Article Data

  • Views 2277
  • Dowloads 219

Original Research

Open Access

Decision-making and treatment results of complex proximal humeral fractures in geriatric patients: retrospective study from a level 1 trauma centre

  • Miha Ambrožič1,*,
  • Rok Bergman1
  • Luka Hodnik1
  • Roman Luštrik2
  • Franc Štefanič1
  • Matej Cimerman1
  • Ladislav Kovačič3

1Department of traumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia

2Private statistical practice, Biolitika, Statistical analysis and consulting, Podgorska cesta 30, 1210 Ljubljana, Slovenia

3Private orthopaedic practice, Arbor Mea Medical d.o.o., Savska cesta 10, 1000 Ljubljana, Slovenia

DOI: 10.22514/sv.2022.040 Vol.19,Issue 1,January 2023 pp.101-116

Submitted: 01 November 2021 Accepted: 16 February 2022

Published: 08 January 2023

*Corresponding Author(s): Miha Ambrožič E-mail: miha.ambrozic@gmail.com

Abstract

Proximal humeral fractures are common in elderly, but despite the high incidence, optimal treatment is still discussed and remains a topic of controversy. Nonoperative treatment continuous to be the main modality. However, due to advancements in surgical technology with new techniques and implants, operative treatment could lead to better outcomes and less complications, even in older patients. Decision-making in elderly should incorporate comorbidities, activity level and patient expectations. This study was performed with the intention to find out, if there is a significant difference in treatment strategy and number of operations, in the last five years. Patients older than 65 years with proximal humeral fractures were included. Retrospective analysis of radiographic material and post-injury data was performed, from patients treated in 2015, 2019 and 2020. Last two years were also compared separately to exclude the effect of Coronavirus disease 2019 (COVID-19) pandemic. Epidemiological data assessment, fracture type and treatment strategy were analysed for corresponding years. Statistical analysis was focused on complex three-and four-part fractures. There were no statistically significant differences regarding incidence between the analysed years. Low energy fall was the mechanism of injury in majority of patients. Patients with tuberosity fractures were in average younger than patients in other groups. Although there were more computed tomography (CT) scans done in younger elderly patients, there was no significant difference in number of CTs compared to older patients (year 2015: p = 0.246; year 2019: p = 0.710, year 2020: p = 0.849). The number of operative interventions was the lowest in 2019 (p = 0.498) and the same was for the osteosynthesis using intramedullary nails (p = 0.014). Frequency of reversed shoulder arthroplasty surgeries is increasing, but the difference is not significant (p = 0.390). Both operative and nonoperative treatment result in similar range of motion (ROM) measurements (p = 0.164 for anteflexion. p = 0.163 for abduction), however the groups were not comparable regarding exact fracture types. In the analysed period of 5 years, epidemiology and treatment strategy of proximal humeral fractures did not change. Nonoperative approach remained the main treatment modality. No significant difference was noted in number of interventions or implants used, although there seemed to be an increased trend towards treatment with reverse shoulder arthroplasty (RSA) in complex fractures. A strong correlation was observed between radiographic indications for conservative treatment and actual implementation of it. However, when surgical treatment was indicated using the same radiological criteria, there were more than half of patients, who were not operated on. Radiologic indications are thus not enough for decision-making in treatment of three- and four-part fractures, and patient factors, such as comorbidities and pre-injury activity level, play a major role.


Keywords

Proximal humeral fractures; Elderly; Surgery vs. conservative; Intramedullary nailing; Locking plate; Shoulder arthroplasty; COVID-19 pandemic


Cite and Share

Miha Ambrožič,Rok Bergman,Luka Hodnik,Roman Luštrik,Franc Štefanič,Matej Cimerman,Ladislav Kovačič. Decision-making and treatment results of complex proximal humeral fractures in geriatric patients: retrospective study from a level 1 trauma centre. Signa Vitae. 2023. 19(1);101-116.

References

[1] Passaretti D, Candela V, Sessa P, Gumina S. Epidemiology of proximal humeral fractures: a detailed survey of 711 patients in a metropolitan area. Journal of Shoulder and Elbow Surgery. 2017; 26: 2117–2124.

