Article Data

  • Views 206
  • Dowloads 13

Original Research

Open Access

Tricuspid annular plane systolic excursion as a predictor of arterial hypotension induced by spinal anesthesia in cesarean section

  • Ferdi Gülaştı1,*,
  • Sevil Gülaştı2
  • Eray Çağlayan Çelik3
  • Sinem Sarı1,4

1Department of Anesthesiology and Reanimation, Faculty of Medicine, Adnan Menderes University, 09000 Aydin, Turkey

2Department of Cardiology, Faculty of Medicine, Adnan Menderes University, 09000 Aydin, Turkey

3Department of Anesthesiology and Reanimation, Aydin Maternity and Child Health Hospital, 09000 Aydin, Turkey

4Outcomes Research Consortium, Houston, TX 77001, USA

DOI: 10.22514/sv.2025.152

Submitted: 21 February 2025 Accepted: 31 March 2025

Online publish date: 10 October 2025

*Corresponding Author(s): Ferdi Gülaştı E-mail: ferdi.gulasti adu.edu.tr

Abstract

Background: Severe hypotension is a common complication following spinal anesthesia in cesarean section surgery due to the combined effects of spinal anesthesia and the gravid uterus compressing the inferior vena cava. This study aimed to evaluate the role of tricuspid annular plane systolic excursion (TAPSE) in predicting hypotension after spinal anesthesia in cesarean sections. Methods: This observational study included 60 pregnant women aged 20 to 35 years with an American Society of Anesthesiologists physical status of Class I scheduled for elective cesarean section under spinal anesthesia who provided informed consent. Preoperative TAPSE was assessed using transthoracic echocardiography. Intraoperative hemodynamic parameters were recorded, with non-invasive blood pressure measurements taken every two minutes. Results: TAPSE was an important predictor of hypotension following spinal anesthesia with the optimal cut-off value being ≤2.59 cm, with a sensitivity of 66.7% and a specificity of 73.9%. Conclusions: A TAPSE value of ≤2.59 cm, measured preoperatively using transthoracic echocardiography, was predictive of intraoperative hypotension in this study. Preoperative TAPSE assessment shows promise for predicting intraoperative hypotension, optimizing fasting durations, and guiding fluid management. To ensure the accuracy of these findings, additional studies are needed. Clinical Trial Registration: The study was registered with ClinicalTrials.gov as NCT05874687, Date: 25 May 2023.


Keywords

Tricuspid annular plane systolic excursion (TAPSE); Cesarean section; Spinal anesthesia; Hypotension; Volume


Cite and Share

Ferdi Gülaştı,Sevil Gülaştı,Eray Çağlayan Çelik,Sinem Sarı. Tricuspid annular plane systolic excursion as a predictor of arterial hypotension induced by spinal anesthesia in cesarean section. Signa Vitae. 2025.doi:10.22514/sv.2025.152.

References

[1] Kinsella SM, Lohmann G. Supine hypotensive syndrome. Obstetrics and Gynecology. 1994; 83: 774–788.

[2] Rees GA, Willis BA. Resuscitation in late pregnancy. Anesthesia. 1988; 43: 347–349.

[3] Kinsella SM. Lateral tilt for pregnant women: why 15-degree? Anaesthesia. 2003; 58: 835–836.

[4] Klöhr S, Roth R, Hofmann T, Rossaint R, Heesen M. Definitions of hypotension after spinal anesthesia for caesarean section: literature search and application to parturients. Acta Anaesthesiologica Scandinavica. 2010; 54: 909–921.

[5] Xu Z, Xu T, Zhao P, Ma R, Zhang M, Zheng J. Differential roles of the right and left toe perfusion index in predicting the incidence of postspinal hypotension during cesarean delivery. Anesthesia and Analgesia. 2017; 125: 1560–1566.

[6] Xue X, Lv X, Ma X, Zhou Y, Yu N, Yang Z. Prevention of spinal hypotension during cesarean section: a systematic review and bayesian network meta-analysis based on ephedrine, phenylephrine, and norepinephrine. The Journal of Obstetrics and Gynaecology Research. 2023; 49: 1651–1662.

[7] Gülaştı F, Kantarcı S. Investigating maternal effects of positions applied in patients preparing for caesarean section under spinal anesthesia: a prospective randomized clinical study. Turkiye Klinikleri Journal of Anesthesiology Reanimation. 2024; 22: 31–38.

[8] Silwal S, Subedi A, Bhattarai B, Ghimire A. Association between preoperative shock index and hypotension after spinal anesthesia for non-elective cesarean section: a prospective cohort study. BMC Anesthesiology. 2024; 24: 383.

