Point-of-care testing as the future of pre-hospital emergency medicine: an overview
1Institute of Outcomes Research, Maria Sklodowska-Curie Medical Academy, 03-411 Warsaw, Poland
2Research Unit, Maria Sklodowska-Curie Bialystok Oncology Center, 15-027 Bialystok, Poland
3Department of Emergency, Fatebenefratelli Hospital, ASST Fatebenefratelli and Sacco, 20121 Milan, Italy
4Research Unit, Polish Society of Disaster Medicine, 05-806 Warsaw, Poland
5Department of Community Medicine, College of Medicine, University of Ibadan, 200212 Ibadan, Oyo State, Nigeria
6Department of Community Medicine, University College Hospital, 200212 Ibadan, Oyo State, Nigeria
7Post-graduate School of Occupational Health, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
8Health Service Department, Italian State Police, Ministry of Interior, Italy
DOI: 10.22514/sv.2021.241 Vol.18,Issue 3,May 2022 pp.153-157
Submitted: 27 August 2021 Accepted: 22 October 2021
Published: 08 May 2022
*Corresponding Author(s): Francesco CHIRICO E-mail: firstname.lastname@example.org
Point-of-care testing (POCT) plays an increasingly important role in pre-emergency medicine by ensuring that patient’s continuum of care is commenced before arrival at health facilities. Given the benefits of POCT during the COVID-19 pandemic, this commentary described the advantages and disadvantages of POCT, and its current practices in pre-hospital emergency medicine. Point-of-care tests are easy to operate, cost-effective, and yield quick and accurate response, but are posed with challenges such as safety errors, poor adherence to quality control standards, and inspection errors. To optimize the benefits of POCT in pre-emergency medicine, it is required that regular trainings are conducted for POCT operators, and total compliance to POCT handling and management guidelines should be considered by each POCT operator.
COVID-19; Emergency care; Emergency medicine; Point-of-care testing; Laboratory tests
Lukasz SZARPAK,Gabriella NUCERA,Michal PRUC,Olayinka Stephen ILESANMI,Aanuoluwapo Adeyimika AFOLABI,Francesco CHIRICO. Point-of-care testing as the future of pre-hospital emergency medicine: an overview. Signa Vitae. 2022. 18(3);153-157.
 Blanchard IE, Kozicky R, Dalgarno D, Simms J, Goulder S, Williamson TS, et al. Community paramedic point of care testing: validity and usability of two commercially available devices. BMC Emergency Medicine. 2019; 19: 30.
 Möckel M, Searle J. Point-of-care testing in preclinical emergency medicine. Medizinische Klinik - Intensivmedizin und Notfallmedizin. 2014; 109: 100–103. (In German)
 Tripoliti EE, Ioannidou P, Toumpaniaris P, Rammos A, Pacitto D, Lourme J, et al. Point-of-Care Testing Devices for Heart Failure Analyzing Blood and Saliva Samples. IEEE Reviews in Biomedical Engineering. 2020; 13: 17–31.
 Patel K, Suh-Lailam BB. Implementation of point-of-care testing in a pediatric healthcare setting. Critical Reviews in Clinical Laboratory Sciences. 2019; 56: 239–246.
 Unemo M, Bradshaw CS, Hocking JS, de Vries HJC, Francis SC, Mabey D, et al. Sexually transmitted infections: challenges ahead. The Lancet Infectious Diseases. 2017; 17: e235–e279.
 Udugama B, Kadhiresan P, Kozlowski HN, Malekjahani A, Osborne M, Li VYC, et al. Diagnosing COVID-19: The Disease and Tools for Detection. ACS Nano. 2020; 14: 3822–3835.
 Ilesanmi OS, Afolabi AA. COVID-19 waves in Africa: Effects of outbreak response and interventions. Global Biosecurity. 2021; 3.
 World Health Organization. Antigen-detection in the diagnosis of SARS-CoV-2 infection using rapid immunoassays. 2020. Available at: apps.who.int/iris/bitstream/handle/10665/334253/WHO-2019-nCoV-Antigen_Detection-2020.1-eng.pdf?sequence=1& isAllowed=y2020 (Accessed: 11 September 2021).
