The analgesic effect of erector spinae plane block in thoracic surgery: a systematic review and meta-analysis of randomized controlled trials
1Department of Anesthesiology, Yongchuan aﬃliated Hospital of Chongqing Medical University, 402160 Yongchuan, Chongqing, China
Submitted: 07 May 2021 Accepted: 08 June 2021
Online publish date: 08 July 2021
Objectives: The aim of this study is to evaluate the analgesic effect of erector spinae plane block (ESPB) in patients undergoing thoracic surgery.
Methods: We systematically searched Embase, PubMed, The Cochrane Library, VIP database, CNKI, Wanfang database, CBM, from 2010 to December, 2020 to perform a meta-analysis of randomized controlled trials (RCTs) on the analgesic effect of ESPB in thoracic surgery patients. The primary outcome were postoperative pain scores at various time points.
Results: Eighteen studies with a total of 1303 patients were included. The meta-analysis found that ESPB reduced postoperative 48-hour pain scores at rest or movement at different time points compared with the control group, reduced the incidence of postoperative nausea and vomiting (PONV) (odds ratio, OR = 0.48, 95% CI = 0.33∼0.71, P < 0.05), and reduced the number of patient-controlled intravenous analgesia (PCIA) pressing times (mean difference, MD = −6.83, 95% CI = −8.73∼−4.94, P < 0.05).
Conclusions: Compared with general anesthesia (GA), GA combined with ESPB significantly decreases postoperative pain, PONV and opioids requirements following thoracic surgery.
Erector spinae plane block; Thoracic surgery; Analgesia; Meta-analysis; Randomized controlled trial
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