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Open AccessIndications for blood transfusions in critical illness
Indications for blood transfusions in critical illness
- ROBERT BARONICA1
- DINKO TONKOVIĆ1
- BOJANA ĐUROVIĆ MRŽLJAK1
- LOREDANA ĐURIĆ1
- TIHOMIR KUŠIĆ1
- KAROLINA REŽEK1
1University Department of Anaesthesiology, Reanimatology and Intensive Care, University Hospital Centre Zagreb
*Corresponding Author(s): ROBERT BARONICA E-mail: rbaronica@gmail.com
Abstract
Transfusion of blood products should improve tissue oxygenation and reduce negative consequences of anaemia. At the same time, adverse effects of transfusion, such as infections, immunologic reactions and mistransfusion, could be deleterious. Most transfusion guidelines suggest look-ing at the combination of haemoglobin or haematocrit levels in addition to clinical signs in the decision making process for a blood transfusion. The problem with such indications is that the clinical evaluation may be misleading in severely ill patients and haemoglobin levels that impair oxy-gen delivery cannot be determined easily. Many studies attempted to establish more convenient parameters, such as oxygen saturation from mixed and central ve-nous blood, tissue oxygen extraction and other methods. Although the results from these studies are conflicting, it appears that global oxygenation parameters are a good indicator for a blood transfusion in some categories of critically ill patients.
Keywords
haemoglobin concentration, global oxygenation parameters, transfusion, critical illness
Cite and Share
ROBERT BARONICA,DINKO TONKOVIĆ,BOJANA ĐUROVIĆ MRŽLJAK,LOREDANA ĐURIĆ,TIHOMIR KUŠIĆ,KAROLINA REŽEK. Indications for blood transfusions in critical illness . Signa Vitae. 2015. 10(S1);35-40.
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