Title
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DOI
Article Type
Special Issue
Volume
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Effects of anesthesia and other perioperative factors on immune function: a narrative review
1Department of Anesthesiology and Perioperative Medicine, the First Affiliated Hospital of Nanjing Medical University, 210029 Nanjing, Jiangsu, China
2Department of Anesthesiology, the Affiliated Hospital of Xuzhou Medical University, 221002 Xuzhou, Jiangsu, China
DOI: 10.22514/sv.2024.105 Vol.20,Issue 9,September 2024 pp.1-15
Submitted: 01 January 2024 Accepted: 08 May 2024
Published: 08 September 2024
*Corresponding Author(s): Xiongxiong Pan E-mail: xiongxiong@njmu.edu.cn
† These authors contributed equally.
This study investigates the impact of perioperative factors on patients’ immune functions including physiological condition, surgical strategy, anesthesia methodology, intraoperative usage of anesthetics, blood transfusion, intraoperative body temperature, and inspired oxygen concentration. Results demonstrate that the individual perioperative factors have varying degree of impact, while their combined effect may cause changes in patients’ immune function. The study outcomes suggest that patient’s immune function must be assessed prior to the surgery based on individual characteristics. The surgical and anesthetic methods are accordingly selected. During the surgery, prudent usage and monitoring of factors like anesthesia techniques, anesthetics, inhaled oxygen concentration, blood transfusion, and patient’s body temperature are vital for minimizing the immune system disruptions. These findings practically guide regarding the optimization of perioperative care strategies and mitigation of immunosuppression risks.
Immune function; Perioperative factors; Anesthesia
Yining Chen,Junwei Kang,Yulang Wang,Xiongxiong Pan. Effects of anesthesia and other perioperative factors on immune function: a narrative review. Signa Vitae. 2024. 20(9);1-15.
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