Article Data

  • Views 1562
  • Dowloads 122

Original Research

Open Access

Optic neuritis caused by aspergilloma within Onodi cell pyomucocele in a 62-year-old woman


1Department of Emergency Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea

2 Department of Radiology, Aerospace Medical Center, Republic of Korea Air Force, Cheongwon-gun, Republic of Korea

DOI: 10.22514/SV132.112017.20 Vol.13,Issue 2,November 2017 pp.120-122

Published: 06 November 2017

*Corresponding Author(s): SEONG JONG YUN E-mail:


Onodi cells are anatomical variants of the posterior ethmoidal cells, which are greatly pneumatized laterally, and to some degree superiorly, to the sphenoid sinuses. Th e clinical importance of the Onodi cell is that it contains the optic canal and lies in close proximity to the optic nerve. Al-though the incidence of Onodi cell pa-thologies such as mucocele is extremely low, they may cause ophthalmological complications due to the close anatomical proximity between the Onodi cell and the optic nerve. Optic neuritis caused by as-pergillosis of the Onodi cell, presenting in the Emergency Department as an aspergil-loma within a pyomucocele, has not been reported previously. Here, we describe the fi rst such case; the aspergilloma within the pyomucocele was completely removed via surgical endoscopy.


optic neuritis, onodi cell pyomu-cocele, aspergilloma, CT, MRI

Cite and Share

SUN HWA LEE,SEONG JONG YUN. Optic neuritis caused by aspergilloma within Onodi cell pyomucocele in a 62-year-old woman. Signa Vitae. 2017. 13(2);120-122.


1. Trobe JD, Sieving PC, Guire KE, Fendrick AM. The impact of the optic neuritis treatment trial on the practices of ophthalmologists and neurologists. Ophthalmology 1999;106:2047-53.

2. Driben JS, Bolger WE, Robles HA, Cable B, Zinreich SJ. The reliability of computerized tomographic detection of the Onodi (sphe-noethmoid) cell. American J Rhinol 1998;12:105-11.

3. Tomovic S, Esmaeili A, Chan NJ, Choudhry OJ, Shukla PA, Liu JK, et al. High‐resolution computed tomography analysis of the prevalence of onodi cells. Laryngoscope 2012;122:1470-3.

4. Onodi A. III. Die Sehstörungen und Erblindung nasalen Ursprunges, bedingt durch Erkrankungen der hinteren Nebenhöhlen. Ophthalmologica 1904;12:23-46.

5. Nickerson JP, Lane AP, Subramanian PS, Izbudak I. Onodi cell mucocele causing acute vision loss. Clin Neuroradiol 2011;21:245-8.

6. Cheon YI, Hong SL, Roh HJ, Cho KS. Fungal ball within Onodi cell mucocele causing visual loss. J Craniofac Surg 2014;25:512-4.

7. Dunya IM, Frangieh GT, Heilman CB, Miranda MR, Rand LI, Hedges TR. Anterior clinoid mucocele masquerading as retrobulbar neuritis. Ophthal Plast Reconstr Surg 1996;12:171-3.

8. Johnson LN, Hepler RS, Yee RD, Batzdorf U. Sphenoid sinus mucocele (anterior clinoid variant) mimicking diabetic ophthalmople-gia and retrobulbar neuritis. Am J Ophthalmol 1986;102:111-5.

9. Toh ST, Lee JC. Onodi cell mucocele: rare cause of optic compressive neuropathy. Arch Otolaryngol Head Neck Surg 2007;133:1153-6.

10. Hickman SJ, Miszkiel KA, Plant GT, Miller DH. The optic nerve sheath on MRI in acute optic neuritis. Neuroradiology 2005;47:51-5.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.

Index Copernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.

Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.

Scopus: CiteScore 1.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.

Submission Turnaround Time