Rh-positive blood type is associated with improved in-hospital mortality in patients with surgically treated acute type A aortic dissection

Background: Acute type A aortic dissection (ATAAD) is a severe cardiovascular emergency with high mortality. Shock, pericardial tamponade, malperfusion of coronary or peripheral arteries, and stroke are important predictive factors for in-hospital mortality in the setting of ATAAD. In this study, we aimed to evaluate the distribution of ABO blood groups and their effects on in-hospital mortality in ATAAD patients. Methods: The retrospective study included demographic and clinical data of 204 (surviving group: 154, non-surviving group: 50) patients diagnosed with ATAAD were collected from January 2013 to March 2016. The association between in-hospital mortality of ATAAD patients and ABO blood groups was analyzed using Binary logistic regression analysis. p value of < 0.05 was considered statistically significant. Results: There was a significant difference in terms of height, weight, cigarette smoking, hypertension, diabetes, ABO and Rh blood groups, systolic blood pressure, diastolic blood pressure (DBP), heart rate (HR), creatinine, glucose, white blood cells and fresh frozen plasma (FFP) transfusion between the surviving and non-surviving groups. Hight, Rh blood group, DBP, HR and admission blood glucose were independent predictors of in-hospital mortality. Conclusions: Our results show that Rh-positive blood type is an independent predictor of improved in-hospital mortality in patients with surgically treated acute type A aortic dissection. However, further studies involving large samples are needed to confirm the existence and strength of this relationship.

ABO blood groups; In-hospital mortality; Acute type A aortic dissection

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