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Original Research

Open Access

Interaction effect between prehospital hydration and initial cardiac rhythm in traumatic out-of-hospital cardiac arrest: a nationwide observational study

  • Dae Kon Kim1,2,3
  • Sang Do Shin2,3,4
  • Young Sun Ro2,3,4
  • Kyoung Jun Song2,3,5
  • Joo Jeong2,3,6
  • Ki Jeong Hong2,3,4,*,

1Department of Public Health Care Service, Seoul National University Bundang Hospital, 13620 Seongnam, Republic of Korea

2Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, 03080 Seoul, Republic of Korea

3Department Emergency Medicine, College of Medicine, Seoul National University, 03080 Seoul, Republic of Korea

4Department Emergency Medicine, Seoul National University Hospital, 03080 Seoul, Republic of Korea

5Department Emergency Medicine, Seoul Metropolitan Government Boramae Medical Center, 07061 Seoul, Republic of Korea

6Department Emergency Medicine, Seoul National University Bundang Hospital, 13620 Seongnam, Republic of Korea

DOI: 10.22514/sv.2023.128 Vol.20,Issue 2,February 2024 pp.27-37

Submitted: 15 July 2023 Accepted: 22 August 2023

Published: 08 February 2024

*Corresponding Author(s): Ki Jeong Hong E-mail: ssberg@snu.ac.kr

Abstract

Traumatic cardiac arrest (TCA) is different in etiology compared to medical cardiac arrest. In case of TCA, it is important to initiate early fluid resuscitation. Initial cardiac rhythm serves as an indicator of outcomes in case of cardiac arrest. We aimed to find the association between prehospital hydration and outcomes of TCA according to initial cardiac rhythm. This is a retrospective, observational, cross-sectional study. An examination was undertaken involving patients afflicted with TCA within the timeframe of 2014 to 2019. Exposure was defined to encompass prehospital hydration; interactive exposure was categorized by initial cardiac rhythm (non-shockable vs. shockable); the primary outcome was defined as good neurological status at discharge, whereas the secondary outcome was defined as survival to discharge. Multivariable logistic regression analysis was used to calculate adjusted odds ratios (AORs) with 95% confidence intervals (CIs). A comprehensive analysis was conducted on a cumulative of 20,247 patients. Rates of good neurological status and survival to discharge were 0.2% and 8.3% (non-shockable rhythm group) and 3.0% and 16.7%(shockable rhythm group), respectively. However, rates of good neurological status and survival to discharge were 0.2% and 7.9% (non-prehospital hydration group) and 0.3% and 10.0% (hydration group), respectively. Compared to the non-hydration group, the AORs for good neurological status at discharge was 1.44 (95% CI: 0.77–2.69) for the hydration group. Moreover, compared to the non-shockable rhythm group, the AORs for good neurological status at discharge was 19.74 (95% CI: 10.46–27.26) in the shockable rhythm group. The interaction analysis conducted between prehospital hydration and initial rhythm unveiled the efficacy of prehospital hydration in promoting favorable survival to discharge outcomes in the non-shockable rhythm group. Therefore, prehospital hydration is recommended for those with TCA characterized by a non-shockable rhythm before transport from the incident location.


Keywords

Traumatic cardiac arrest; Prehospital hydration; Initial cardiac rhythm


Cite and Share

Dae Kon Kim,Sang Do Shin,Young Sun Ro,Kyoung Jun Song,Joo Jeong,Ki Jeong Hong. Interaction effect between prehospital hydration and initial cardiac rhythm in traumatic out-of-hospital cardiac arrest: a nationwide observational study. Signa Vitae. 2024. 20(2);27-37.

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