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Toxicological screening - Experience from University Hospital Centre Zagreb Emergency Medical Service


1Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Croatia

DOI: 10.22514/SV101.062015.29 Vol.10,Issue S1,June 2015 pp.92-96

Published: 22 June 2015

*Corresponding Author(s): ANDRIJANA ŠČAVNIČAR E-mail:


The aim of toxicological screening is to de-tect drugs of abuse and other drugs, or to demonstrate that they have not been taken. It is performed with a variety of tests capa-ble to detect certain substance or a group of substances. Urine is a sample of choice for toxicological screening because of less invasive sampling and the prolonged de-tection time of substances in urine. The Department of Laboratory Diagnostics at the University Hospital Centre Zagreb used to perform screening with thin-layer chromatography and confirm results with GC-MS analysis. Since September 2014, the Department has been using GC-MS for toxicological screening 24 hours a day. Compared to the previous period, the ex-perience acquired so far has shown that there are a significantly lower number of samples with unknown substances that cannot be confirmed with certainty.


gas chromatography, mass spec-trometry, toxicological screening

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ANDRIJANA ŠČAVNIČAR,PAULA GRANIĆ,MILA LOVRIĆ,DUNJA ROGIĆ. Toxicological screening - Experience from University Hospital Centre Zagreb Emergency Medical Service. Signa Vitae. 2015. 10(S1);92-96.


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