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Special Issue Title:

Acute Native Joint Septic Arthritis an Update

Deadline for manuscript submissions: 31 March 2022

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Special Issue Editor

  • Guest Editor

    Dr. Sachin PatilE-MailWebsite

    PGY 6 Critical Care Fellow, University of Missouri Hospital and Clinic, 1 Hospital Drive, Columbia, MO 65212

    Interests: Bacterial, Fungal and Mycobacterial Infections, Critical Care, Pulmonary Infections

Special Issue Information

Acute infection of single or multiple joint spaces is an emergency awaiting immediate intervention. Etiologic agents include bacterial, viral, fungal, and parasites. Septic arthritis occurs due to bacteremia, adjoining infectious foci, or traumatic inoculation. The incidence is increasing due to the opioid epidemic since 2010. Monoarticular involvement is frequent. The knee is the most common joint affected. Gram-positive agents account for the majority of the infections. Viral causes are sporadic, seen in outbreaks or endemic areas, causing symmetric polyarticular arthritis. It is prudent to identify certain demographic risk factors with an increased risk of infection. Acute Noninfectious inflammatory conditions such as gout, rheumatoid, or lupus arthritis should be in the differential. Labs such as complete blood count, inflammatory markers, and synovial fluid analysis with culture help identify the organism. It is essential to image the joint to determine the extent of infection and confirm the diagnosis. An arthrocentesis is a must before antibiotic administration to increase synovial fluid culture yield. An empirical regimen covers both gram-positive and gram-negative bacilli with the addition of antifungal agents in select high-risk patients. An extensive infection will need surgical intervention for a cure. Antimicrobials are de-escalated based on the synovial fluid culture results. The ideal duration of antibiotics is around four weeks and can be transitioned from intravenous to oral agents once the patient is clinically stable.


Infection, Septic arthritis, Bacteria, Joint, Arthrocentesis

Manuscript Submission Information

Manuscripts should be submitted online by submit system. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Original articles, case reports or comprehensive reviews are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Signa Viate is an international peer-reviewed open access journal published by MRE Press. As of January 2021, Signa Vitae will change to a bimonthly journal. Please visit the Instructions for Authors page before submitting a manuscript.The Article Processing Charge (APC) for publication in this open access journal is $1200. We normally offer a discount greater than 30% to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.

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Plan Papers (4 papers)

Acute Pseudomonas Septic Arthritis

Sachin M. Patil, et al.

Acute Group B Strep Septic Arthritis

Sachin M. Patil, et al.

Acute Staph Aureus Septic Arthritis

Sachin M. Patil, et al.

Acute Staph Aureus Bacteremia

Sachin M. Patil, et al.

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