Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Antiandrogen activity of drugs for COVID-19. The case of sabizabulin
1Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy
2School of Medicine, Vita-Salute San Raffaele University, 20132 Milan, Italy
3Department of Intensive Care Medicine, Kameda Medical Center, 296-8602 Kamogawa, Japan
DOI: 10.22514/sv.2023.027 Vol.19,Issue 3,May 2023 pp.1-3
Submitted: 13 August 2022 Accepted: 18 October 2022
Published: 08 May 2023
*Corresponding Author(s): Giovanni Landoni E-mail: landoni.giovanni@hsr.it
Yuki Kotani,Beatrice Righetti,Mary Ann Belli,Giovanni Landoni. Antiandrogen activity of drugs for COVID-19. The case of sabizabulin. Signa Vitae. 2023. 19(3);1-3.
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[7] Davey RA, Grossmann M. Androgen receptor structure, function and biology: from bench to bedside. Clinical Biochemist Reviews. 2016; 37: 3–15.
[8] Montopoli M, Zumerle S, Vettor R, Rugge M, Zorzi M, Catapano CV, et al. Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (N = 4532). Annals of Oncology. 2020; 31: 1040–1045.
[9] Lyon M, Li J, Cullen J, Milinovich A, Kattan M, Jehi L, et al. 5α-reductase inhibitors are associated with reduced risk of SARS-CoV-2 infection: a matched-pair, registry-based analysis. Journal of Urology. 2022; 207: 183–189.
[10] Zangrillo A, Morselli F, Biagioni E, Di Stella R, Coloretti I, Moizo E, et al. Sex-related mortality differences in young adult septic shock patients. Signa Vitae. 2022; 1–7.
[11] Ghandehari S, Matusov Y, Pepkowitz S, Stein D, Kaderi T, Narayanan D, et al. Progesterone in addition to standard of care vs. standard of care alone in the treatment of men hospitalized with moderate to severe COVID-19. Chest. 2021; 160: 74–84.
[12] Nicastri E, Marinangeli F, Pivetta E, Torri E, Reggiani F, Fiorentino G, et al. A phase 2 randomized, double-blinded, placebo-controlled, multicenter trial evaluating the efficacy and safety of raloxifene for patients with mild to moderate COVID-19. EClinicalMedicine. 2022; 48: 101450.
[13] Cadegiani FA, McCoy J, Gustavo Wambier C, Goren A. Early antiandrogen therapy with dutasteride reduces viral shedding, inflam-matory responses, and time-to-remission in males with COVID-19: a randomized, double-blind, placebo-controlled interventional trial (EAT-DUTA AndroCoV Trial—Biochemical). Cureus. 2021; 13: e13047.
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