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A year of impact: the best articles of 2024 in Signa Vitae
1Department of Cardiothoracic Anesthesia and ICU, Azienda Ospedaliero-Universitaria Pisana, 56100 Pisa, Italy
2Department of Emergency Medicine, Istanbul Training and Research Hospital, University of Health Sciences, 34098 Istanbul, Türkiye
3Faculty of Medicine, School of Health Sciences, Aristothele University of Thessaloniki, 54124 Thessaloniki, Greece
4Intensive Care Unit, Hospital General San Juan del Río, 76804 Querétaro, QT, México
5Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy
6School of Medicine, Vita-Salute San Raffaele University, 20132 Milan, Italy
7NEMA Research Group, Naples, FL 34108, USA
8Division of Infectious Diseases, Department of Medicine, McGill University, Montreal, QC H3A 0G4, Canada
9Instituto do Coração (InCor), Hospital das Clínicas Faculdade de Medicina da Universidade de São Paulo, 05403-000 São Paulo, SP, Brazil
10Instituto do Câncer (ICESP), Hospital das Clínicas Faculdade de Medicina da Universidade de São Paulo, 05403-000 São Paulo, SP, Brazil
11Regional Intensive Care Unit, Royal Victoria Hospital, BT12-6BA Belfast, Northern Ireland
DOI: 10.22514/sv.2025.139 Vol.21,Issue 10,October 2025 pp.1-5
Submitted: 18 August 2025 Accepted: 27 August 2025
Published: 08 October 2025
*Corresponding Author(s): Giovanni Landoni E-mail: landoni.giovanni@hsr.it
Sepsis; Cardioprotection; Neurocognition; Emergency
Fabio Guarracino,Ozgur Karcioglu,Eleni Moka,Orlando Rubén Pérez-Nieto,Matteo Borello,Giovanni Landoni,Joseph V. Pergolizzi,Todd C. Lee,Stephanie I. Rizk,Rob Mac Sweeney. A year of impact: the best articles of 2024 in Signa Vitae. Signa Vitae. 2025. 21(10);1-5.
[1] Yang YF, Wang XN, Huang JT, Lu XL, Xiao ZH. Extracorporeal membrane oxygenation for refractory septic shock in children. Signa Vitae. 2024; 20: 1–7.
[2] Tullo G, Covino M, Carbone L, Dico FL, Corsini G, Piccioni A, et al. Sepsis-induced coagulopathy (SIC) score is an independent predictor of mortality and overt-disseminated intravascular coagulation in emergency department patients with sepsis. Signa Vitae. 2024; 20: 33–43.
[3] Cotae AM, Mirea L, Cobilinschi C, Ungureanu R, Grinţescu IM. Early postoperative cognitive decline—are there any preventive strategies for surgical patients in the emergency setting? Signa Vitae. 2024; 20: 1–7.
[4] Möller Petrun A, Selinsek J, Mekis D. Neurological complication during pregnancy, delivery and puerperium requiring intensive therapy management. Signa Vitae. 2024; 20: 17–25.
[5] Greco M, Lombardi G, Konkayev A, Brusasco C, Lei C, Roasio A, et al. Remote ischemic preconditioning in non-cardiac surgery (PRINCE): a multinational, double blind, sham-controlled, randomized clinical trial. Signa Vitae. 2024; 20: 1–9.
[6] Crescenzi G, Torracca L, Pierri MD, Capestro F, Rosica C, Oliva FM, et al. Esmolol as a cardioprotective agent to reduce low cardiac output syndrome after cardiac surgery. Signa Vitae. 2024; 20: 69–77.
[7] Zamzami AM, Felimban AA, Khojah I, Bakhsh AA. Factors associated with prolonged emergency department length of stay in a resource-constrained setting. Signa Vitae. 2024; 20: 96–101.
[8] Shin Y, Cho KJ, Chang M, Youk H, Kim YJ, Park YJ, et al. The development and validation of a novel deep-learning algorithm to predict in-hospital cardiac arrest in ED-ICU (emergency department-based intensive care units): a single center retrospective cohort study. Signa Vitae. 2024; 20: 83–98.
[9] Serra M, Yuguero O. Clinical factors of patients who die in an emergency department: the significance of early clinical data, especially for the elderly. Signa Vitae. 2024; 20: 53–59.
[10] Greco M, Lombardi G, Brusasco C, Pieri M, Roasio A, Monaco F, et al. PRINCE Study Group. Effect of remote ischemic preconditioning on myocardial injury in noncardiac surgery: the PRINCE randomized clinical trial. Circulation. 2025. PMID: 40511609.
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