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Epstein–Barr virus-associated focal cerebral arteriopathy in a child with stroke: a case report

  • Zih-Yang Lin1
  • Cheng-Chieh Huang1,2
  • Wen-Liang Chen2
  • Cheng Hsu Chen1,2
  • Chu-Chung Chou1,3
  • Yan-Ren Lin1,3,4,*,

1Department of Emergency and Critical Care Medicine, Changhua Christian Hospital, 500 Changhua, Taiwan

2Department of Biological Science and Technology, National Yang Ming Chiao Tung University, 300 Hsinchu, Taiwan

3School of Medicine, Chung Shan Medical University, 402 Taichung, Taiwan

4Department of Post Baccalaureate Medicine, College of Medicine, National Chung Hsing University, 402 Taichung, Taiwan

DOI: 10.22514/sv.2025.119 Vol.21,Issue 8,August 2025 pp.98-102

Submitted: 03 December 2024 Accepted: 31 March 2025

Published: 08 August 2025

*Corresponding Author(s): Yan-Ren Lin E-mail: 117214@cch.org.tw

Abstract

Background: Pediatric stroke is a rare but potentially life-threatening condition that often presents with nonspecific symptoms such as headache and vomiting, as well as focal neurological deficits or seizures in a minority of patients, making early diagnosis challenging. Case: A previously healthy child who presented with acute neurological deficits and was diagnosed with focal cerebral arteriopathy (FCA) on the basis of neuroimaging and serological findings. After treatment, she fully recovered without any neurological deficits. Conclusion: This case underscores the need for increased awareness of virus-associated arteriopathies in pediatric stroke patients, and emphasizes the importance of early recognition, neuroimaging, viral workup and treatment.


Keywords

Pediatric stroke; Emergency department; Focal cerebral arteriopathy (FCA); Epstein–Barr virus (EBV)


Cite and Share

Zih-Yang Lin,Cheng-Chieh Huang,Wen-Liang Chen,Cheng Hsu Chen,Chu-Chung Chou,Yan-Ren Lin. Epstein–Barr virus-associated focal cerebral arteriopathy in a child with stroke: a case report. Signa Vitae. 2025. 21(8);98-102.

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