[2] Court-Brown CM, Caesar B. Epidemiology of adult fractures: a review. Injury. 2006; 37: 691–697.

[3] Launonen AP, Lepola V, Saranko A, Flinkkilä T, Laitinen M, Mattila VM. Epidemiology of proximal humerus fractures. Archives of Osteoporosis. 2015; 10: 209.

[4] Lauritzen JB, Schwarz P, Lund B, McNair P, Transbøl I. Changing incidence and residual lifetime risk of common osteoporosis-related fractures. Osteoporosis International. 1993; 3: 127–132.

[5] Han RJ, Sing DC, Feeley BT, Ma CB, Zhang AL. Proximal humerus fragility fractures: recent trends in nonoperative and operative treatment in the Medicare population. Journal of Shoulder and Elbow Surgery. 2016; 25: 256–261.

[6] Widnall JC, Dheerendra SK, Malal JJG, Waseem M. Proximal humeral fractures: a review of current concepts. The Open Orthopaedics Journal. 2013; 7: 361–365.

[7] Schumaier A, Grawe B. Proximal humerus fractures: evaluation and management in the elderly patient. Geriatric Orthopaedic Surgery & Rehabilitation. 2018; 9: 215145851775051.

[8] Bhat SB, Secrist ES, Austin LS, Getz CL, Krieg JC, Mehta S, et al. Displaced proximal humerus fractures in older patients: shoulder surgeons versus traumatologists. Orthopedics. 2016; 39: e509–513.

[9] Jo MJ, Gardner MJ. Proximal humerus fractures. Current Reviews in Musculoskeletal Medicine. 2012; 5: 192–198.

[10] Spross C, Zeledon R, Zdravkovic V, Jost B. How bone quality may influence intraoperative and early postoperative problems after angular stable open reduction-internal fixation of proximal humeral fractures. Journal of Shoulder and Elbow Surgery. 2017; 26: 1566–1572.

[11] Jung S, Shim S, Kim H, Lee J, Lim H. Factors that influence reduction loss in proximal humerus fracture surgery. Journal of Orthopaedic Trauma. 2015; 29: 276–282.

[12] Maier D, Jaeger M, Izadpanah K, Strohm PC, Suedkamp NP. Proximal humeral fracture treatment in adults. Journal of Bone and Joint Surgery. 2014; 96: 251–261.

[13] Mease SJ, Kraeutler MJ, Gonzales-Luna DC, Gregory JM, Gardner MJ, Choo AM. Current controversies in the treatment of geriatric proximal humeral fractures. Journal of Bone and Joint Surgery. 2021; 103: 829–836.

[14] Schairer WW, Nwachukwu BU, Lyman S, Gulotta LV. Arthroplasty treatment of proximal humerus fractures: 14-year trends in the United States. The Physician and Sportsmedicine. 2017; 45: 92–96.

[15] R Core Team. R: A language and environment for statistical computing. 2021. Available at: https://www.Rproject.org (Accessed: 14 October 2021).

[16] Wickham H, Bryan J. readxl: Read Excel Files. R package version 1.3.1. 2019. Available at: https://CRAN.R-project.org/package= readxl (Accessed: 14 October 2021).

[17] Wickham H. ggplot2: Elegant Graphics for Data Analysis. 2nd edn. SpringerVerlag: New York, USA. 2016.

[18] Hessmann MH, Hansen WSM, Krummenauer F, Pol TF, Rommens M. Locked plate fixation and intramedullary nailing for proximal humerus fractures: a biomechanical evaluation. The Journal of Trauma: Injury, Infection, and Critical Care. 2005; 58: 1194–1201.

[19] Siffri PC, Peindl RD, Coley ER, Norton J, Connor PM, Kellam JF. Biomechanical analysis of blade plate versus locking plate fixation for a proximal humerus fracture: comparison using cadaveric and synthetic humeri. Journal of Orthopaedic Trauma. 2006; 20: 547–554.

[20] Zhang W, Zeng L, Liu Y, Pan Y, Zhang W, Zhang C, et al. The Mechanical benefit of medial support screws in locking plating of proximal humerus fractures. PLoS One. 2014; 9: e103297.