 Wu F, Zhao S, Yu B, Chen Y, Wang W, Song Z, et al. A new coronavirus associated with human respiratory disease in China. Nature. 2020; 579: 265–269.
 World Health Organization. WHO coronavirus disease (COVID-19) dashboard. 2021. Available at: https://covid19.who.int/?gclid=Cj0KCQjwz4z3BRCgARIsAES_ OVezBT1BH_I8YhZousdOX0PeMERwgm-YmKNco1F1bpTPcArm6HIgwM0aAigBEALw_wcB (Accessed: 9 February 2021).
 Jung W, Han J, Choi JW, Ahn CH. Point-of-care testing (POCT) diagnostic systems using microfluidic lab-on-a-chip technologies. Micro-electronic Engineering. 2015; 132: 46–57.
 Lisboa Bastos M, Tavaziva G, Abidi SK, Campbell JR, Haraoui LP, Johnston JC, et al. Diagnostic accuracy of serological tests for COVID-19: systematic review and meta-analysis. British Medical Journal. 2020; 370: m2516.
 Florkowski C, Don-Wauchope A, Gimenez N, Rodriguez-Capote K, Wils J, Zemlin A. Point-of-care testing (POCT) and evidence-based laboratory medicine (EBLM) - does it leverage any advantage in clinical decision making? Critical Reviews in Clinical Laboratory Sciences. 2017; 54: 471–494.
 Dahm MR, McCaughey E, Li L, Westbrook J, Mumford V, Iles-Mann J, et al. Point-of-Care Testing across Rural and Remote Emergency Departments in Australia: Staff Perceptions of Operational Impact. Studies in Health Technology and Informatics. 2017; 239: 28–34.
 Sørensen JT, Terkelsen CJ, Steengaard C, Lassen JF, Trautner S, Christensen EF, et al. Prehospital troponin T testing in the diagnosis and triage of patients with suspected acute myocardial infarction. Journal of the American College of Cardiology. 2011; 107: 1436–1440.
 Cantero M, Redondo M, Martín E, Callejón G, Hortas ML. Use of quality indicators to compare point-of-care testing services in a neonatal unit and errors in a STAT central laboratory. Clinical Chemistry and Laboratory Medicine. 2015; 53: 239–247.
 O’Kane MJ, McManus P, McGowan N, Lynch PLM. Quality error rates in point-of-care testing. Clinical Chemistry. 2011; 57: 1267–1271.
 Shaw JLV. Practical challenges related to point of care testing. Practical Laboratory Medicine. 2016; 4: 22–29.
 Schober P, Bossers SM, Koolwijk J, Terra M, Schwarte LA. Prehospital coagulation measurement by a portable blood analyzer in a helicopter emergency medical service (HEMS). The American Journal of Emer-gency Medicine. 2021; 46: 137–140.
 Marquardt U, Apau D. Point-of-care D-dimer testing in emergency departments. Emergency Nurse. 2015; 23: 29–35.
 Ayouba A, Mbala-Kingebeni P, Keita AK, Vidal N, Lacroix A, Touré A, et al. New technologies for controlling emerging infectious diseases in Guinea and the Democratic Republic of the Congo: their role in response to the Ebola epidemic. Medecine et Sante Tropicales. 2019; 29: 362–365.
 Venturini JM, Stake CE, Cichon ME. Prehospital point-of-care testing for troponin: are the results reliable? Prehospital Emergency Care. 2012; 17: 88–91.
 Beynon C, Erk AG, Potzy A, Mohr S, Popp E. Point of care coagulometry in prehospital emergency care: an observational study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2015; 23: 58.
 Carron PN, Taffe P, Ribordy V, Schoettker P, Fishman D, Yersin B. Accuracy of prehospital triage of trauma patients by emergency physicians: a retrospective study in western Switzerland. European Journal of Emergency Medicine. 2011; 18: 86–93.
 Shakur H, Roberts I, Bautista R, Caballero J, Coats T, Dewan Y, et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. The Lancet. 2010; 376: 23–32.
 Hagemo JS. Prehospital detection of traumatic coagulopathy. Transfusion. 2013; 53: 48S–51S.
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