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Original Research

Open Access

Renal denervation in patients with resistant hypertension - single centre report


1Department of Internal Medicine, University Hospital Merkur, Zagreb, Croatia

2Zagreb University School of Medicine, Zagreb, Croatia

3Department of Radiology, Merkur Clinical Hospital, Zagreb, Croatia

DOI: 10.22514/SV101.062015.8 Vol.10,Issue S1,June 2015 pp.32-34

Published: 22 June 2015

*Corresponding Author(s): INGRID PRKAČIN E-mail:


Among patients with resistant hyperten-sion, it is very important to select patients most likely to benefit from renal sympa-thetic denervation, because they represent a very mixed group of diagnoses. 

Prior to diagnosing a patient as having resistant hypertension, it is important to document adherence and exclude white-coat hypertension, inaccurate measure-ments of blood pressure and secondary causes of hypertension. 

Renal sympathetic denervation has been demonstrated as an antihypertensive treat-ment in resistant hypertension patients with additional positive effects on glucose metabolism and insulin sensitivity in type 2 diabetes. 

We report a single centre report of renal sympathetic denervation effects in a small cohort of patients with resistant hyperten-sion and stage 2-3 chronic kidney disease. Blood pressure reduction after renal sym-pathetic denervation was sustained at con-secutive follow-up visits one, three and six months when compared to the baseline: office systolic blood pressure was signifi-cantly lower (144 ± 13, 140 ± 17, 141 ± 15 mmHg, p<0.001). 

Randomized clinical trials are required to assess the impact of the reported changes. 


resistant hypertension, stepwise screening protocol, renal denervation

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INGRID PRKAČIN,GORDANA CAVRIĆ,BORNA VRHOVEC,ANA LEGOVIĆ,PETRA DRAŽIĆ,VESNA ĐERMANOVIĆ DOBROTA,IVA BORAS,VINKO VIDJAK. Renal denervation in patients with resistant hypertension - single centre report. Signa Vitae. 2015. 10(S1);32-34.


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