Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

Signa Vitae (SV) is a peer-reviewed, open-access journal that aims to be an unbiased and permanent forum for the fields of emergency medicine, intensive care medicine, anesthesia and pain medicine. It focuses on the latest research advances in these fields, including Disease prevention, diagnose, treatment and prognosis, Disease etiology, pathophysiology, and molecular mechanisms, Health care, Medical personnel health, Facilities and equipment, Teaching and training, Organization and management, Information and techniques, Drug application, etc. As a tool for easier and more effective experiences and science sharing, SV aims to provide professionals dedicated to all these relevant fields with cutting-edge techniques and information.



Call for papers: Advances in the Diagnosis and Management of Sepsis and Septic Shock
Acute Trauma: Immediate Interventions, Long-Term Impacts, Advancements, and Medico-legal Evaluation

Articles

Open Access

QTc changes in elderly patients: a comparison of spinal and general anesthesia

Cezmi Yalim,Sinan Uzman,Serhat Kavak,Mehmet Halici,Onur Coban

DOI: 10.22514/sv.2025.079

Abstract ( 294 ) PDF (2.64 MB) ( 152 ) Full Text

Open Access

Pain management in acute apical abscesses with valacyclovir monotherapy after emergency chamber opening: a prospective randomized clinical study

Nayab Fatima,Muhammad Adeel Ahmed,Yumna Shaheen Ali,Fazal-ur-Rehman Qazi,Hasan Afaq Zaidi,Ziaullah Choudhry,Rizwan Jouhar

DOI: 10.22514/sv.2025.081

Abstract ( 270 ) PDF (669.65 kB) ( 125 ) Full Text

Open Access

Effects of bupivacaine wound infiltration and transversus abdominus plane block on healing and postoperative adhesion of colonic anastomosis in rats

Sevgi Kesici,Yahya Kaan Karatepe,Sibel Oba,Mahmut Salih Genç,Ahmet Furkan Mazlum,Kubra Bozali,Mehmet Guray Duman,Tamer İmamoglu,Eray Metin Guler,Ugur Kesici

DOI: 10.22514/sv.2025.029

Abstract ( 1146 ) PDF (200.61 kB) ( 200 ) Full Text

Open Access

Variations in oxygen reserve index in different fresh gas flow rates

Fatih Sahin,Yakup Uzun,Burak Kaya,Havva Kocayigit,Ali Fuat Erdem

DOI: 10.22514/sv.2025.084

Abstract ( 248 ) PDF (3.09 MB) ( 118 ) Full Text

Open Access

TRIM21 alleviates acute pancreatitis cell injury and promotes efferocytosis by targeting CD47

Taizhe Zhang,Jie Du,Sandang Li,Zhenjie Wang,Chuanming Zheng

DOI: 10.22514/sv.2025.086

Abstract ( 250 ) PDF (9.12 MB) ( 152 ) Full Text

Open Access

Etiology of pediatric forensic cases: comparison of emergency department admissions in childhood and adolescence

Nuray Aslan,Fatih Guneysu,Necip Gokhan Guner,Ensar Durmuş,Sacit Akdeniz,Yusuf Yurumez,Murat Özsaraç,Mehmet Alperen Biçer

DOI: 10.22514/sv.2025.087

Abstract ( 283 ) PDF (654.13 kB) ( 138 ) Full Text

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Published Ahead of Print

Open Access

Acute normovolemic hemodilution in cardiac surgery and the power of global collaboration in advancing research

Fabio Guarracino,Matteo Aldo Bonizzoni,Rosario Losiggio,Gianluca Paternoster

Online publish date: 26 May 2025

DOI: 10.22514/sv.2025.076

Abstract ( 738 ) PDF (312.19 kB) ( 191 ) Full Text

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Call for Papers!
Early postoperative cognitive decline—are there any preventive strategies for surgical patients in the emergency setting?
Development of a real-time monitoring and detection indoor air quality system for intensive care unit and emergency department

Special Issues

Special issue title:

Advances in Emergency Cardiac Care

Keywords: Ischemic Heart Disease; Heart Failure; Arrhythmia; Defibrillation; PCI; Telemedicine; Resuscitation

Editor: Prof. Dr. Ozgur Karcioglu, MD, FEMAT,Assoc. Prof. Dr. Canan Akman, MD

Submission deadline: 01 March 2026

Special issue title:

Acute Trauma: Immediate Interventions, Long-Term Impacts, Advancements, and Medico-legal Evaluation

