Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

The aim of Signa Vitae (SV) is to be an unbiased and permanent forum for clinical anesthesia, intensive care, emergency and pain medicine. It serves professionals dedicated to all these relevant fields, as a tool for easier and more effective experiences and science sharing, with the ultimate goal to improve patients’ outcome. The scope of Signa Vitae is broad. It encompasses all aspects of clinical practice and fundamental research at the basis of anesthesia, intensive care, emergency and pain medicine, both in children and adults. It will better inform and educate the global scientific and medical community on the advancements in the fields at the basis of survival and a better quality of life, as stated in the appealing Latin version of its name: "Signs of life".


Open Access Special Issue

High flow nasal cannula therapy in children: working principles and treatment failure predictors

Eleni Volakli,Menelaos Svirkos,Asimina Violaki,Elpis Chochliourou,Serafeia Kalamitsou,Vasiliki Avramidou,Maria Katsafiloudi,Despoina Iordanidou,Nikolaos Karantaglis,Maria Sdougka

DOI: 10.22514/sv.2022.039

(This article belongs to the Special Issue Pediatric Critical Care)

Abstract ( 1352 ) PDF (564.23 kB) ( 280 ) Full Text

Open Access Special Issue

Artificial intelligence for the triage of COVID-19 patients at the emergency department: a systematic review

Pablo Redruello-Guerrero,Carmen Jiménez-Gutiérrez,Antonio Jesús Láinez Ramos-Bossini,Paula María Jiménez-Gutiérrez,Mario Rivera-Izquierdo,José Manuel Benítez Sánchez

DOI: 10.22514/sv.2022.069

(This article belongs to the Special Issue COVID-19 in the Emergency Department: Epidemiology and changes throughout the pandemic)

Abstract ( 501 ) PDF (846.48 kB) ( 167 ) Full Text

Open Access Special Issue

Impact of COVID-19 pandemic waves on pediatric emergency department patients presenting with asthma attacks in Taiwan

Hsin-Kuan Wu,En-Shuo Chang,Chien-Wei Cheng,Wei-Che Chien,Hsin-Hui Chou

DOI: 10.22514/sv.2022.045

(This article belongs to the Special Issue COVID-19 in the Emergency Department: Epidemiology and changes throughout the pandemic)

Abstract ( 840 ) PDF (2.56 MB) ( 170 ) Full Text

Open Access Special Issue

Hydroxyethyl starch impairs renal water reabsorption in patients with cardiac shock

Zhi-Jie Yue,Zhan Shi,Zhuo Xie,Chun-Ming Li,Zhi-Yuan Guo,Meng Guo,Zhen-Guo Wang,Da-Jie Hao

DOI: 10.22514/sv.2021.136

(This article belongs to the Special Issue Biomarkers and Action Strategies in Early and Subclinical Acute Kidney Injury)

Abstract ( 1100 ) PDF (270.46 kB) ( 179 ) Full Text

Open Access Special Issue

Sex differences in hospitalized COVID-19 patients

Rosaria Sofia,Martina Baiardo Redaelli,Olivia Belloni,Perla Cicero,Giovanni Landoni,Alberto Zangrillo

DOI: 10.22514/sv.2022.011

(This article belongs to the Special Issue COVID-19 in the Emergency Department: Epidemiology and changes throughout the pandemic)

Abstract ( 1049 ) PDF (2.38 MB) ( 160 ) Full Text

Open Access

COL3A1 induces ischemic heart failure by activating AGE/RAGE pathway

Xiao Chen,Jiawei Zhang,Tong Li,Zhaosheng Ding,Cao Zou

DOI: 10.22514/sv.2022.072

Abstract ( 346 ) PDF (6.77 MB) ( 161 ) Full Text

Open Access

Quality of life in osteoporotic patients with low-grade degenerative spondylolisthesis

Magdalena Rodica Traistaru,Diana Kamal,Constantin Kamal,Dragos Ovidiu Alexandru,Simona-Daniela Neamtu,Ana Maria Bumbea

DOI: 10.22514/sv.2022.022

Abstract ( 724 ) PDF (4.81 MB) ( 159 ) Full Text

Open Access

Endotracheal intubation during chest compressions in the pediatric simulation setting: a systematic review and meta-analysis

Filippo Sanfilippo,Simone Messina,Federica Merola,Stefano Tigano,Alberto Morgana,Arnaldo Dimagli,Luigi La Via,Marinella Astuto

