Signa Vitae
Print ISSN: 1334-5605 | Online ISSN: 1845-206X
Signa Vitae (SV) is a peer-reviewed, open-access journal that aims to be an unbiased and permanent forum for the fields of emergency medicine, intensive care medicine, anesthesia and pain medicine. It focuses on the latest research advances in these fields, including Disease prevention, diagnose, treatment and prognosis, Disease etiology, pathophysiology, and molecular mechanisms, Health care, Medical personnel health, Facilities and equipment, Teaching and training, Organization and management, Information and techniques, Drug application, etc. As a tool for easier and more effective experiences and science sharing, SV aims to provide professionals dedicated to all these relevant fields with cutting-edge techniques and information.
Articles
Acute pain management: the role of multimodal analgesia with a focus on dexketoprofen and tramadol hydrochloride fixed-dose combination in acute low back pain
Acute pain management: the role of multimodal analgesia with a focus on dexketoprofen and tramadol hydrochloride fixed-dose combination in acute low back pain
DOI: 10.22514/sv.2025.078
QTc changes in elderly patients: a comparison of spinal and general anesthesia
QTc changes in elderly patients: a comparison of spinal and general anesthesia
DOI: 10.22514/sv.2025.079
Effects of bupivacaine wound infiltration and transversus abdominus plane block on healing and postoperative adhesion of colonic anastomosis in rats
Effects of bupivacaine wound infiltration and transversus abdominus plane block on healing and postoperative adhesion of colonic anastomosis in rats
DOI: 10.22514/sv.2025.029
Epidemiologic characteristics of intentional poisoning in Korea—a retrospective analysis of the EDIIS database (2011–2020)
Epidemiologic characteristics of intentional poisoning in Korea—a retrospective analysis of the EDIIS database (2011–2020)
DOI: 10.22514/sv.2025.082
Comparative study of dexmedetomidine and esketamine in elderly patients undergoing percutaneous vertebroplasty
Comparative study of dexmedetomidine and esketamine in elderly patients undergoing percutaneous vertebroplasty
DOI: 10.22514/sv.2025.083
Variations in oxygen reserve index in different fresh gas flow rates
Variations in oxygen reserve index in different fresh gas flow rates
DOI: 10.22514/sv.2025.084
Evaluation of ropivacaine in external oblique intercostal block for analgesia in major upper abdominal surgery: a randomized controlled clinical trial
Evaluation of ropivacaine in external oblique intercostal block for analgesia in major upper abdominal surgery: a randomized controlled clinical trial
DOI: 10.22514/sv.2025.075
Evaluation of the prognostic value of systemic inflammation indexes in patients diagnosed with acute coronary syndrome in the emergency department
Evaluation of the prognostic value of systemic inflammation indexes in patients diagnosed with acute coronary syndrome in the emergency department
DOI: 10.22514/sv.2025.085
TRIM21 alleviates acute pancreatitis cell injury and promotes efferocytosis by targeting CD47
TRIM21 alleviates acute pancreatitis cell injury and promotes efferocytosis by targeting CD47
DOI: 10.22514/sv.2025.086
Etiology of pediatric forensic cases: comparison of emergency department admissions in childhood and adolescence
Etiology of pediatric forensic cases: comparison of emergency department admissions in childhood and adolescence
DOI: 10.22514/sv.2025.087
Exploring the development and trends of cardiopulmonary resuscitation training: a bibliometric and visual analysis from 1995 to 2024
Exploring the development and trends of cardiopulmonary resuscitation training: a bibliometric and visual analysis from 1995 to 2024
DOI: 10.22514/sv.2025.088
KLF4 promotes sevoflurane-induced neurotoxicity by suppressing FOXO1 expression in neonatal rats
KLF4 promotes sevoflurane-induced neurotoxicity by suppressing FOXO1 expression in neonatal rats
DOI: 10.22514/sv.2025.089