Keywords: EMS; Trauma Management; Healthcare System Preparedness; Medico-Legal Evaluation

Editor: Prof. Dr. Giuseppe Basile, MD,Dr. Luca Bianco Prevot, MD,Dr. Vittorio Bolcato, MD

Submission deadline: 31 January 2026

Special issue title:

Advances in the Diagnosis and Management of Sepsis and Septic Shock

Keywords: Diagnosis; Management; Sepsis; Septic Shock; Lactate Hypotension; Vasopressors

Editor: Prof. Dr. Ozgur Karcioglu, MD,Assoc. Prof. Dr. Feride Sinem AKGUN, MD,Assist. Prof. Dr. Betul AKBUGA OZEL, MD

Submission deadline: 01 May 2026

Special issue title:

Optimization of Cardiovascular Dynamics in Critical Care Medicine and Anesthesiology

Keywords: Critical Care Medicine; Anesthesiology; Cardiovascular Dynamics; Hemodynamics

Editor: Prof. Dr. Athanasios Chalkias, MD, MSc, PhD, FESC, FAcadTM, FCP, FESAIC,Dr. Paraskevi Tselioti, MD, PhD

Submission deadline: 31 December 2025

Special issue title:

Critical Interventions: Enhancing Emergency Medical Services through Interdisciplinary Research

Keywords: Emergency Medical Services; Interdisciplinary Research in EMS; Pre-hospital Care Technologies; Crisis Management in Healthcare; Psychological Aspects of EMS; Public Health and Emergency Services

Editor: Prof. Dr. Krzysztof Goniewicz, PhD,Prof. Dr. Ahmed M. Al-Wathinani, PhD

Submission deadline: 28 February 2025

Special issue title:

Advances in Obstetric Anaesthesia

Keywords: Obstetric Anaesthesia; Epidural Analgesia; Remifentanil-PCA; Labour and Delivery Outcomes; Quality Control in Perinatology and Obstetric Anaesthesia; ROTEM; Obstetric Haemorrhage; Preeclampsia

Editor: Prof. Tatjana Stopar Pintarič, MD, PhD, DEAA

Submission deadline: 31 December 2023

Special issue title:

Cardiothoracic anaesthesia and intensive care: current challenges and novelties

Keywords: cardiac anaesthesia, thoracic anaesthesia, intensive care, education, innovation, perioperative medicine, healthcare, outcomes, challenges

Editor: Dr. Marko Zdravkovic, MD, PhD

Submission deadline: 30 November 2022

Special issue title:

Selected papers from Korean Society of Emergency Medicine (KSEM) in 2021-2022

Keywords: Emergency medicine

Editor: Kyungwon Lee, MD, PhD,Young Duck Cho, MD, PhD

Submission deadline: 31 December 2022

Special issue title:

Medical Simulation - success in education, future of science

Keywords: medical simulation, emergency medicine, medical education

Editor: Tomasz Kłosiewicz, MD, MSc,Mateusz Puślecki, PhD

Submission deadline: 31 December 2022

Special issue title:

21st Panhellenic Congress on Regional Anaesthesia, Pain Management and Palliative Care

Keywords: Regional Anaesthesia, Pain Management, Palliative Care, PARH.SY.A., ESRA HELLAS, the A’ Anaesthesiology Department, Faculty of Medicine, University of Athens

Editor: Dr. Ioanna Siafaka, MD, PhD,Dr. Maria Kokolaki, MD, PhD,Dr. Athina Vadalouca, MD, PhD, FIPP,Dr. Evmorfia Stavropoulou, MD, PhD, EDRA,Dr. Eleni Moka, MD, PhD, MSc, EDRA

Submission deadline: 27 May 2022

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To Be a Reviewer

If you would like to review a manuscript for Signa Vitae journal, please click “Review for SV” below to register at our submission website or log in our Online Peer Review system. Your name, contact details, and expertise will be automatically added to our database of reviewers.

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Join Editorial Board

You are welcome to join our editorial board. Our journal produces and issues editorial board certificates for editorial board members, and the journal website will display the names and personal websites of editorial board members to help enhance their scientific influence. Members of the editorial committee are entitled to 1 free publication (editorial member’s or recommended paper) per year, and other articles over 2 can enjoy 30% discount of publishing fee.

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Editor-in-Chief

Prof. Giovanni Landoni, MD

Prof Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals.