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Special Issue Title:

Anaesthesia in Paediatrics: Take Good Care of the Children

Deadline for manuscript submissions: 25 August 2021

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Special Issue Editor

  • Guest Editor

    Prof. Dr. Tom Giedsing HansenE-MailWebsite

    Department of Anesthesia & Intensive Care – Pediatric Section, Odense University Hospital, Odense, Denmark

    Interests: Pediatric emergency medicine, Neonatology, Pediatrics, Pulmonary ventilation, Medical education, General anesthesia

Special Issue Information

Dear Colleagues,

Laboratory research over the past 2 decades has raised concerns about the effects of anaesthesia and surgery in the developing brain. There is a controversy if this neuromorbidity may result from the potentially toxic effects of anaesthetic drugs on the central nervous system or may arise from an inappropriate conduct of anaesthesia and from surgery.

A recent large scale European human observational study (the APRICOT study) demonstrated that the incidence of severe critical events associated with anaesthesia in children is higher than previously believed with startling differences among the European countries (20 to 30 times variation). Obviously many factors are important here, but there was statistical evidence that experienced paediatric anaesthesiologists and teams with a higher volume of paediatric patients had significantly fewer severe critical events. Further, the results suggest that children less than 3 years of age should be managed by more experienced teams with specific paediatric training and support.

The Safetots initiative was established to emphasize the role of the conduct of anaesthesia to prevent harm in the perioperative period and to promote safe and high quality clinical care. This initiative a priori considers that the quality of anaesthesia management and other well-known known risk factors of perioperative care have a far more important impact on outcomes following anaesthesia and surgery.

The Safetots initiative acknowledges a number of issues that are important:

1. Smaller, younger and sicker children may have more problems with anaesthesia because there is a smaller safety margin around normal and changes from normal can happen much more quickly. This is especially so in emergency or urgent cases.

2. Children who have complex surgery or longer procedures may also be more at risk of problems.

3. The rights of the child according to the UN, i.e. the rights of a child to the enjoyment of the highest attainable standard of health care the 5 Ws (who, what, where, when and how).

4. The importance of maintaining physiological homeostasis for the safe conduct of anaesthesia in children.

5. The importance of both continuous individual and institutional quality improvement to improve paediatric anaesthesia.

6. Everybody involved in paediatric anaesthesia needs a lot of training and experience to care for children to keep them safe during and after anesthesia and surgery.


Paediatric anaesthesia, Anaesthesia, Surgery, Potentially toxic effects, Children, Health care, Physiological homeostasis, Training and experience

Manuscript Submission Information

Manuscripts should be submitted online by submit system. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Original articles, case reports or comprehensive reviews are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Signa Viate is an international peer-reviewed open access journal published by MRE Press. As of January 2021, Signa Vitae will change to a bimonthly journal. Please visit the Instructions for Authors page before submitting a manuscript.The Article Processing Charge (APC) for publication in this open access journal is $1200. We normally offer a discount greater than 30% to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.

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Published Papers (7 papers)

Open Access Special Issue

Comparison of the effects of desflurane and sevoflurane on emergence characteristics in pediatric patients premedicated with ketamine

Hyojoong Kim,Ki Hwa Lee,Yei Heum Park,Soo Jung Lee,Se Hun Kim,Sang Eun Lee,Yong Han Kim,Yu Kyung Jeon

DOI: 10.22514/sv.2021.045

(This article belongs to the Special Issue Anaesthesia in Paediatrics: Take Good Care of the Children)

Abstract ( 2840 ) PDF (726.75 kB) ( 236 ) Full Text

Open Access Special Issue

Postoperative emergence delirium in children: a narrative review of recent publications

Oda Grung Grotmol,Narththahi Nesarajah,Tom Giedsing Hansen

DOI: 10.22514/sv.2021.057

(This article belongs to the Special Issue Anaesthesia in Paediatrics: Take Good Care of the Children)

Abstract ( 3400 ) PDF (840.29 kB) ( 445 ) Full Text

Open Access Special Issue

Children undergoing anaesthesia: what are the rights of the child?

Kristian Noerholm Jensen,Tom Giedsing Hansen

DOI: 10.22514/sv.2021.059

(This article belongs to the Special Issue Anaesthesia in Paediatrics: Take Good Care of the Children)

Abstract ( 2632 ) PDF (221.96 kB) ( 260 ) Full Text

Open Access Special Issue

Why complex surgeries in children are associated with poorer outcomes

Mathias Johansen,Vincent Collard,Thomas Engelhardt

DOI: 10.22514/sv.2021.060

(This article belongs to the Special Issue Anaesthesia in Paediatrics: Take Good Care of the Children)

Abstract ( 2503 ) PDF (209.6 kB) ( 205 ) Full Text

Open Access Special Issue

From little adults to pediatric patients: quality improvement in pediatric anesthesia

Nicola G. Clausen,Tom Giedsing Hansen

DOI: 10.22514/sv.2021.088

(This article belongs to the Special Issue Anaesthesia in Paediatrics: Take Good Care of the Children)

Abstract ( 2938 ) PDF (163.86 kB) ( 334 ) Full Text

Open Access Special Issue

Fasting in pediatric anesthesia: the art of making simple things complex

Nadia Veigaard,Nicole Brahe,Tom G. Hansen,Nicola G. Clausen

DOI: 10.22514/sv.2021.139

(This article belongs to the Special Issue Anaesthesia in Paediatrics: Take Good Care of the Children)

Abstract ( 3151 ) PDF (458.34 kB) ( 414 ) Full Text

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