Article Data

  • Views 4162
  • Dowloads 160

Case Report

Open Access

Chryseobacterium gleum infection in patient with extreme malnutrition and hepatic lesion – case report

  • DIJANA VARDA BRKIĆ1
  • OZRENKA ZLOPAŠA2
  • BRANKA BEDENIĆ1,3
  • VANDA PLEČKO1,3

1Department of Clinical and Molecular Microbiology, Clinical Hospital Centre Zagreb, Kišpatićeva 12, Zagreb, Croatia

2Division of Intensive Care Medicine, Department of Internal Medicine, Clinical Hospital Centre Zagreb, Kišpatićeva 12, Zagreb, Croatia

3School of Medicine, University of Zagreb, Zagreb, Croatia

DOI: 10.22514/SV101.062015.13 Vol.10,Issue S1,June 2015 pp.50-52

Published: 22 June 2015

*Corresponding Author(s): DIJANA VARDA BRKIĆ E-mail: dijanavb098@gmail.com

Abstract

Chrysobacterium gleum is a nonmotile, oxidase positive, non-fermentative un-sporulate Gram-negative bacillus, bacteria belonging to the genus Chrysobacterium. Infections caused by Chrysobacterium spp are usually health care associated and the most frequent in immunocompromised patients and neonates.

In this report we present a case of a 35-year-old female patient admitted to the hospital for extreme malnutrition and a hepatic le-sion. Chrysobacterium gleum was isolated from tracheal aspirate and blood culture. The strain was identified with Microflex MALDI Biotyper (Bruker Daltonik, Fre-mont, CA). The patient was successfully treated with piperacillin/tazobactam. Em-pirical therapy is difficult due to intrinsic resistance to most antimicrobials which are usually effective against Gram-negative bacteria.

Keywords

Chrysobacterium gleum, MAL-DI-TOF, susceptibility pattern, piperacillin/tazobactam, health care associated infec-tions

Cite and Share

DIJANA VARDA BRKIĆ,OZRENKA ZLOPAŠA,BRANKA BEDENIĆ,VANDA PLEČKO. Chryseobacterium gleum infection in patient with extreme malnutrition and hepatic lesion – case report. Signa Vitae. 2015. 10(S1);50-52.

References

1. 8th Mandell GL, Douglas, and Bennett JE. Principles and Practice of Infectious Diseases, Edition. New York Elsevier; 2010: 3022-3023.

2. Lo HH, Chang SM. Identification, characterization, and biofilm formation of clinical Chryseobacterium gleum isolates. Diagn Microbiol Infect Dis. 2014; 79 (3): 298-302

3. Lee K, Lim YS, Yong D, et al.. Evaluation of the Hodge test and the imipenem-EDTA-double-disk synergy test for differentiating metallo-β-lactamase-producing isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol 2003; 41:4623- 4629.

4. Clinical and Laboratory Standards Institute 2013. Performance Standards for Antimicrobial Susceptibility Testing; 23rd Informa-tional Supplement, M100-S23.Wayne, PA: CLSI

5. Elwell LP, Falkow S. The characterizatio of R plasmids and the detection of  plasmid-specified genes. In: Lorian V, ed. Antibiotics in Laboratory Medicine. 2nd edn. Baltimore MD: Williams and Wilkins, 1986: 683-721.

6. Poirel L, Walsh TR, Cuveiller V, et al.Multiplex PCR for detection of acquired carbapenemases genes. Diagn Microbiol Infect Dis 2011; 0:119-125.

7. Virok DP, Abrok M, Szel B, et al. Chryseobacterium gleum – a novel bacterium species detected in neonatal respiratory tract infec-tions. J Matern Fetal Neonatal Med. 2014; 14.

8. European Committee on Antimicrobial Susceptibility Testing (EUCAST). Website with MIC distribution. (http://mic.eucasr.org)/available from March 2010).

9. Kirby JT, Sader HS, Walsh TR, et al. Antimicrobial Susceptibility and Epidemiology of a Worldwide Collection of Chryseobacte-rium spp.: Report from the SENTRY Antimicrobial Surveillance Program (1997-2001).

10. Bridet L, Martin JJ, Nuno JL. Acute liver damage and anorexia nervosa: a case report. Turk J Gastroenterol. 2014; 25(2):205-8.

Submission Turnaround Time

Top