DOI: 10.22514/sv.2022.034

Abstract ( 684 ) PDF (2.41 MB) ( 165 ) Full Text

Open Access Special Issue

Cardiac tamponade as an unusual initial presentation of squamous cell carcinoma of the esophagus

Nitchakarn Hongsuphan,Saowaluck Faikongngeon,Wachira Wongtanasarasin

DOI: 10.22514/sv.2021.120

(This article belongs to the Special Issue Efficacy of Medication Administered During Adult Cardiac Arrest)

Abstract ( 1289 ) PDF (1.27 MB) ( 216 ) Full Text

Published Ahead of Print

Open Access

Will the road traffic act reduce electric scooter injuries?: an observational study in Republic of Korea

Yong Wook Jeong,Young Ho Seo,Soo Kang

Online publish date: 18 November 2022

DOI: 10.22514/sv.2022.079

Abstract ( 232 ) PDF (1.38 MB) ( 136 ) Full Text

Open Access

Predictors of non-invasive ventilation failure in adult patients with cardiac dysfunction presenting with community-acquired pneumonia: an Egyptian multicenter prospective study

Mohamed Laimoud,Muhammed Abdel-Moaty,Mohamed Elshobary,Thanaa Mohamed,Walid Ahmed

Online publish date: 18 November 2022

DOI: 10.22514/sv.2022.078

Abstract ( 258 ) PDF (4.63 MB) ( 141 ) Full Text

Open Access

Ventilation in critically ill obese patients—Why it should be done differently?

Cristian Cobilinschi,Ana-Maria Cotae,Raluca Ungureanu,Radu Țincu,Ioana Marina Grințescu,Liliana Mirea

Online publish date: 10 November 2022

DOI: 10.22514/sv.2022.076

Abstract ( 251 ) PDF (189.23 kB) ( 138 ) Full Text

Special Issues

Special issue title:

Improving Survival from Cardiac Arrest: A Review of Current Practice and Challenges

Keywords: Cardiac Arrest; CPR; Resuscitation; OHCA; IHCA

Editor: Dr. Wachira Wongtanasarasin

Submission deadline: 30 September 2023

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 May 2023

Special issue title:

Nutrition in Critically Ill Patients

Keywords: Critically ill patient; Enteral nutrition; Parenteral nutrition; Micronutrients; Macronutrients

Editor: Prof. Dr. Mahmoud M. A. Abulmeaty, MD, FACN

Submission deadline: 31 March 2023

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 30 November 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Special issue title:

21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care

Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens

Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA

Submission deadline: 27 May 2022

Special issue title:

Selected papers from Korean Association of Cardiopulmonary Resuscitation in 2021

Keywords: Cardiac arrest, Resuscitation, cardiopulmonary resuscitation, guidelines, outcome

Editor: Prof. Won Young Kim, MD, PhD

Submission deadline: 01 June 2022

Special issue title:

Spinal Cord Injury

Keywords: Spinal cord injury (SCI), Damage mechanisms, Primary and secondary medullary lesions, Neurorehabilitation, Neurorestoration

Editor: Lecturer dr. Constantin Munteanu, PhD,Prof. Dr. Gelu Onose,Associate Prof. Dr. Mariana Rotariu, PhD,Assistant Prof. Dr. Gabriela Dogaru, PhD,Associate Prof. Dr. Elena Valentiana IONESCU, PhD,Assistant Prof. Dr. Cristina Daia, PhD

Submission deadline: 31 March 2022

Special issue title:

Outcome Measures and Assessment Tools in Spinal Cord Injury

Keywords: Spinal Cord Injury, Rehabilitation, Assessment Tools

Editor: Dr. Giovanni Galeoto

Submission deadline: 10 December 2021

To Be a Reviewer

If you would like to volunteer to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (both editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Prof. Giustino Varrassi, MD, PhD

Professor Giustino Varrassi, MD, PhD is Professor and former Chairman of the Department of Anesthesia and Pain Medicine, University of L'Aquila, Italy. At the moment, he is president of the Paolo Procacci Foundation, Roma, Italy. His scientific interest is mainly in Pain Medicine as shown by the many initiatives he has organized in his career: Founding Member (1993) and Past-President of the European Pain Federation (EFIC), where he has served in the Executive Board for 21 years; Past-President of the Italian Association for the Study of Pain, where he has served in the Council for over 30 years. In these positions, he has organized over 40 international and national congresses. Moreover, he has an intense publishing activity on Pain Medicine and other aspects of his medical specialty. More recently, he has joined NEMA Research Group. as Senior Consultant.