Type II citrullinemia presenting with psychiatric disorder in the emergency department: a case report
Type II citrullinemia presenting with psychiatric disorder in the emergency department: a case report
DOI: 10.22514/sv.2025.090
Published Ahead of Print
The arc of a life in critical care research—in memory of Professor Rinaldo Bellomo (1956–2025)
The arc of a life in critical care research—in memory of Professor Rinaldo Bellomo (1956–2025)
Online publish date: 17 June 2025
DOI: 10.22514/sv.2025.091
Comparative analysis of standard versus prolonged prone positioning in C-ARDS: outcomes on oxygenation and respiratory mechanics
Comparative analysis of standard versus prolonged prone positioning in C-ARDS: outcomes on oxygenation and respiratory mechanics
Online publish date: 30 May 2025
DOI: 10.22514/sv.2025.077
Acute normovolemic hemodilution in cardiac surgery and the power of global collaboration in advancing research
Acute normovolemic hemodilution in cardiac surgery and the power of global collaboration in advancing research
Online publish date: 26 May 2025
DOI: 10.22514/sv.2025.076
Special Issues
Advances in Emergency Cardiac Care
Keywords: Ischemic Heart Disease; Heart Failure; Arrhythmia; Defibrillation; PCI; Telemedicine; Resuscitation
Editor: Prof. Dr. Ozgur Karcioglu, MD, FEMAT,Assoc. Prof. Dr. Canan Akman, MD
Submission deadline: 01 March 2026
Acute Trauma: Immediate Interventions, Long-Term Impacts, Advancements, and Medico-legal Evaluation
Keywords: EMS; Trauma Management; Healthcare System Preparedness; Medico-Legal Evaluation
Editor: Prof. Dr. Giuseppe Basile, MD,Dr. Luca Bianco Prevot, MD,Dr. Vittorio Bolcato, MD
Submission deadline: 31 January 2026
Advances in the Diagnosis and Management of Sepsis and Septic Shock
Keywords: Diagnosis; Management; Sepsis; Septic Shock; Lactate Hypotension; Vasopressors
Editor: Prof. Dr. Ozgur Karcioglu, MD,Assoc. Prof. Dr. Feride Sinem AKGUN, MD,Assist. Prof. Dr. Betul AKBUGA OZEL, MD
Submission deadline: 01 May 2026
Optimization of Cardiovascular Dynamics in Critical Care Medicine and Anesthesiology
Keywords: Critical Care Medicine; Anesthesiology; Cardiovascular Dynamics; Hemodynamics
Editor: Prof. Dr. Athanasios Chalkias, MD, MSc, PhD, FESC, FAcadTM, FCP, FESAIC,Dr. Paraskevi Tselioti, MD, PhD
Submission deadline: 31 December 2025
Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research
Keywords: Emergency Medical Services; Interdisciplinary Research in EMS; Pre-hospital Care Technologies; Crisis Management in Healthcare; Psychological Aspects of EMS; Public Health and Emergency Services
Editor: Prof. Dr. Krzysztof Goniewicz, PhD,Prof. Dr. Ahmed M. Al-Wathinani, PhD
Submission deadline: 28 February 2025
Advances in Obstetric Anaesthesia
Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia
Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA
Submission deadline: 31 December 2023
Cardiothoracic anaesthesia and intensive care: current challenges and novelties
Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges
Editor: Dr. Marko Zdravkovic, MD, PhD
Submission deadline: 30 November 2022
Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022
Keywords: Emergency medicine
Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD
Submission deadline: 31 December 2022
Medical Simulation - success in education, future of science
Keywords: medical simulation, emergency medicine, medical education
Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD
Submission deadline: 31 December 2022
21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care
Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens
Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA
Submission deadline: 27 May 2022
To Be a Reviewer
If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.
Review for SVJoin Editorial Board
You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.
Join Editorial BoardEditor-in-Chief
Prof. Giovanni Landoni, MD
Prof Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals.