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Original Research

Open Access

Using age, arterial lactate level and sequential organ failure assessment score in risk stratification of sepsis syndromes


1Critical Care Medicine Department – Alexandria University, Egypt

2 Clinical Pharmacy and Pharmacy Practice Department – Damanhour University, Egypt

DOI: 10.22514/SV151.042019.6 Vol.15,Issue 1,April 2019 pp.46-50

Published: 23 April 2019

*Corresponding Author(s): AMR ELMORSI E-mail:


Introduction: In low income countries, ICU places are limited and not all sepsis patients will benefit from ICU admission. Stratification is an important step to iden-tify patients who require ICU treatment from patients who can be treated on gen-eral ward setting. Improper stratification results in increased length of stay, costs, morbidity and mortality. Objective: The aim of this study was to stratify the risk of mortality in patients with sepsis syn-drome using age, arterial lactate level and SOFA score. Methods: In this prospective observational study, 250 patients with sepsis were enrolled and followed up un-til discharge. They were categorized into 2 groups according to 7-days mortality. Re-sults: SOFA score (≥5) was the only good tool (AUC=0.722) while age (≥65 years) (AUC=0.650) and arterial lactate (≥3.25 mmol/L) (0.690) were fair tools to predict 7-days mortality. A new score “ALSOFA score” (≥10) was an excellent tool for pre-diction (AUC =0.912, 95%CI: 0.851 to 0.940, p<0.0001). It showed an excellent sensitivity (90.9%) and specificity (85.1%). Conclusion: In critically ill patients with sepsis syndromes, age, arterial lactate and SOFA score are fair tools of stratification. No single marker/score can be used alone to stratify such patients.


Emergency, Critical, Sepsis, SOFA, Arterial Lactate, Stratification

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AMR ELMORSI,AMR DAHROUG,ENAL FAHMY,ISLAM AHMED. Using age, arterial lactate level and sequential organ failure assessment score in risk stratification of sepsis syndromes. Signa Vitae. 2019. 15(1);46-50.


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