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Special Issue Title:

Opioid Free Analgesia: new concept, new trends

Deadline for manuscript submissions: 01 April 2022

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Special Issue Editor

  • Guest Editor

    Dr. Mohamed Adel AboelelaE-MailWebsite

    MD, Consultant of anesthesia and SICU, Mansoura university hospitals, Egypt. Lecturer of anesthesia and SICU, Faculty of medicine, Mansoura university, Egypt.

    Interests: Neuroanesthesia, Liver transplantation anesthesia

Special Issue Information

Analgesia is a one of the three corner stones in anesthesia field. Perioperative pain or lacking of adequate analgesia affects hemodynamics, recovery, prognosis and overall patient's experience to surgical practice. For long times, opioids took the upper hand in such use, but it isn't free of side effects and complications which may burden patient's safety. Using non opioid drugs, regional blocks gained popularity in recent decades with promising results. Also, trends of preemptive analgesia proved efficacy. Opioid free anesthesia (OFA) explored in many trials with superior results. Drugs like ketamine, lidocaine, dexmedetomedine, dexamethasone used as co-analgesics outside its original indications.

All of these drugs or techniques have systemic effects based on used drug, dose, route of administration, patient's age, gender and associated co-morbidities. Nevertheless, techniques of regional block considered invasive and may be associated with hazards even with ultrasound guidance. Placing catheters for epidural use or regional plane block may carry risk of infection or need special precautions in patients receiving anti-coagulants.

SO, the new concept now targeting to minimize drug use, and interventions. The question is, can we use operative, or anesthetic, or ventilation techniques to improve patients experience toward pain? Can we use simple drugs like vitamins to minimize the need to systemic analgesic drug? Can we omit opioids use in perioperative analgesia? This is considered our challenge in future days, and in this special issue.

We welcome articles, trials, commentaries exploring new trends and techniques in analgesia practice.


Analgesia, Pain, Opioids, OFA, Regional block

Manuscript Submission Information

Manuscripts should be submitted online by submit system. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Original articles, case reports or comprehensive reviews are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website. Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Signa Viate is an international peer-reviewed open access journal published by MRE Press. As of January 2021, Signa Vitae will change to a bimonthly journal. Please visit the Instructions for Authors page before submitting a manuscript.The Article Processing Charge (APC) for publication in this open access journal is $1200. We normally offer a discount greater than 30% to all contributors invited by the Editor-in-Chief, Guest Editor (GE) and Editorial board member. Submitted papers should be well formatted and use good English.

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Published Papers (5 papers)

Open Access Special Issue

Comparison of dexmedetomidine and lipophilic opioids as adjuvants to local anesthetics for epidural labor analgesia: a meta-analysis of randomized controlled trials

Shi-ke Yang,Min Liu,Jie Chen,Yuan-yuan Yang,Fang-zheng Zhuan,Wen-qun Sun,De-zhi Mao

DOI: 10.22514/sv.2021.242

(This article belongs to the Special Issue Opioid Free Analgesia: new concept, new trends)

Abstract ( 2669 ) PDF (6.93 MB) ( 317 ) Full Text

Open Access Special Issue

Dexmedetomidine versus fentanyl on stress response and pain control in adult patients undergoing laparoscopic surgery

Marian Greiss,Bassem Boulos Ghobrial,Waleed Mohamed Abd Elmageed,Dalia Mahmoud Elfawy,Raham Hasan Mostafa

DOI: 10.22514/sv.2022.007

(This article belongs to the Special Issue Opioid Free Analgesia: new concept, new trends)

Abstract ( 3324 ) PDF (2.49 MB) ( 350 ) Full Text

Open Access Special Issue

The quality and continuity of systemic postoperative analgesia: a single center two-stage follow-up study

Jurate Gudaityte,Laura Jazokaite,Brigita Saduikyte,Danguole Ceslava Rugyte

DOI: 10.22514/sv.2022.068

(This article belongs to the Special Issue Opioid Free Analgesia: new concept, new trends)

Abstract ( 2342 ) PDF (1,019.69 kB) ( 178 ) Full Text

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