Signa Vitae

Print ISSN: 1334-5605 | Online ISSN: 1845-206X

Official journal of the International Women in Intensive and critical care Network (iWIN, https://www.iwinideal.com/home/)

Signa Vitae (SV) is a peer-reviewed, open-access journal that aims to be an unbiased and permanent forum for the fields of emergency medicine, intensive care medicine, anesthesia and pain medicine. It focuses on the latest research advances in these fields, including Disease prevention, diagnose, treatment and prognosis, Disease etiology, pathophysiology, and molecular mechanisms, Health care, Medical personnel health, Facilities and equipment, Teaching and training, Organization and management, Information and techniques, Drug application, etc. As a tool for easier and more effective experiences and science sharing, SV aims to provide professionals dedicated to all these relevant fields with cutting-edge techniques and information.



Articles

Open Access

Too soon to deflate? Rethinking IABP in the era of Altshock-2

Maks Mihalj,Charles Wanna,Sriram Nathan,Harish Devineni,Alessandro Belletti,Anna Mara Scandroglio,Igor D. Gregoric,Angelo Nascimbene,Biswajit Kar

DOI: 10.22514/sv.2025.189

Abstract ( 80 ) PDF (152.12 kB) ( 14 ) Full Text

Open Access

Antifibrotic therapy in patients with acute lung injury: a systematic review and meta-analysis

Nora Di Tomasso,Valentina Ajello,Gianluca Paternoster,Daniele Orso,Carolina Soledad Romero Garcia,Laura Pasin,Filippo D’Amico,Luigi Beretta,Alberto Zangrillo,Giacomo Monti,PIONEER study group

DOI: 10.22514/sv.2025.163

Abstract ( 833 ) PDF (2.65 MB) ( 40 ) Full Text

Open Access

Aspartate aminotransferase to platelet ratio index as a predictor of mortality in traumatic brain injury

Ching-Ya Huang,Ching-Hua Tsai,Wei-Ti Su,Shiun-Yuan Hsu,Ching-Hua Hsieh

DOI: 10.22514/sv.2025.155

Abstract ( 536 ) PDF (1.46 MB) ( 18 ) Full Text

Open Access

Evaluating sarcopenia in emergency department triage: implications for hospitalization and critical care

Li-Chin Chen,Chip-Jin Ng,Chin-Yen Han,Cheng-Yu Chien,Shu-Yu Kuo

DOI: 10.22514/sv.2025.162

Abstract ( 671 ) PDF (4.91 MB) ( 27 ) Full Text

Open Access

Characteristics and outcomes of patients with solid tumors admitted to the intensive care unit in Saudi Arabia

Abdullah M. Alhammad,Saleh S. Alzahrani,Lama T. Almutairi,Mohammad H. Aljawadi,Reema H. Alfehaid,Alaa Z. Alhajjari,Nora A. Alkhudair,Rakan M. Alqahtani,Fadi S. Aljamaan,Khalid A. Al Sulaiman,Rashid K. Alballaa,Mohammad A. Alghamdi,Mohammed I. Alarifi

DOI: 10.22514/sv.2025.158

Abstract ( 674 ) PDF (341.49 kB) ( 19 ) Full Text

Open Access

A modified risk model for upper gastrointestinal bleeding: comparative evaluation of the H3B2A1 score

Meliha Fındık,Muhammet Çakas,Ahmet Buğra Önler,Murat Başcı,Selman Gümüş,Ramazan Kıyak

DOI: 10.22514/sv.2025.180

Abstract ( 505 ) PDF (1.93 MB) ( 16 ) Full Text

Open Access

Can CALLY score predict mortality and ICU stay in elderly patients with sepsis?

Ayşe Begum Çakır,Gorkem Alper Solakoglu,Kerim Erim,Behcet Al

DOI: 10.22514/sv.2025.166

Abstract ( 683 ) PDF (2.47 MB) ( 26 ) Full Text

Open Access

Early predictors of acute kidney injury after Cardiac Surgery

Zinet Asuman Arslan Onuk,Gökhan Ozerdem,Sibel Kulaksızoglu,Birkan Akbulut,Fatih Metinyurt,Aysen Baysan,Levent Donmez

DOI: 10.22514/sv.2025.153

Abstract ( 889 ) PDF (4.31 MB) ( 26 ) Full Text

Open Access

Correlation of frontal QRS-T angle with mortality in ischemic stroke patients: a multicenter study

Murat Genç,Didem Çankaya Gökdere,Adil Emre Gezer,Melih Çamcı,Bensu Bulut,Medine Akkan Öz,Ramiz Yazıcı,Huseyin Mutlu,Zekeriya Uykan

DOI: 10.22514/sv.2025.194

Abstract ( 74 ) PDF (6.16 MB) ( 15 ) Full Text

Published Ahead of Print

Open Access

Analysis of medical evacuation following the Tünektepe cable car accident in Turkey in 2024

Mustafa Keşaplı,Adeviyye Aksoy,Deniz Kılıç,Mehmet Fatih Gülşen

Online publish date: 03 December 2025

DOI: 10.22514/sv.2025.187

Abstract ( 259 ) PDF (3.22 MB) ( 11 ) Full Text

Open Access

Hypermagnesemia and mortality in COPD patients

Ceren Önal,Kazım Koray Özgül,Ayşe Kösem,Yalçın Şenol,Gülten Arslan

Online publish date: 03 December 2025

DOI: 10.22514/sv.2025.188

Abstract ( 221 ) PDF (589.38 kB) ( 17 ) Full Text

Open Access

Non-invasive respiratory support for postoperative acute hypoxemic respiratory failure: a narrative review

Francesco Coppolino,Pasquale Sansone,Gianluigi Cosenza,Leonardo Maria Bottazzo,Simona Brunetti,Sara De Sarno,Maurizio Del Prete,Maria Beatrice Passavanti,Marco Fiore,Clelia Esposito,Maria Caterina Pace,Vincenzo Pota

Online publish date: 28 November 2025

DOI: 10.22514/sv.2025.186

Abstract ( 380 ) PDF (308.46 kB) ( 12 ) Full Text

Open Access

Ultrasonography to measure gastric content in pregnant and nonpregnant female patients undergoing elective surgery

Semih Çelik,Engin İhsan Turan,Emirhan Kahraman,Oktay İnan,Ezgi Aydın İnan,Alican Ruşen,Ayça Sultan Şahin

Online publish date: 25 November 2025

DOI: 10.22514/sv.2025.184

Abstract ( 371 ) PDF (4.89 MB) ( 18 ) Full Text

Open Access

A new portable and ready-to-use device for out-of-hospital non-invasive treatment of acute respiratory failure: preclinical validation

Eleonora Salurso,Federica Ciceri Negri,Giacomo Monti,Tommaso Scquizzato,Glauco Bordoni,Luca Cabrini,Katia Donadello,Giuseppe Santarpino,Gianfranco Beniamino Fiore,Alberto Redaelli,Filippo Consolo,Giovanni Landoni

Online publish date: 25 November 2025

DOI: 10.22514/sv.2025.185

Abstract ( 525 ) PDF (6.68 MB) ( 52 ) Full Text

Open Access

Pain management in foot and ankle surgery: a multidisciplinary approach

Daniele Marcolli,Riccardo Caccialanza,Ivan Carrara,Diego Maria Michele Fornasari,Paolo Angelo Grossi

Online publish date: 20 November 2025

DOI: 10.22514/sv.2025.181

Abstract ( 544 ) PDF (942.51 kB) ( 34 ) Full Text

Editor-in-Chief

Prof. Giovanni Landoni, MD

Prof Giovanni Landoni, MD, is currently Full Professor and Residency Program Director of Anesthesia and Intensive Care Medicine at Vita-Salute San Raffaele University, Milan, Italy. He’s also Director of the Center for Intensive Care and Anesthesiology of San Raffaele Hospital in Milan, Italy. His strong clinical and research interests in intensive care and anesthesia resulted in more than 700 scientific publications in indexed journals, cited >20,000 times, h-index=75 on Scopus and 95 on Scholar, including randomized trials on NEJM, Lancet, and JAMA, and over 100 invitations in international congresses. He participated to 47 randomized controlled trials. Prof Landoni was Chief Investigator in successfully completed multicenter randomized clinical trials that randomized > 10,000 critically ill or perioperative patients over the last 10 years. He served as reviewer for over 50 journals (NEJM, JAMA, and The Lancet among others) and for foreign grant agencies, and he is member of the Editorial Board of several international journals.