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Original Research

Open Access

Effects of restrictive fluid resuscitation on the clinical efficacy of treating traumatic hemorrhagic shock combined with traumatic coagulopathy

  • Xinzhi Wang1
  • Li Pu2
  • Haibo Xu1
  • Lujie Niu1
  • Chen Yang3,*,

1Department of Trauma Surgery, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, China

2Department of Gynaecology and Obstetric, Suzhou Dushuhu Hospital Affiliated to Soochow University, 215000 Suzhou, Jiangsu, China

3Department of Emergency and Critical Medicine, The Second Affiliated Hospital of Soochow University, 215004 Suzhou, Jiangsu, China

DOI: 10.22514/sv.2024.007 Vol.20,Issue 1,January 2024 pp.120-126

Submitted: 07 November 2023 Accepted: 12 December 2023

Published: 08 January 2024

*Corresponding Author(s): Chen Yang E-mail: yc_dr06@163.com

Abstract

This study aims to assess the clinical efficacy of limited fluid resuscitation on traumatic hemorrhagic shock combined with traumatic coagulopathy. A cohort of 120 patients with traumatic hemorrhagic shock complicated with traumatic coagulopathy at admission were divided into two groups based on their emergency fluid resuscitation: the study group (received restrictive fluid resuscitation) and the control group (received conventional fluid resuscitation). Then, the incidence of complications, coagulation parameters, blood gas parameters and electrolyte parameters between the two groups were compared. The incidence of complications in the study group was 6.67%, which was significantly lower than the 20.00% observed in the control group (p < 0.05). Before resuscitation, there was no significant difference in coagulation parameters, blood gas parameters and electrolyte parameters between the two groups (p > 0.05), and in both groups, before and after resuscitation, the coagulation parameters after resuscitation were higher than those before resuscitation, blood gas parameters were lower than those before resuscitation, Mg2+, Cl and Na+ levels were higher than those before resuscitation, K+ was lower than that before resuscitation, and the difference had statistical significance (p < 0.05). After resuscitation, the coagulation parameters in the study group were significantly lower than those in the control group, the BL (Blood Lactic Acid) and PaCO2 (partial pressure of carbon dioxide in arterial blood) levels in the study group were lower than those in the control group, the BE (base excess) and PaO2 levels were higher than those in the control group, and the differences were statistically significant (p < 0.05). However, after resuscitation, we found no significant difference in electrolyte parameters between both groups (p > 0.05). Restrictive fluid resuscitation was found to significantly enhance coagulation and blood gas function, stabilize water and electrolyte balance and reduce complications in traumatic hemorrhagic shock patients complicated with traumatic coagulopathy. These findings hold substantial clinical significance and merit further exploration.


Keywords

Restrictive fluid resuscitation; Traumatic hemorrhagic shock; Traumatic coagulation; Clinical efficacy


Cite and Share

Xinzhi Wang,Li Pu,Haibo Xu,Lujie Niu,Chen Yang. Effects of restrictive fluid resuscitation on the clinical efficacy of treating traumatic hemorrhagic shock combined with traumatic coagulopathy. Signa Vitae. 2024. 20(1);120-126.

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