[21] Tieland M, Trouwborst I, Clark BC. Skeletal muscle performance and ageing. Journal of Cachexia, Sarcopenia and Muscle. 2018; 9: 3–19.

[22] Clement ND, Duckworth AD, McQueen MM, Court-Brown CM. The outcome of proximal humeral fractures in the elderly. the Bone & Joint Journal. 2014; 96: 970–977.

[23] McLean AS, Price N, Graves S, Hatton A, Taylor FJ. Nationwide trends in management of proximal humeral fractures: an analysis of 77,966 cases from 2008 to 2017. Journal of Shoulder and Elbow Surgery. 2019; 28: 2072–2078.

[24] Rosas S, Law TY, Kurowicki J, Formaini N, Kalandiak SP, Levy JC. Trends in surgical management of proximal humeral fractures in the Medicare population: a nationwide study of records from 2009 to 2012. Journal of Shoulder and Elbow Surgery. 2016; 25: 608–613.

[25] Court-Brown CM, Cattermole H, McQueen MM. Impacted valgus fractures (B1.1) of the proximal humerus. The Journal of Bone and Joint Surgery. British Volume. 2002; 84: 504–508.

[26] Soler-Peiro M, García-Martínez L, Aguilella L, Perez-Bermejo M. Conservative treatment of 3-part and 4-part proximal humeral fractures: a systematic review. Journal of Orthopaedic Surgery and Research. 2020; 15: 347.

[27] Carofino BC, Leopold SS. Classifications in brief: the neer classification for proximal humerus fractures. Clinical Orthopaedics & Related Research. 2013; 471: 39–43.

[28] Voigt C, Kreienborg S, Megatli O, Schulz A, Lill H, Hurschler C. How does a varus deformity of the humeral head affect elevation forces and shoulder function? a biomechanical study with human shoulder specimens. Journal of Orthopaedic Trauma. 2011; 25: 399–405.

[29] Braunstein V, Wiedemann E, Plitz W, Muensterer OJ, Mutschler W, Hinterwimmer S. Operative treatment of greater tuberosity fractures of the humerus—a biomechanical analysis. Clinical Biomechanics. 2007; 22: 652–657.

[30] Goch AM, Christiano A, Konda SR, Leucht P, Egol KA. Operative repair of proximal humerus fractures in septuagenarians and octogenarians: does chronologic age matter? Journal of Clinical Orthopaedics and Trauma. 2017; 8: 50–53.

[31] Rangan A, Handoll H, Brealey S, Jefferson L, Keding A, Martin BC, et al. Surgical vs. nonsurgical treatment of adults with displaced fractures of the proximal humerus. JAMA. 2015; 313: 1037.

[32] Bell J, Leung BC, Spratt KF, Koval KJ, Weinstein JD, Goodman DC, et al. Trends and variation in incidence, surgical treatment, and repeat surgery of proximal humeral fractures in the elderly. The Journal of Bone and Joint Surgery. 2011; 93: 121–131.

[33] Little MTM, Berkes MB, Schottel PC, Lazaro LE, LaMont LE, Pardee NC, et al. The impact of preoperative coronal plane deformity on proximal humerus fixation with endosteal augmentation. Journal of Orthopaedic Trauma. 2014; 28: 338–347.

[34] Kim D, Lee D, Chun Y, Shin S. Which additional augmented fixation procedure decreases surgical failure after proximal humeral fracture with medial comminution: fibular allograft or inferomedial screws? Journal of Shoulder and Elbow Surgery. 2018; 27: 1852–1858.

[35] Lee SH, Han SS, Yoo BM, Kim JW. Outcomes of locking plate fixation with fibular allograft augmentation for proximal humeral fractures in osteoporotic patients. The Bone & Joint Journal. 2019; 101: 260–265.

[36] Matassi F, Angeloni R, Carulli C, Civinini R, Di Bella L, Redl B, et al. Locking plate and fibular allograft augmentation in unstable fractures of proximal humerus. Injury. 2012; 43: 1939–1942.

[37] Neviaser AS, Hettrich CM, Beamer BS, Dines JS, Lorich DG. Endosteal strut augment reduces complications associated with proximal humeral locking plates. Clinical Orthopaedics & Related Research. 2011; 469: 3300–3306.

