Using age, arterial lactate level and sequential organ failure assessment score in risk stratification of sepsis syndromes
1Critical Care Medicine Department – Alexandria University, Egypt
2 Clinical Pharmacy and Pharmacy Practice Department – Damanhour University, Egypt
DOI: 10.22514/SV151.042019.6 Vol.15,Issue 1,April 2019 pp.46-50
Published: 23 April 2019
Introduction: In low income countries, ICU places are limited and not all sepsis patients will benefit from ICU admission. Stratification is an important step to iden-tify patients who require ICU treatment from patients who can be treated on gen-eral ward setting. Improper stratification results in increased length of stay, costs, morbidity and mortality. Objective: The aim of this study was to stratify the risk of mortality in patients with sepsis syn-drome using age, arterial lactate level and SOFA score. Methods: In this prospective observational study, 250 patients with sepsis were enrolled and followed up un-til discharge. They were categorized into 2 groups according to 7-days mortality. Re-sults: SOFA score (≥5) was the only good tool (AUC=0.722) while age (≥65 years) (AUC=0.650) and arterial lactate (≥3.25 mmol/L) (0.690) were fair tools to predict 7-days mortality. A new score “ALSOFA score” (≥10) was an excellent tool for pre-diction (AUC =0.912, 95%CI: 0.851 to 0.940, p<0.0001). It showed an excellent sensitivity (90.9%) and specificity (85.1%). Conclusion: In critically ill patients with sepsis syndromes, age, arterial lactate and SOFA score are fair tools of stratification. No single marker/score can be used alone to stratify such patients.
Emergency, Critical, Sepsis, SOFA, Arterial Lactate, Stratification
AMR ELMORSI,AMR DAHROUG,ENAL FAHMY,ISLAM AHMED. Using age, arterial lactate level and sequential organ failure assessment score in risk stratification of sepsis syndromes. Signa Vitae. 2019. 15(1);46-50.
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