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Incidence of hyponatraemia in the emergency unit
1Merkur University Hospital, Department of Internal Medicine, University of Zagreb, School of Medicine, Zagreb, Croatia
2Zagreb University School of Medicine, Zagreb, Croatia
3General Hospital Vinkovci, Department of Internal Medicine, Vinkovci, Croatia
*Corresponding Author(s): INGRID PRKAČIN E-mail: ingrid.prkacin@gmail.com
Hyponatraemia is an electrolyte disorder, defined as a serum sodium concentration (Na) <136 mmol/L. It occurs in up to 30% of hospitalised patients. The purpose of this study was to evaluate the frequency of hyponatraemia among all patients during a one month period in the emergency unit. During the one month period in 2014, 570 patients were included in this study. The study was approved by local ethics com-mittees and patients provided written in-formed consent.
Out of the 570 patients, 41 (7%) had hy-ponatraemia. The median age was 67 (65.02±14.09) years and the majority of the patients were men (M:F = 23:18; 56.1:43.9%). Mild hyponatraemia (serum Na 130-135 mmol/L) was found in 71% (29/41), moderate (serum Na 125-129 mmol/L) in 17% (7/41), severe (serum Na 120-124 mmol/L) in 5% (2/41), and ex-tremely severe (serum Na< 120 mmol/L) in 7% (3/41) of patients. The treatment options included the restriction of fluid intake by administering hypertonic saline and loop diuretics.
We should be alert to acute hyponatraemia, especially in elderly patients with neuro-logical manifestations and poor progno-sis. The presented data are an important contribution to the better understanding of the epidemiology of hyponatraemia in Croatia.
hyponatraemia, emergency unit
INGRID PRKAČIN,VALENTINA ĆORIĆ MARTINOVIĆ,VESNA ĐERMANOVIĆ DOBROTA,ANA LEGOVIĆ,BORNA VRHOVEC,GORDANA CAVRIĆ,PETRA DRAŽIĆ. Incidence of hyponatraemia in the emergency unit. Signa Vitae. 2015. 10(S1);29-31.
1. Upadhyay A, Jaber BL, Madias NE. Incidence and prevalence of hyponatremia. Am J Med 2006; 119: S30–S35.
2. Hoorn EJ, Zietse RA. Hyponatremia and mortality: how innocent is the bystander? Clin J Am Soc Nephrol 2011; 6: 951–953.
3. Thompson C, Berl T, Tejedor A et al. Differential diagnosis of hyponatraemia. Best Pract Res Clin Endocrinol Metab 2012; 26: S7–S15.
4. Kim DK, Joo KW. Hyponatremia in patients with neurologic disorders. Electrolyte Blood Press 2009; 7:51-57.
5. Schrier RW, Sharma S, Shchekochikhin D. Hyponatremia: more than just a marker of disease severity? Nat Rev Nephrol 2013; 9:
37- 50.
6. Fillippatos TD, Elisaf MS. Hyponatremia in patients with heart failure. World J Cardiol 2013; 5: 317-328.
7. Liamis G, Milionis H, Elisaf M. A review of drug-induced hyponatremia. Am J Kidney Dis 2008; 52: 144–153.
8. Onitilo AA, Kio E, Doi SA. Tumor-related hyponatremia. Clin Med Res 2007; 5: 228–237.
9. Sharabi Y, Illan R, Kamari Y et al. Diuretic induced hyponatraemia in elderly hypertensive women. J Hum Hypertens 2002; 16:
631- 635.
10. Soupart A, Coffernils M, Couturier B,Gankam-Kengne F, Decaux G. Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH. Clin J Am SocNephrol 2012;7: 742-747.
11. Sterns RH. Disorders of Plasma Sodium — Causes, Consequences, and Correction. N Engl J Med 2015; 372: 55-65. DOI: 10.1056/NEJMra1404489.
12. Spasovski G, Vanholder R, Allolio B et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Nephrol Dial Transplant 2014; 29: Suppl 2: i1-i39.
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