Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

The aim of Signa Vitae (SV) is to be an unbiased and permanent forum for clinical anesthesia, intensive care, emergency and pain medicine. It serves professionals dedicated to all these relevant fields, as a tool for easier and more effective experiences and science sharing, with the ultimate goal to improve patients’ outcome. The scope of Signa Vitae is broad. It encompasses all aspects of clinical practice and fundamental research at the basis of anesthesia, intensive care, emergency and pain medicine, both in children and adults. It will better inform and educate the global scientific and medical community on the advancements in the fields at the basis of survival and a better quality of life, as stated in the appealing Latin version of its name: "Signs of life".


Open Access Special Issue

Comparison of dexmedetomidine and lipophilic opioids as adjuvants to local anesthetics for epidural labor analgesia: a meta-analysis of randomized controlled trials

Shi-ke Yang,Min Liu,Jie Chen,Yuan-yuan Yang,Fang-zheng Zhuan,Wen-qun Sun,De-zhi Mao

DOI: 10.22514/sv.2021.242

(This article belongs to the Special Issue Opioid Free Analgesia: new concept, new trends)

Abstract ( 958 ) PDF (6.93 MB) ( 231 ) Full Text

Open Access

Sex-related mortality differences in young adult septic shock patients

Alberto Zangrillo,Federica Morselli,Emanuela Biagioni,Roberta Di Stella,Irene Coloretti,Elena Moizo,Valentina Paola Plumari,Giacomo Monti,Giovanni Borghi,Andrea Salonia,Giada Almirante,Davide Maraggia,Massimo Zambon,Nicola Langiano,Agostino Roasio,Laura Pasin,Milena Mucci,Paolo Federico Beccaria,Nicola Pasculli,Martina Baiardo Redaelli,Ottavia Pallanch,Giulia Gallo,Giovanni Real,Marta Nava,Sophie Venturelli,Martina Tosi,Elena Munari,Maria Grazia Visconti,Silvia Perno,Massimo Girardis,Giovanni Landoni

DOI: 10.22514/sv.2022.017

Abstract ( 1592 ) PDF (346.31 kB) ( 220 ) Full Text

Open Access

The effect of the addition of in-bed leg cycling using a MOTOmed device to standard rehabilitation on the length of mechanical ventilation: a randomized clinical trial

Jan Maca,Chwalkova Iva,Fiedorova Iva,Knapkova Lucie,Koci Marketa,Nytra Ivana,Kucerova Zuzana,Zoubkova Renata

DOI: 10.22514/sv.2022.024

Abstract ( 828 ) PDF (937.96 kB) ( 204 ) Full Text

Open Access

Complexity measures, an analysis for electromyography and its possible application to spinal cord injuries

Dragos Arotaritei,Mariana Rotariu,Mihai Ilea,Marius Turnea,Catalin Ionite,Iustina Condurache,Andrei Gheorghita

DOI: 10.22514/sv.2022.031

Abstract ( 1010 ) PDF (7.31 MB) ( 222 ) Full Text

Open Access

Decision-making and treatment results of complex proximal humeral fractures in geriatric patients: retrospective study from a level 1 trauma centre

Miha Ambrožič,Rok Bergman,Luka Hodnik,Roman Luštrik,Franc Štefanič,Matej Cimerman,Ladislav Kovačič

DOI: 10.22514/sv.2022.040

Abstract ( 818 ) PDF (5.04 MB) ( 172 ) Full Text

Open Access

Stress perception among dental practitioners in Saudi Arabia during the COVID-19 pandemic: a cross-sectional survey

Saquib Ahmed Shaikh,Sami Aldhuwayhi,Sreekanth Kumar Mallineni,Vinutha Kumari Varadharaju,Amar Ashok Thakare,Mohammed Ziauddeen Mustafa

DOI: 10.22514/sv.2022.042

Abstract ( 1264 ) PDF (2.22 MB) ( 199 ) Full Text

Open Access

Sudden cardiac death in excited delirium, and how to prevent it

Tina Čakš Golec,Rajko Kavalar,Igor Goričan,Matej Strnad

DOI: 10.22514/sv.2021.222

Abstract ( 1060 ) PDF (188.97 kB) ( 159 ) Full Text

Published Ahead of Print

Open Access Special Issue

Procedural sedation and analgesia in the pediatric intensive care unit

Ivana Budic,Vesna Marjanovic,Ivona Djordjevic,Marija Stevic,Dragoljub Zivanovic,Dusica Simic

