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Original Research

Open Access

Comparison of volume assessment methods in transurethral resection of the prostate

  • Ying Wang1
  • Fei Gao2
  • Xiaochun Zheng2

1Department of Anaesthesiology, Fujian Medical University Teaching Hospital, Fujian Provincial Geriatric Hospital, 350003 Fuzhou, China

2Department of Anaesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, 350004 Fuzhou, China

DOI: 10.22514/sv.2022.023

Submitted: 24 October 2021 Accepted: 18 January 2022

Online publish date: 22 March 2022

*Corresponding Author(s): Xiaochun Zheng E-mail:


To compare the value of inferior vena cava (IVC) variation, thoracic fluid content (TFC), and central venous pressure (CVP) in transurethral resection of the prostate (TURP) for systemic volumetric load. Eighty male patients who had undergone TURP at our hospital from July to August 2021 were enrolled. Before and after anesthesia induction, IVC variation and TFC were recorded every 15 min and then 15 min after surgery. The ability of IVC variation, TFC, and CVP to predict fluid responsiveness was assessed using receiver operator characteristic (ROC) curves. The Pearson correlation test was used to analyze the correlations among intraoperative IVC variation, TFC, CVP and the stroke volume index (SVI). ROC curve evaluation: the area under the ROC curve (AUC) of IVC variation was 0.82 (p < 0.01), while that of CVP and TFC was 0.61 (p = 0.16) and 0.45 (p = 0.28), respectively. Since the operation began, ∆IVC variation showed a significant negative correlation with ∆SVI at different time points. ∆CVP and ∆TFC showed a poor correlation with ∆SVI. IVC variation was superior to TFC and CVP to predict fluid responsiveness and assess the volume status and volume responsiveness of patients undergoing TURP.


Transurethral resection of the prostate; IVC variation; Thoracic fluid content; Central venous pressure; Systemic volumetric load

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Ying Wang,Fei Gao,Xiaochun Zheng. Comparison of volume assessment methods in transurethral resection of the prostate. Signa Vitae. 2022.doi:10.22514/sv.2022.023.


[1] Staelens A, Tomsin K, Grieten L, Oben J, Mesens T, Spaanderman M, et al. Non-invasive assessment of gestational hemodynamics: benefits and limitations of impedance cardiography versus other techniques. Expert Review of Medical Devices. 2013; 10: 765–779.

[2] Yao B, Liu JY, Sun YB, Zhao YX, Li LD. The value of the inferior vena cava area distensibility index and its diameter ratio for predicting fluid responsiveness in mechanically ventilated patients. Shock. 2019; 52: 37–42.

[3] Zhang X, Feng J, Zhu P, Luan H, Wu Y, Zhao Z. Ultrasonographic measurements of the inferior vena cava variation as a predictor of fluid responsiveness in patients undergoing anesthesia for surgery. Journal of Surgical Research. 2016; 204: 118–122.

[4] Khwannimit B, Bhurayanontachai R. Prediction of fluid responsiveness in septic shock patients: comparing stroke volume variation by Flo-Trac/Vigileo and automated pulse pressure variation. European Journal of Anaesthesiology. 2012; 29: 64–69.

[5] Renner J, Broch O, Duetschke P, Scheewe J, Höcker J, Moseby M, et al. Prediction of fluid responsiveness in infants and neonates undergoing congenital heart surgery. British Journal of Anaesthesia. 2012; 108: 108–115.

[6] Itoh S, Arai M, Kuroiwa M, Ando H, Okamoto H. Effect of preoperative oral rehydration on the hypotension during spinal anesthesia. Masui. 2016; 65: 786–789. (In Japanese)

[7] Marchioni M, Cindolo L, Di Nicola M, Schips L, De Sio M, Lima E, et al. Major acute cardiovascular events after transurethral prostate surgery: a population-based analysis. Urology. 2019; 131: 196–203.

[8] Chatti R, de Rudniki S, Marqué S, Dumenil AS, Descorps-Declère A, Cariou A, et al. Comparison of two versions of the Vigileo-FloTrac system (1.03 and 1.07) for stroke volume estimation: a multicentre, blinded comparison with oesophageal doppler measurements. British Journal of Anaesthesia. 2009; 102: 463–469.

[9] Marx G, Cope T, McCrossan L, Swaraj S, Cowan C, Mostafa SM, et al. Assessing fluid responsiveness by stroke volume variation in mechanically ventilated patients with severe sepsis. European Journal of Anaesthesiology. 2004; 21: 132–138.

[10] Bennett VA, Cecconi M. Perioperative fluid management: from physiol-ogy to improving clinical outcomes. Indian Journal of Anaesthesia. 2017; 61: 614–621.

[11] Dipti A, Soucy Z, Surana A, Chandra S. Role of inferior vena cava diameter in assessment of volume status: a meta-analysis. The American Journal of Emergency Medicine. 2012; 30: 1414–1419.e1.

[12] Nette RW, Ie EH, Vletter WB, Krams R, Weimar W, Zietse R. Norepinephrine-induced vasoconstriction results in decreased blood volume in dialysis patients. Nephrology Dialysis Transplantation. 2006; 21: 1305–1311.

[13] Beaulieu Y. Bedside echocardiography in the assessment of the critically ill. Critical Care Medicine. 2007; 35: S235–S249.

[14] Zengin S, Al B, Genc S, Yildirim C, Ercan S, Dogan M, et al. Role of inferior vena cava and right ventricular diameter in assessment of volume status: a comparative study: ultrasound and hypovolemia. The American Journal of Emergency Medicine. 2013; 31: 763–767.

[15] Ferrada P, Anand RJ, Whelan J, Aboutanos MA, Duane T, Malhotra A, et al. Qualitative assessment of the inferior vena cava: useful tool for the evaluation of fluid status in critically ill patients. The American Surgeon. 2012; 78: 468–470.

[16] Stawicki SP, Braslow BM, Panebianco NL, Kirkpatrick JN, Gracias VH, Hayden GE, et al. Intensivist use of hand-carried ultrasonography to measure IVC collapsibility in estimating intravascular volume status: correlations with CVP. Journal of the American College of Surgeons. 2009; 209: 55–61.

[17] Zhang Z, Xu X, Ye S, Xu L. Ultrasonographic measurement of the respiratory variation in the inferior vena cava diameter is predictive of fluid responsiveness in critically ill patients: systematic review and meta-analysis. Ultrasound in Medicine & Biology. 2014; 40: 845–853.

[18] Sundaram SC, Salins SR, Kumar AN, Korula G. Intra-operative fluid management in adult neurosurgical patients undergoing intracranial tumour surgery: randomised control trial comparing pulse pressure variance (PPV) and central venous pressure (CVP). Journal of Clinical and Diagnostic Research. 2016; 10: UC01–UC05.

[19] Sakka SG, Klein M, Reinhart K, Meier-Hellmann A. Prognostic value of extravascular lung water in critically ill patients. Chest. 2002; 122: 2080–2086.

[20] Galas A, Krzesiński P, Gielerak G, Piechota W, Uziębło-Życzkowska B, Stańczyk A, et al. Complex assessment of patients with decompensated heart failure: the clinical value of impedance cardiography and N-terminal pro-brain natriuretic peptide. Heart Lung. 2019; 48: 294–301.

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