Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

The aim of Signa Vitae (SV) is to be an unbiased and permanent forum for clinical anesthesia, intensive care, emergency and pain medicine. It serves professionals dedicated to all these relevant fields, as a tool for easier and more effective experiences and science sharing, with the ultimate goal to improve patients’ outcome. The scope of Signa Vitae is broad. It encompasses all aspects of clinical practice and fundamental research at the basis of anesthesia, intensive care, emergency and pain medicine, both in children and adults. It will better inform and educate the global scientific and medical community on the advancements in the fields at the basis of survival and a better quality of life, as stated in the appealing Latin version of its name: "Signs of life".


Open Access

Initial five and ten-minute regional cerebral oxygen saturation as a predictor of the futility of resuscitation for out-of-hospital cardiac arrest

Jae Ho Jang,Yong Su Lim,Woo Sung Choi,Jea Yeon Choi,Jin Seong Cho,Jae-Hyug Woo,Hyuk Jun Yang

DOI: 10.22514/sv.2022.027

Abstract ( 870 ) PDF (9.62 MB) ( 194 ) Full Text

Open Access

A new simple score to predict mortality of COVID-19 in the emergency department

Marcello Candelli,Giulia Pignataro,Marta Sacco Fernandez,Sara Cicchinelli,Antonio Gullì,Enrico Torelli,Maurizio Gabrielli,Andrea Piccioni,Marcello Covino,Veronica Ojetti,Massimo Antonelli,Antonio Gasbarrini,Francesco Franceschi

DOI: 10.22514/sv.2022.025

Abstract ( 740 ) PDF (4.32 MB) ( 181 ) Full Text

Open Access

Predicting mid-term survival of patients during emergency department triage for resuscitation decision

Jae Yong Yu,Hansol Chang,Weon Jung,Sejin Heo,Gun Tak Lee,Jong Eun Park,Se Uk Lee,Taerim Kim,Sung Yeon Hwang,Hee Yoon,Tae Gun Shin,Min Seob Sim,Ik Joon Jo,Won Chul Cha

DOI: 10.22514/sv.2022.018

Abstract ( 842 ) PDF (2.41 MB) ( 220 ) Full Text

Open Access

Factors related to the success or failure of cardioversion in atrial fibrillation and emergency department revisit according to restoration of sinus rhythm: analysis of the URGFAICS cohort

Irene Cabello,Javier Jacob,Oriol Yuguero,María Arranz,Jorge-Alexis Guzmán,Anna Moreno,Paloma Francés,Julia Santos,Anna Esquerrà,Álvaro Zarauza,Josep-María Mòdol,on behalf of URGFAICS Research Group

DOI: 10.22514/sv.2022.020

Abstract ( 815 ) PDF (1.14 MB) ( 165 ) Full Text

Open Access

One year health-related quality of life after discharge: a prospective cohort study among COVID-19 ICU survivors

Valery Likhvantsev,Giovanni Landoni,Artem Kuzovlev,Sergey Perekhodov,Nikolay Chaus,Maddalena Tucci,Mary Ann Belli,Kristina Kadantseva,Lubov Ermokhina,Mikhail Yadgarov,Levan Berikashvili,Valery Subbotin,Nataly Melnikova,Andrey Grechko

DOI: 10.22514/sv.2022.036

Abstract ( 1066 ) PDF (15.15 MB) ( 245 ) Full Text

Open Access

Effect of different combinations of initial body temperature and target temperature on neurological outcomes in out-of-hospital cardiac arrest patients treated with targeted temperature management

Heejun Kim,Taegyun Kim,Jonghwan Shin,Woon Yong Kwon,Gil Joon Suh,Hwanjun Choi,Ji Han Lee,Yoon Sun Jung,Hui Jai Lee,Kyoung Min You,Seung Min Park,Young Taeck Oh,SNU CARE investigators

DOI: 10.22514/sv.2022.029

Abstract ( 890 ) PDF (1.72 MB) ( 177 ) Full Text

Open Access

Morphometric characteristics of interatrial septum in patients with patent foramen ovale and cryptogenic stroke

Qingyuan Zhang,Yudong Peng,Hong Zhang,Xiaoling Wan,Xiao Liu,Wei Xu

DOI: 10.22514/sv.2023.016

Abstract ( 361 ) PDF (2.21 MB) ( 146 ) Full Text

Open Access Special Issue

Prognostic value of serum phosphate level in elderly post-cardiac arrest patients

Hee Eun Kim,Young Taeck Oh,You Hwan Jo,Jonghwan Shin,Seung Min Park,Dong Keon Lee,Yoon Sun Jung,Dong-Hyun Jang,on behalf of the SNU CARE Investigators

DOI: 10.22514/sv.2022.047

(This article belongs to the Special Issue Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021)

Abstract ( 743 ) PDF (1.24 MB) ( 203 ) Full Text

Published Ahead of Print

Open Access

Should lactate levels be combined with rapid emergency medicine scores (REMS) to predict outcomes of patients with dyspnea


Online publish date: 27 March 2023

DOI: 10.22514/sv.2023.024

Abstract ( 202 ) PDF (2.85 MB) ( 130 ) Full Text

Open Access

Contrast extravasation and hematoma volume as predictors of the need for embolization in patients with pelvic fractures

Min A Lee,Byungchul Yu,Jayun Cho,Myung Jin Jang,Gil Jae Lee,Kang Kook Choi,Yang Bin Jeon,Seung Hwan Lee,Youngeun Park

Online publish date: 08 March 2023

DOI: 10.22514/sv.2023.021

Abstract ( 209 ) PDF (4.16 MB) ( 115 ) Full Text

Open Access

Changes in potassium level and renal function with balanced crystalloid administration in the emergency department

Sungsig Kong,Hyuksool Kwon,Jinhee Lee,Dongbum Suh

Online publish date: 08 March 2023

DOI: 10.22514/sv.2023.022

Abstract ( 222 ) PDF (2.49 MB) ( 132 ) Full Text

Open Access

Improving triage accuracy of hospitalization and discharge decisions in the emergency department

Sung-Joon Park,Sung-Hyuk Choi,Dae-Jin Song,Jong-Hak Park,Ju-Hyun Song,Han-Jin Cho,Sun-Hong Lee,Byung-Chul Ko,Kyu-Hwan Ahn,Gil-Gon Kim,Won-Seok Choi,Kyung-Nam Kim

Online publish date: 22 February 2023

DOI: 10.22514/sv.2023.015

Abstract ( 255 ) PDF (4.04 MB) ( 147 ) Full Text

Open Access

Role of lactate measurement in predicting recurrence of seizure within 24 hours in simple febrile seizure patients

Dongwook Lee,Hyung Jun Moon,Hyun Jung Lee,Dongkil Jeong,Hyun Joon Kim,Hyun Noh,Hye Young Jang,Young Soon Cho

Online publish date: 22 February 2023

DOI: 10.22514/sv.2023.013

Abstract ( 256 ) PDF (839.02 kB) ( 145 ) Full Text

Special Issues

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 May 2023

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 30 November 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Special issue title:

21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care

Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens

Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA

Submission deadline: 27 May 2022

Special issue title:

Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021

Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome

Editor: Prof. Won Young Kim, MD, PhD

Submission deadline: 01 June 2022

Special issue title:

Spinal Cord Injury

Keywords: Spinal cord injury (SCI), Damage mechanisms, Primary and secondary medullary lesions, Neurorehabilitation, Neurorestoration

Editor: Lecturer dr. Constantin Munteanu, PhD,Prof. Dr. Gelu Onose,Associate Prof. Dr. Mariana Rotariu, PhD,Assistant Prof. Dr. Gabriela Dogaru, PhD,Associate Prof. Dr. Elena Valentiana IONESCU, PhD,Assistant Prof. Dr. Cristina Daia, PhD

Submission deadline: 31 March 2022

Special issue title:

Outcome Measures and Assessment Tools in Spinal Cord Injury

Keywords: Spinal Cord Injury, Rehabilitation, Assessment Tools

Editor: Dr. Giovanni Galeoto

Submission deadline: 10 December 2021

Special issue title:

Opioid Free Analgesia: new concept, new trends

Keywords: Analgesia, Pain, Opioids, OFA, Regional block

Editor: Dr. Mohamed Adel Aboelela

Submission deadline: 01 April 2022

Special issue title:

Life-Threatening Clinical Situations in The Cardiac Intensive Care Unit

Keywords: Acute coronary syndrome, Cardiomyopathies, Cardiac arrhythmias, Conduction disorders, Valvular heart disease, Aortic dissection, Acute pulmonary thromboembolism

Editor: Dr. Larisa ANGHEL,Dr. Cristian STĂTESCU,Dr. Radu SASCĂU

Submission deadline: 20 February 2022

To Be a Reviewer

If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Prof. Giustino Varrassi, MD, PhD

Professor Giustino Varrassi, MD, PhD is Professor and former Chairman of the Department of Anesthesia and Pain Medicine, University of L'Aquila, Italy. At the moment, he is president of the Paolo Procacci Foundation, Roma, Italy. His scientific interest is mainly in Pain Medicine as shown by the many initiatives he has organized in his career: Founding Member (1993) and Past-President of the European Pain Federation (EFIC), where he has served in the Executive Board for 21 years; Past-President of the Italian Association for the Study of Pain, where he has served in the Council for over 30 years. In these positions, he has organized over 40 international and national congresses. Moreover, he has an intense publishing activity on Pain Medicine and other aspects of his medical specialty. More recently, he has joined NEMA Research Group. as Senior Consultant.