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Sphenopalatine Ganglion Block (SPG) for the treatment of migraine

  • Sofia Papantonaki1
  • Aikaterini Lappa1
  • Athanasia Dragatsiki2
  • Evaggelia Gavrilaki2

1Anaesthesiology Department, General Hospital of Agios Nikolaos, Lasithi, Crete, Greece

2Nursing Department, General Hospital of Agios Nikolaos, Lasithi, Crete, Greece

DOI: 10.22514/sv.2021.170 Vol.17,Issue S1,September 2021 pp.25-25

Submitted: 26 August 2021 Accepted: 06 September 2021

Published: 15 September 2021

*Corresponding Author(s): Sofia Papantonaki E-mail:


Aim: Migraine is the second most common form of headache after tension headache. Migraine affects 11% of the population, and is 3 times more common in women than in men. Studies have shown that migraine affects the functionality of patients at a rate of 53.7%. Aim of this study is to describe the effectiveness of SPG blockade in a female patient with chronic persistent migraine.

Methods & material: We used data from our clinic. The patient came to our clinic with severe migraine (VAS pain 10) for more than two years. Her history reports migraine worsening in the last two years (>15 episodes per month). The pain is localized unilaterally is high intensity and with pulsating character. She also refers nausea, vomiting and dizziness with pain. After the remission of acute pain the patient describes cognitive dysfunction, depression and weakness. Her medication was Paracetamol 1 gr every 6 hours, Sertraline 100 mg daily, Amitriptyline 25 mg daily and Rizatriptan10mg for crisis treatment. SPG blockage was suggested to her for treatment which she accepted. Lidocaine 2% 0.6 mL to each nostril administered via nasal catheter (TX 360).

Results: A total of 4 treatments were applied (1 every 30 days). At the end of the first treatment the patient reports pain relief after 15 minute VAS pain 6. The only side effect was tearing. She gradually reduced her medication. She only retain Rizatriptan. She was also start prophylactic treatment of migraine with Propranolol. At the end of the four treatment the patient reports VAS pain 0, without any episodes of acute pain and she return to her normal activity.

Conclusions: SPG blockage is a simply effective and painless method to treat chronic migraine, without any serious side effects.

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Sofia Papantonaki,Aikaterini Lappa,Athanasia Dragatsiki,Evaggelia Gavrilaki. Sphenopalatine Ganglion Block (SPG) for the treatment of migraine. Signa Vitae. 2021. 17(S1);25-25.


[1] Binfalah M, Alghawi E, Shosha E, Alhilly A, Bakhiet M. Sphenopalatine Ganglion Block for the Treatment of Acute Migraine Headache. Pain Research and Treatment. 2018; 2018: 2516953.

[2] Spector K, Sahai-Srivastava S. A new look at sphenopalatine ganglion blocks for chronic migraine. Practical Pain Management. 2017; 16:

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