Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Cardiac surgery and sepsis in postoperative period – our experience
1Zagreb University Clinical Hospital Centre – KBC Zagreb, Clinic of Anaesthesiology, Reanimatology and Intensive Care, Department of Anaesthesiology and Intensive Care for Cardiac Surgery Patients, Zagreb, Croatia
*Corresponding Author(s): VIŠNJA IVANČAN E-mail: vivancan@gmail.com
The occurrence of sepsis after cardiac surgery is a rare event; however, its oc-currence showed catastrophic clinical outcomes. The high morbidity and mor-tality revealed the need to improve treat-ment, aiming at patients’ better clinical outcome.
Patients that develop sepsis, regardless of the infectious focus and the subjacent dis-ease, present high morbidity and mortali-ty, which vary from 17% to 65%. The main predictors of infections in the postopera-tive period are: body mass index ≥40kg/m², haemodialysis in the preoperative period, pre-op cardiogenic shock, age ≥80 years, pre-op treatment with immunosup-pressive agents, diabetes mellitus, ECC time ≥200 minutes, mechanical circula-tory support, three or more revascular-ized vessels.
From January 2015 to December 2015, we studied 675 adult patients who underwent cardiac surgery. Prophylactic antibiotic therapy was prescribed and given accord-ing to our protocol, from the induction of anaesthesia to the first postoperative day. Sepsis in the postoperative period was defined as evidence on infection associ-ated with two or more criteria of systemic inflammatory response syndrome: body temperature >38°C or <36°C, leukocytes >12,000 cells/mm³, positive blood cul-tures, respiratory rate >20/min, heart rate>100/min.
sepsis, postoperative period, cardiac surgery
VIŠNJA IVANČAN,MARIO PAVLEK,ŽELJKO ČOLAK,RAJKA GABELICA,MIRABEL MAŽAR,SANJA KONOSIĆ,GORDANA RAJSMAN,SANDRA UZUN. Cardiac surgery and sepsis in postoperative period – our experience. Signa Vitae. 2016. 11(S2);44-46.
1. Silva E, Fernandes Jr CJ, Akamine N, Sogayar AMCB, Knobel E. Sepse e choque séptico. In: Knobel E. Condutas no paciente grave. 3ª ed. São Paulo: Editora Atheneu; 2006. p. 61-78.
2. Fowler VG, O`Brain SJ, Muhlbaier LH, Corey GH, Ferguson BT, Peterson ER. Clinical predictors of major infections after cardiac surgery. Circulation. 2005;(1):112: I358-I365.
3. Slaughter MS, Olson MM, Lee JT Jr, Ward HB. A fifteen years wound surveillance study after coronary artery bypass. Ann Thorac Surg. 1993;56(5):1063-1068.
4. Toumpoulis IK, Anagnostopoulus CE, Toumpuolis SK, De Rose Jr JJ, Swistel DG. Risk factors for sepsis and endocarditis and long-term survival following coronary artery bypass grafting. World J Surg. 2005;29(5):621-627.
5. Michalopoulos A, Stavridis G, Geroulanos S. Severe sepsis in cardiac surgical patients. Eur J Surg. 1998;164: 217-222.
6. Dellinger RF, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med. 2008;36(1):296-327.
Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.
Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.
Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.
Index Copernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.
Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.
Scopus: CiteScore 1.3 (2023) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.
Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.
Top