[38] Sun Q, Ge W, Li G, Wu J, Lu G, Cai M, et al. Locking plates versus intramedullary nails in the management of displaced proximal humeral fractures: a systematic review and meta-analysis. International Orthopaedics. 2018; 42: 641–650.

[39] Hertel R, Hempfing A, Stiehler M, Leunig M. Predictors of humeral head ischemia after intracapsular fracture of the proximal humerus. Journal of Shoulder and Elbow Surgery. 2004; 13: 427–433.

[40] Postacchini R, Castagna A, Borroni M, Cinotti G, Postacchini F, Gumina S. Total shoulder arthroplasty for the treatment of failed hemiarthroplasty in patients with fracture of the proximal humerus. Journal of Shoulder and Elbow Surgery. 2012; 21: 1542–1549.

[41] Al-Hadithy N, Furness N, Patel R, Jonas S, Jobbagy A, Lowdon I, et al. Cementless surface replacement hemiarthroplasty for primary glenohumeral osteoarthritis: results of over 5-year follow-up in patients with or without rotator cuff deficiency. Shoulder & Elbow. 2015; 7: 237–243.

[42] Solberg BD, Moon CN, Franco DP, Paiement GD. Surgical treatment of three and four-part proximal humeral fractures. the Journal of Bone and Joint Surgery. 2009; 91: 1689–1697.

[43] Sebastiá-Forcada E, Cebrián-Gómez R, Lizaur-Utrilla A, Gil-Guillén V. Reverse shoulder arthroplasty versus hemiarthroplasty for acute proximal humeral fractures. a blinded, randomized, controlled, prospective study. Journal of Shoulder and Elbow Surgery. 2014; 23: 1419–1426.

[44] Austin DC, Torchia MT, Cozzolino NH, Jacobowitz LE, Bell J. Decreased reoperations and improved outcomes with reverse total shoulder arthroplasty in comparison to hemiarthroplasty for geriatric proximal humerus fractures: a systematic review and meta-analysis. Journal of Orthopaedic Trauma. 2019; 33: 49–57.

[45] Gallinet D, Cazeneuve J, Boyer E, Menu G, Obert L, Ohl X, et al. Reverse shoulder arthroplasty for recent proximal humerus fractures: Outcomes in 422 cases. Orthopaedics & Traumatology: Surgery & Research. 2019; 105: 805–811.

[46] Simovitch RW, Roche CP, Jones RB, Routman HD, Marczuk Y, Wright TW, et al. Effect of tuberosity healing on clinical outcomes in elderly patients treated with a reverse shoulder arthroplasty for 3- and 4-part proximal humerus fractures. Journal of Orthopaedic Trauma. 2019; 33: e39–e45.

[47] Boileau P, Alta TD, Decroocq L, Sirveaux F, Clavert P, Favard L, et al. Reverse shoulder arthroplasty for acute fractures in the elderly: is it worth reattaching the tuberosities? Journal of Shoulder and Elbow Surgery. 2019; 28: 437–444.

[48] Chun Y, Kim D, Lee D, Shin S. Reverse shoulder arthroplasty for four-part proximal humerus fracture in elderly patients: can a healed tuberosity improve the functional outcomes? Journal of Shoulder and Elbow Surgery. 2017; 26: 1216–1221.

[49] Lopiz Y, Alcobía-Díaz B, Galán-Olleros M, García-Fernández C, Picado AL, Marco F. Reverse shoulder arthroplasty versus nonoperative treatment for 3- or 4-part proximal humeral fractures in elderly patients: a prospective randomized controlled trial. Journal of Shoulder and Elbow Surgery. 2019; 28: 2259–2271.

[50] Chivot M, Lami D, Bizzozero P, Galland A, Argenson JN. Three- and four-part displaced proximal humeral fractures in patients older than 70 years: reverse shoulder arthroplasty or nonsurgical treatment? Journal of Shoulder and Elbow Surgery. 2019; 28: 252–259.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.

Index Copernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.

Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.

Scopus: CiteScore 1.0 (2022) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.

Submission Turnaround Time

Conferences

Top