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NTpro-BNP – diagnostic significance and recommended clinical applications


1Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Zagreb, Croatia

DOI: 10.22514/SV101.062015.28 Vol.10,Issue S1,June 2015 pp.89-91

Published: 22 June 2015

*Corresponding Author(s): DUNJA ROGIĆ E-mail:


Brain natriuretic peptides are elevated in circulation in proportion to a decrease in myocardial function. They have been uni-formly shown to have excellent negative predictive value in differential diagnosis of dyspnoea. They can also be used in diag-nosing heart failure and have been recently shown as possible prognostic markers in acute coronary syndrome and pulmonary embolism. It is important to note that brain natriuretic peptide values rise with age and are inversely proportional to body mass index and glomerular filtration rate.


Brain natriuretic peptide N-terminal brain natriuretic peptide, heart failure

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DUNJA ROGIĆ. NTpro-BNP – diagnostic significance and recommended clinical applications. Signa Vitae. 2015. 10(S1);89-91.


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