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Ibuprofen safety at the golden anniversary. A commentary and recent developments

  • Giustino Varrassi1
  • Joseph V. Pergolizzi2

1Paolo Procacci Foundation, Via Tacito 7, 00193, Roma, Italy

2NEMA Research, Inc., Naples, Florida, United States of America

DOI: 10.22514/sv.2020.16.0097 Vol.17,Issue 2,March 2021 pp.1-3

Published: 08 March 2021

*Corresponding Author(s): Giustino Varrassi E-mail:


Ibuprofen is a long lasting non-steroidal anti-inflammatory drugs (NSAIDs) and still represents one of the most diffused analgesics around the world. It has an interesting story started over 50 years ago. In this short comment to an already published paper, the authors try to focus some specific important point. On top, they illustrate the recent, confusing and fake assertion on the potentially dangerous influence that ibuprofen could have, increasing the risk of Coronavirus infection. This is also better illustrated in a previously published paper, where the readers could find more clear responses to eventual doubts.


NSAIDs; Ibuprofen; COVID-19; Side effects

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Giustino Varrassi,Joseph V. Pergolizzi. Ibuprofen safety at the golden anniversary. A commentary and recent developments. Signa Vitae. 2021. 17(2);1-3.


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