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Case Report

Open Access

Atypical Cerebral Infarction in a Patient Suspected Ingestion of Synthetic Cannabinoids


1Department of Emergency Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea

2 Department of Emergency Medicine, Chung-Ang University, College of Medicine, Seoul, Korea

DOI: 10.22514/SV152.092019.11 Vol.15,Issue 2,September 2019 pp.67-69

Published: 20 September 2019

*Corresponding Author(s): YOON HEE CHOI E-mail:


Background. Synthetic cannabinoids are recreational street drugs with many known adverse effects.

Case presentation. Here we present the case of an atypical cerebral infarction in a patient with a suspected ingestion of syn-thetic cannabinoids.

Conclusion. Although synthetic cannabi-noids use is not conventionally associated with stroke, some case reports describe cerebral infarction and myocardial in-farction with significant synthetic can-nabinoids intake. Emergency physicians should know the association of synthetic cannabinoids with seizures, myocardial in-farction, and now possibly ischemic stroke.


stroke; cannabinoids; synthetic cannabinoids; case report 

Cite and Share

JAE HEE LEE,KEON KIM,DONG HOON LEE,YOON HEE CHOI. Atypical Cerebral Infarction in a Patient Suspected Ingestion of Synthetic Cannabinoids. Signa Vitae. 2019. 15(2);67-69.


1. Seely KA, Prather PL, James LP, Moran JH. Marijuana-based drugs: innovative therapeutics or designer drugs of abuse? Mol Interv 2011;11(1):36-51.

2. Lapoint J, James LP, Moran CL, Nelson LS, Hoffman RS, Moran JH. Severe toxicity following synthetic cannabinoid ingestion. Clin Toxicol (Phila) 2011;49(8):760-4.

3. Freeman MJ, Rose DZ, Myers MA, Gooch CL, Bozeman AC, Burgin WS. Ischemic stroke after use of the synthetic marijuana "spice". Neurology 2013;81(24):2090-3.

4. Dresen S, Ferreiros N, Putz M, Westphal F, Zimmermann R, Auwarter V. Monitoring of herbal mixtures potentially containing syn-thetic cannabinoids as psychoactive compounds. J Mass Spectrom. 2010;45(10):1186-94.

5. Adams IB, Martin BR. Cannabis: pharmacology and toxicology in animals and humans. Addiction 1996;91(11):1585-614.

6. Wolff V, Armspach JP, Lauer V, Rouyer O, Bataillard M, Marescaux C, et al. Cannabis-related stroke: myth or reality? Stroke 2013;44(2):558-63.

7. Ince B, Benbir G, Yuksel O, Koseoglu L, Uluduz D. Both hemorrhagic and ischemic stroke following high doses of cannabis con-sumption. Presse Med 2015;44(1):106-7.

8. Golcuk Y, Golcuk B, Sozen S. Effect of regular marijuana smoking on platelet function. Am J Emerg Med 2015;33(5):721-2.

9. Goyal H, Awad HH, Ghali JK. Role of cannabis in cardiovascular disorders. J Thorac Dis 2017;9(7):2079-92.

10. Wolff V, Jouanjus E. Strokes are possible complications of cannabinoids use. Epilepsy Behav 2017;70(Pt B):355-63.

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