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Original Research

Open Access Special Issue

Is early surgical intervention effective for traumatic severe cervical spinal cord injury? A retrospective study secondary publication

  • Koji Yamamoto1
  • Akinori Okuda1,2
  • Naoki Maegawa1,2
  • Hironobu Konishi1,2
  • Keita Miyazaki1
  • Yusuke Tada1
  • Yohei Kogeichi1
  • Keisuke Takano1
  • Hideki Asai1
  • Yasuyuki Kawai1
  • Yasuyuki Urisono1
  • Hideki Shigematsu2
  • Kenji Kawamura2
  • Hidetada Fukushima1
  • Yasuhito Tanaka2

1Department of Emergency and Critical Care Medicine, Nara Medical University, 634-8522 Kashihara, Nara, Japan

2Department of Orthopedic Surgery, Nara Medical University, 634-8522 Kashihara, Nara, Japan

DOI: 10.22514/sv.2021.256

Submitted: 28 September 2021 Accepted: 23 November 2021

Online publish date: 30 December 2021

(This article belongs to the Special Issue Spinal Cord Injury)

*Corresponding Author(s): Akinori Okuda E-mail: okuda74@icloud.com

Abstract

Although early surgery is known to be effective for the treatment of traumatic cervical spinal cord injury (CSCI), whether it is equally effective in severe CSCI cases remains undetermined. This study aimed to determine whether surgery within 24 h improves the neurological prognosis and reduces the complications associated with surgery for traumatic severe CSCI. The data of 42 patients with traumatic severe CSCI with American Spinal Injury Association Impairment Scale (AIS) grades A–B who underwent surgery between December 2007 and May 2018 were retrospectively reviewed. The participants were classified into early surgery (<24 h) and late surgery (>24 h) groups. Using the inverse probability of treatment weighting with propensity score adjustment for confounding factors, the AIS grades before and 1 month following surgical treatment, which were considered the primary outcomes, were compared. The secondary outcomes were the intensive care unit length of stay (ICU-LOS) and occurrence of respiratory complications and cardiac arrest. In the early surgery group (n = 32, 76%), the average time to surgery was 10.25 h (4–23 h). The inverse probability of treatment weighting analysis indicated significant differences in the neurological improvement according to the AIS grade at 1 month following surgery (odds ratio [OR]: 17.1, 95% confidence interval [Cl]: 1.9–156.7, p = 0.012), the ICU-LOS >7 days (OR: 0.14, 95% Cl: 0.02–0.90, p = 0.04), and the occurrence of respiratory complications (OR: 0.08, 95% Cl: 0.01–0.73, p = 0.03) and cardiac arrest (OR: 0.13, 95% Cl: 0.02–0.85, p = 0.03). Early surgery (within 24 h) for traumatic severe CSCI may improve the neurological prognosis and prevent a long ICU-LOS and postoperative complications.


Keywords

Cervical vertebrae; Spinal cord injury; Early surgery; Early intervention; American Spinal Injury Association Impairment Scale; Retrospective studies


Cite and Share

Koji Yamamoto,Akinori Okuda,Naoki Maegawa,Hironobu Konishi,Keita Miyazaki,Yusuke Tada,Yohei Kogeichi,Keisuke Takano,Hideki Asai,Yasuyuki Kawai,Yasuyuki Urisono,Hideki Shigematsu,Kenji Kawamura,Hidetada Fukushima,Yasuhito Tanaka. Is early surgical intervention effective for traumatic severe cervical spinal cord injury? A retrospective study secondary publication. Signa Vitae. 2022.doi:10.22514/sv.2021.256.

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