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Extracorporeal membrane oxygenation in nontraumatic critical care: new horizons in resuscitation

  • Feride Sinem Akgun1
  • Bilgen Ozkaya2
  • Göksu Afacan Ozturk3
  • Betul Akbuga Ozel4
  • Ozgur Karcioglu5,*,

1Department of Emergency Medicine, Okan University Faculty of Medicine, 34947 Istanbul, Türkiye

2Department of Emergency Medicine, Losante Children’s and Adult Hospital, 06830 Ankara, Türkiye

3Department of Emergency Medicine, Istanbul Aydin University, 34295 Istanbul, Türkiye

4Department of Emergency Medicine, Ankara Bilkent City Hospital, 06800 Ankara, Türkiye

5Department of Emergency Medicine, Istanbul Education and Research Hospital, 34098 Istanbul, Türkiye

DOI: 10.22514/sv.2025.157

Submitted: 31 May 2025 Accepted: 13 August 2025

Online publish date: 20 October 2025

*Corresponding Author(s): Ozgur Karcioglu E-mail: Ozgur.Karcioglu@saglik.gov.tr

Abstract

Extracorporeal membrane oxygenation (ECMO) transfers blood from a large vein into a machine, oxygenates it, and then reinfuses the oxygenated blood back to the patient through a large vascular catheter. Resuscitation procedures using ECMO are known as extracorporeal cardiopulmonary resuscitation or extracorporeal life support. On one hand, the procedure is suitable for selected patients with severe respiratory diseases, cardiogenic or septic shock, intoxications, thyrotoxicosis, trauma, or cardiac arrest. On the other hand, geriatric persons with multiple diseases, end-stage malignancies, those with cardiopulmonary diseases, or dementia are not candidates for extracorporeal cardiopulmonary resuscitation (ECPR). The potential indications for ECMO are still expanding, but well-designed, multicentric studies are needed to assess benefit and harms.


Keywords

Extracorporeal membrane oxygenation; Extracorporeal cardiopulmonary resuscitation; Extracorporeal life support; Resuscitation; Survival; Cardiac arrest


Cite and Share

Feride Sinem Akgun,Bilgen Ozkaya,Göksu Afacan Ozturk,Betul Akbuga Ozel,Ozgur Karcioglu. Extracorporeal membrane oxygenation in nontraumatic critical care: new horizons in resuscitation. Signa Vitae. 2025.doi:10.22514/sv.2025.157.

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