[9] Fitzgerald JP, Fedoruk KA, Jadin SM, Carvalho B, Halpern SH. Prevention of hypotension after spinal anesthesia for caesarean section: a systematic review and network meta-analysis of randomized controlled trials. Anaesthesia. 2020; 75: 109–121.

[10] Kang H, Sung TY, Jee YS, Kwon W, Cho SA, Ahn S, et al. A comparison of norepinephrine versus phenylephrine to prevent hypotension after spinal anesthesia for cesarean section: systematic review and meta-analysis. Journal of Personalized Medicine. 2024; 14: 803.

[11] N P, Sinha M, Kumar M, Ramchandani S, Khetrapal M, Karoo K, et al. Role of internal jugular vein collapsibility index in predicting post-spinal hypotension in pregnant women undergoing cesarean section: a prospective observational study. Cureus. 2023; 15: e39389.

[12] Yao SF, Zhao YH, Zheng J, Qian JY, Zhang C, Xu Z, et al. The transverse diameter of right common femoral vein by ultrasound in the supine position for predicting post-spinal hypotension during cesarean delivery. BMC Anesthesiology. 2021; 21: 22.

[13] Juri T, Suehiro K, Yasuda S, Kimura A, Fujimoto Y, Mori T. Changes in the corrected carotid flow time can predict spinal anesthesia-induced hypotension in patients undergoing cesarean delivery: an observational study. Journal of Anesthesia. 2024; 38: 105–113.

[14] Harde MJ, Ranale PB, Fernandes S. Perfusion index to predict post spinal hypotension in lower segment caesarean section. Journal of Anaesthesiology, Clinical Pharmacology. 2024; 40: 37–42.

[15] Lee S, Kamdar F, Madlon-Kay R, Boyle A, Colvin-Adams M, Pritzker M, et al. Effects of the HeartMate II continuous-flow left ventricular assist device on right ventricular function. The Journal of Heart and Lung Transplantation. 2010; 29: 209–215.

[16] Zhao H, Kang Y, Pickle J, Wang J, Han Y. Tricuspid annular plane systolic excursion is dependent on right ventricular volume in addition to function. Echocardiography. 2019; 36: 1459–1466.

[17] Gülaşti F, Gülaşti S, Sari S. Tricuspid annular plane systolic excursion to predict arterial hypotension caused by general anesthesia induction. Minerva Anestesiologica. 2023; 89: 265–272.

[18] Kirchner J, Gerçek M, Omran H, Friedrichs KP, Rudolph F, Rossnagel T, et al. Predictive value of CT-based and AI-reconstructed 3D-TAPSE in patients undergoing transcatheter tricuspid valve repair. Frontiers in Cardiovascular Medicine. 2025; 11: 1463978.

[19] Singh Y, Anand RK, Gupta S, Chowdhury SR, Maitra S, Baidya DK, et al. Role of IVC collapsibility index to predict post spinal hypotension in pregnant women undergoing caesarean section. An observational trial. Saudi Journal of Anaesthesia. 2019; 13: 312–317.

[20] Nandini MG, Madhu S, Jyosthna Prabhat KS, Chaitra V, Monica K, Reshma M, et al. Peripheral perfusion index: a predictor of post-spinal hypotension in caesarean section. Cureus. 2022; 14: e25699.

[21] Hung KC, Liu CC, Huang YT, Wu JY, Chen JY, Ko CC, et al. Predictive efficacy of the perfusion index for hypotension following spinal anesthesia in parturient undergoing elective cesarean section: a systematic review and meta-analysis. Diagnostics. 2023; 13: 2584.


Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Chemical Abstracts Service Source Index The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications.

Index Copernicus The Index Copernicus International (ICI) Journals database’s is an international indexation database of scientific journals. It covered international scientific journals which divided into general information, contents of individual issues, detailed bibliography (references) sections for every publication, as well as full texts of publications in the form of attached files (optional). For now, there are more than 58,000 scientific journals registered at ICI.

Geneva Foundation for Medical Education and Research The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The overall objectives of the Foundation are to promote and develop health education and research programs.

Scopus: CiteScore 1.3 (2024) Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences.

Embase Embase (often styled EMBASE for Excerpta Medica dataBASE), produced by Elsevier, is a biomedical and pharmacological database of published literature designed to support information managers and pharmacovigilance in complying with the regulatory requirements of a licensed drug.

Submission Turnaround Time

Top