Online publish date: 31 January 2023

DOI: 10.22514/sv.2023.007

(This article belongs to the Special Issue Pediatric Critical Care)

Abstract ( 190 ) PDF (209.25 kB) ( 156 ) Full Text

Open Access Special Issue

Acute abdomen in the emergency department: the emergency surgeon contribute "old is the new approach"

Carlos Macedo-Oliveira,Márcia Carvalho,Luís Madureira,Nuno Muralha

Online publish date: 31 January 2023

DOI: 10.22514/sv.2023.006

(This article belongs to the Special Issue Acute Abdomen in the Emergency Department: the Emergency Surgeon Contribute)

Abstract ( 193 ) PDF (175.45 kB) ( 134 ) Full Text

Open Access

Imbalanced salivary electrolytes, COVID-19 severity, and dysgeusia

Hanadi Abdullah Alwafi,Soad Shaker Ali,Sunil Babu Kotha,Layla Waleed Abuljadayel,Maha Ibrahim,Ibrahim Rashad Noor Elahi,Hebah Abdullah Alwafi,Matthew D. Finkelman,Nagla A. El-Shitany

Online publish date: 18 January 2023

DOI: 10.22514/sv.2023.005

Abstract ( 239 ) PDF (4.92 MB) ( 123 ) Full Text

Special Issues

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 May 2023

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 30 November 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Special issue title:

21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care

Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens

Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA

Submission deadline: 27 May 2022

Special issue title:

Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021

Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome

Editor: Prof. Won Young Kim, MD, PhD

Submission deadline: 01 June 2022

Special issue title:

Spinal Cord Injury

Keywords: Spinal cord injury (SCI), Damage mechanisms, Primary and secondary medullary lesions, Neurorehabilitation, Neurorestoration

Editor: Lecturer dr. Constantin Munteanu, PhD,Prof. Dr. Gelu Onose,Associate Prof. Dr. Mariana Rotariu, PhD,Assistant Prof. Dr. Gabriela Dogaru, PhD,Associate Prof. Dr. Elena Valentiana IONESCU, PhD,Assistant Prof. Dr. Cristina Daia, PhD

Submission deadline: 31 March 2022

Special issue title:

Outcome Measures and Assessment Tools in Spinal Cord Injury

Keywords: Spinal Cord Injury, Rehabilitation, Assessment Tools

Editor: Dr. Giovanni Galeoto

Submission deadline: 10 December 2021

Special issue title:

Opioid Free Analgesia: new concept, new trends

Keywords: Analgesia, Pain, Opioids, OFA, Regional block

Editor: Dr. Mohamed Adel Aboelela

Submission deadline: 01 April 2022

Special issue title:

Life-Threatening Clinical Situations in The Cardiac Intensive Care Unit

Keywords: Acute coronary syndrome, Cardiomyopathies, Cardiac arrhythmias, Conduction disorders, Valvular heart disease, Aortic dissection, Acute pulmonary thromboembolism

Editor: Dr. Larisa ANGHEL,Dr. Cristian STĂTESCU,Dr. Radu SASCĂU

Submission deadline: 20 February 2022

To Be a Reviewer

If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Prof. Giustino Varrassi, MD, PhD

Professor Giustino Varrassi, MD, PhD is Professor and former Chairman of the Department of Anesthesia and Pain Medicine, University of L'Aquila, Italy. At the moment, he is president of the Paolo Procacci Foundation, Roma, Italy. His scientific interest is mainly in Pain Medicine as shown by the many initiatives he has organized in his career: Founding Member (1993) and Past-President of the European Pain Federation (EFIC), where he has served in the Executive Board for 21 years; Past-President of the Italian Association for the Study of Pain, where he has served in the Council for over 30 years. In these positions, he has organized over 40 international and national congresses. Moreover, he has an intense publishing activity on Pain Medicine and other aspects of his medical specialty. More recently, he has joined NEMA Research Group. as Senior Consultant.