorfia Stavropoulou, MD, PhD, EDRA, Dr. Eleni Moka, MD, PhD, MSc, EDRA
Submission deadline: 27 May 2022
Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021
Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome
Editor: Prof. Won Young Kim, MD, PhD
Submission deadline: 01 June 2022
To Be a Reviewer
If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.
Join Editorial Board
You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.
Editor-in-Chief
Prof. Giovanni Landoni, MD
Prof Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals.