Aims and scope

The aim of Signa Vitae (SV) is to be an unbiased and permanent forum for clinical anesthesia, intensive care, emergency and pain medicine. It serves professionals dedicated to all these relevant fields, as a tool for easier and more effective experiences and science sharing, with the ultimate goal to improve patients’ outcome. The scope of Signa Vitae is broad. It encompasses all aspects of clinical practice and fundamental research at the basis of anesthesia, intensive care, emergency and pain medicine, both in children and adults. It will better inform and educate the global scientific and medical community on the advancements in the fields at the basis of survival and a better quality of life, as stated in the appealing Latin version of its name: "Signs of life". 


Open Access

Predictors of short- and long-term outcome after open cardiac surgery in a high-volume referral tertiary hospital: the role of surgical team caseload

Fabrizio Monaco,Gaia Barucco,Gabriele Valsecchi,Margherita Licheri,Elisa Nicelli,Elidodoro Cama,Marina Pieri,Giuseppe Dalessandro,Cristina Nakhnoukh,Carola Galbiati,Gabriele Sanchini,Camilla Biselli,Rosalba Lembo,Evgeny Fominskiy,IRCCS San Raffaele Scientific Institute

DOI: 10.22514/sv.2022.044

Abstract ( 636 ) PDF (224.61 kB) ( 156 ) Full Text

Open Access Special Issue

Is early surgical intervention effective for traumatic severe cervical spinal cord injury? A retrospective study secondary publication

Koji Yamamoto,Akinori Okuda,Naoki Maegawa,Hironobu Konishi,Keita Miyazaki,Yusuke Tada,Yohei Kogeichi,Keisuke Takano,Hideki Asai,Yasuyuki Kawai,Yasuyuki Urisono,Hideki Shigematsu,Kenji Kawamura,Hidetada Fukushima,Yasuhito Tanaka

DOI: 10.22514/sv.2021.256

(This article belongs to the Special Issue Spinal Cord Injury)

Abstract ( 738 ) PDF (323.03 kB) ( 167 ) Full Text

Open Access Special Issue

Effects of occupational anxiety on ethical value tendencies in emergency healthcare workers in Turkey


DOI: 10.22514/sv.2021.237

(This article belongs to the Special Issue Emergency Medicine and Ethics)

Abstract ( 1204 ) PDF (202.65 kB) ( 176 ) Full Text

Open Access

Epidemiological characteristics and initial clinical presentation of patients with laboratory-confirmed MERS-CoV infection in an emergency department

Zohair Al Aseri,Jaffar A. Al-Tawfiq,Mohammed Alnakhli,Abdullah AlNooh,Abdulaziz Alnassar,Salah Alkhalid,Abdulaziz Al Dughayman,Tariq Wani,Abdulkarim Alhetheel,Mazin Barry

DOI: 10.22514/sv.2021.251

Abstract ( 1031 ) PDF (201.71 kB) ( 158 ) Full Text

Open Access

The value of ultrasonography in predicting outcomes at an early school age among individuals with perinatal hypoxic-ischemic encephalopathy

Renata Dzikiene,Saulius Lukosevicius,Jurate Laurynaitiene,Vitalija Marmiene,Irena Nedzelskiene,Rasa Tameliene,Ausrele Kudreviciene

DOI: 10.22514/sv.2022.010

Abstract ( 760 ) PDF (2.4 MB) ( 148 ) Full Text

Published Ahead of Print

Open Access

Correlation between income changes in the elderly receiving the basic old-age pension and suicide rates

Sun Hwa Lee,Jong Seok Oh,Duk Hee Lee,Yun Hyung Choi,Ji Yeon Lim

Online publish date: 21 July 2022

DOI: 10.22514/sv.2022.057

Abstract ( 349 ) PDF (1.09 MB) ( 116 ) Full Text

Open Access

Effect of hypothermia and hyperthermia on all-cause in-hospital mortality in emergencies: a comprehensive nationwide analysis from the Republic of Korea

Hyuntack Shin,Jin Hee Jeong,Sang Bong Lee,Dae Sung Lim,Dong Hoon Kim,Ae Jin Sung

Online publish date: 21 July 2022

DOI: 10.22514/sv.2022.056

Abstract ( 351 ) PDF (5.69 MB) ( 123 ) Full Text

Open Access Special Issue

Respiratory infections and acute respiratory distress syndrome

Adrian Ceccato,Elena Campaña-Duel,Aina Areny-Balagueró,Saad Nseir,Antoni Torres

Online publish date: 20 July 2022

DOI: 10.22514/sv.2022.054

(This article belongs to the Special Issue New Insights in Acute Respiratory Distress Syndrome)

Abstract ( 367 ) PDF (213 kB) ( 153 ) Full Text

Open Access Special Issue

Evidence and rationale for vaccinating children and adolescents against SARS-CoV-2: a comprehensive narrative review

Nikolaos Karantaglis,Antonios Gkantaras,Despoina Iordanidou,Eleni Volakli,Eleni Karakeke,Maria Katsafiloudi,Asimina Violaki,Maria Sdougka

Online publish date: 20 July 2022

DOI: 10.22514/sv.2022.055

(This article belongs to the Special Issue Pediatric Critical Care)

Abstract ( 528 ) PDF (274.85 kB) ( 132 ) Full Text

Open Access

The prognostic value of laboratory parameters referring to hemopoietic stress in patients with COVID-19—a single center experience

István László,Mariann Berhés,Katalin Tisza,Zsófia Miltényi,Norbert Balázsfalvi,Attila Vaskó,László Asztalos,Attila Kertész,Ákos Fábián,János Kappelmayer,Béla Fülesdi

Online publish date: 18 July 2022

DOI: 10.22514/sv.2022.053

Abstract ( 379 ) PDF (1.66 MB) ( 145 ) Full Text

Open Access

Factors influencing length of hospital stay in patients using patient-controlled analgesia after laparotomy surgery-retrospective observational study

Hung-Chieh Chen,Yu-Huan Tsou,Chia-Kai Liu,Kuan-Hung Chen,Chien-Hui Yang

Online publish date: 18 July 2022

DOI: 10.22514/sv.2022.052

Abstract ( 354 ) PDF (1.13 MB) ( 123 ) Full Text

Special Issues

Special issue title:

Improving Survival from Cardiac Arrest: A Review of Current Practice and Challenges

Keywords: Cardiac Arrest; CPR; Resuscitation; OHCA; IHCA

Editor: Dr. Wachira Wongtanasarasin

Submission deadline: 30 September 2023

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 May 2023

Special issue title:

Nutrition in Critically Ill Patients

Keywords: Critically ill patient; Enteral nutrition; Parenteral nutrition; Micronutrients; Macronutrients

Editor: Prof. Dr. Mahmoud M. A. Abulmeaty, MD, FACN

Submission deadline: 31 March 2023

Special issue title:

Impact of COVID-19 on Dentistry

Keywords: COVID-19, dental practice, dental education, infection control, clinical practice, dental operatory, dental profession

Editor: Dr. Sreekanth Kumar Mallineni

Submission deadline: 30 September 2022

Special issue title:

Advances in critical emergency medicine during COVID19 pandemic

Keywords: critical emergency medicine, covid19, ARDS, artificial intelligence, triage

Editor: George Karlis

Submission deadline: 25 October 2022

Special issue title:

Emergency Management of Polytrauma

Keywords: Polytrauma, Trauma, Emergency management, Golden hour, Advanced Trauma Life Support, ABCDE approach, Airway management, cervical spine protection, Glasgow coma scale, hemorrhage, trauma team, survey and management

Editor: Naresh Kaul, MBBS, MD, FICA

Submission deadline: 30 September 2022

Special issue title:

Postoperative analgesia for spine surgery

Keywords: spine surgery, postoperative pain management, multimodal analgesia, opioid, erector spinae plane block, retrolaminar block

Editor: Prof. Joho Tokumine, MD, PhD

Submission deadline: 30 September 2022

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 31 October 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

To Be a Reviewer

If you would like to volunteer to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (both editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Prof. Giustino Varrassi, MD, PhD

Professor Giustino Varrassi, MD, PhD is Professor and former Chairman of the Department of Anesthesia and Pain Medicine, University of L'Aquila, Italy. At the moment, he is president of the Paolo Procacci Foundation, Roma, Italy. His scientific interest is mainly in Pain Medicine as shown by the many initiatives he has organized in his career: Founding Member (1993) and Past-President of the European Pain Federation (EFIC), where he has served in the Executive Board for 21 years; Past-President of the Italian Association for the Study of Pain, where he has served in the Council for over 30 years. In these positions, he has organized over 40 international and national congresses. Moreover, he has an intense publishing activity on Pain Medicine and other aspects of his medical specialty. More recently, he has joined NEMA Research Group. as Senior Consultant.